Guest guest Posted November 1, 2006 Report Share Posted November 1, 2006 Medscape Neurology & Neurosurgery MedPulse® Neurology.Medscape.com SEARCH All Medscape MEDLINE Drug Reference Medscape Features Advertisement - Treating MS: How can you help reduce disease activity in all stages of relapsing multiple sclerosis? For information, click here. Advertisement - Treating Epilepsy - Which AED provides broad coverage of seizure types in both monotherapy and adjunctive therapy? Patient Education Find Resources For Your Patients Member Benefits Try a 30-day No Risk trial of ACP Medicine, the reference of the American College of Physicians. Evidence-based, peer-reviewed recommendations on current best practices. Learn More. Contact Us Editorial Comments Marni Kelman, MSc neuroeditor@... Technical Support mpmailings@... Mailing Address WebMD Medscape Attn: Email Newsletters 111 Eighth Avenue, 7th Floor New York, NY 10011 Ensure delivery - add Medscape_Neuro@... to your address book. Advertisement - Managing Insomnia: A Targeted Approach Why do experts consider targeting the SCN an attractive option for insomnia? Learn more. Sponsored by Takeda. Top Stories Vegetable Consumption Slows Rate of Cognitive Decline Specific Neurologic Complications Of Human Immunodeficiency Virus Type 1 (HIV-1) Infection In Children Schering Gets US OK for Betaseron in Early Stage MS Stroke Projected to Become Leading Cause of Death Parkinson's Disease Associated With Major Melanoma Risk How Prevalent Is The Persistence Of ADHD Into Adulthood? - ADHD continues from childhood into adulthood in as many as 50% to 80% of cases. Join Dr ph Biederman in exploring the treatment of ADHD patients from adolescence into adulthood, click here. Browse Neurology and Neurosurgery Content by Topic Feature Articles Conference Coverage American Neurological Association 131st Annual Meeting Read clinically focused news coverage of key developments from the meeting. Psychiatry Depression: Diagnosis and Treatment in Primary Care What 2 questions can you use to screen for depression? How can you distinguish unipolar from bipolar depression? What is the best way to treat depression using the results of the STAR*D study? Suicide and Bipolar Disorder Who is more likely to attempt suicide: a person with bipolar I or bipolar II? Who is more likely to succeed: a person with bipolar vs unipolar mood disorder? Why do the data seem puzzling at first? Medscape Psychiatry & Mental Health 11(2) 2006 Ethical Considerations in Medication-Free Research With Schizophrenia Patients: An Expert Interview With T. Carpenter, Jr., MD Is off-medication research for schizophrenia safe? Ethical? Are selection criteria skewed? Is psychosis neurotoxic? Can excessive dopamine cause psychosis? These and many relevant issues addressed. Medscape Psychiatry & Mental Health 11(2) 2006 Neurosurgery The History of Neurosurgical Procedures for Moyamoya Disease Almost 50 years of research on moyamoya disease has led to the development of a variety of management options. The authors discuss the history of surgical techniques for treatment. Neurosurg Focus 20(6) 2006 The Evolution of Endovascular Treatment for Intracranial Arteriovenous Malformations Read about catheter and embolic techniques and advances in fluoroscopic techniques and angiographic suites that have influenced the evolution of endovascular therapy for arteriovenous malformations. Neurosurg Focus 20(6) 2006 The History and Present Status of Deep Hypothermia and Circulatory Arrest in Cerebrovascular Surgery Learn about the history of hypothermia and circulatory arrest, its implementation in cerebrovascular surgery, and the changes in indications for and results of its use over time. Neurosurg Focus 20(6) 2006 Pediatrics Meningoencephalitis in a Child Complicated by Myocarditis, Quadriparesis and Respiratory Failure An 8-year-old Hispanic male resident of land developed fever to 38 degrees C, diffuse abdominal pain and dizziness. Pediatr Infect Dis J 25(9) 2006 Sleep Disturbance In Children With Migraine Do children with migraine have greater sleep disturbances than siblings? Does more severe migraine lead to greater levels of sleep disruption, greater behavioral problems, and more missed school? J Child Neurol 21(9) 2006 Specific Neurologic Complications Of Human Immunodeficiency Virus Type 1 (HIV-1) Infection In Children Read about cases of 7 children with unusual neurologic sequelae of HIV infection. The cases show that neurologic features of pediatric HIV infection do not fit into a simple classification system. J Child Neurol 21(9) 2006 Magnetic Resonance Imaging Study Of The Orbitofrontal Cortex In Autism The orbitofrontal cortex has many psychologic functions that can be impaired in autism. This study examined the size of the orbitofrontal cortex, and its medial and lateral subdivisions, using MRI. J Child Neurol 21(10) 2006 Other Neurology Topics Is Medical Student Choice of a Primary Care Residency Influenced by Debt? This article investigates whether medical student debt affects residency choice. Medscape General Medicine 8(4) 2006 Editorials Editorial: The Learning Curve This editorial introduces The Learning Curve's new editor, Gelber, as he welcomes medical students, residents, physicians, healthcare professionals, and interested readers to the eSection. Medscape General Medicine 8(4) 2006 Blueprint for Change: Will New Hospitals Be Safer Hospitals? Carolyn Clancy, MD, Director of the US AHRQ, discusses the safety of hospitals and how their redesign can make for better places of healing, working, and learning. Medscape General Medicine 8(4) 2006 The Patient Safety Movement Finally Is Saving Lives and Raising Hopes C. Schoenbaum, MD, MPH, Executive Vice President for Programs at The Commonwealth Fund in New York, tells a success story for hospital safety. Medscape General Medicine 8(4) 2006 Addiction: Do You Know The Latest Treatment Guidelines? Whether the devastating addiction is to alcohol, drugs, tobacco, gambling, food, or even technology, for the latest news, articles, practice guidelines, and more, click here. What Makes Bipolar Disorder So Hard To Diagnose and Treat? Bipolar disorder affects approximately 3% of people in the U.S., yet its complexities, variations, and frequent comorbid conditions can make diagnosis and treatment difficult. For helpful information, visit the Bipolar Disorder Resource Center. Industry Spotlight Information from Industry Antiepileptic Drug for Initial Epilepsy Monotherapy - Learn more about the only newer* antiepileptic drug to receive Level A recommendations for all types of refractory epilepsy. * Newer is defined by recent AAN/AES guidelines as the generation of AEDs approved by the FDA since 1990. News Pain GCH1 Gene Tied to Pain Sensitivity GTP cyclohydrolase (GCH1), the rate-limiting enzyme for tetrahydrobiopterin (BH4) synthesis, is a key modulator of peripheral neuropathic and inflammatory pain, researchers report in the November issue of Nature Medicine. Reuters Health Information 2006 Alzheimer's Disease Omega-3 Supplements Delay Cognitive Decline in Mild Alzheimer's Disease Omega-3 fatty acid supplements may slow cognitive decline in patients with very mild Alzheimer's disease, a study suggests. Medscape Medical News 2006 Mediterranean Diet Linked to Lower Alzheimer's Risk Consuming a Mediterranean diet can significantly reduce Alzheimer's Disease risk, but not necessarily through vascular mediation, a study suggests. Medscape Medical News 2006 Epilepsy Gamma Knife Surgery May Be Viable Alternative for Treatment of Intractable Epileptic Seizures Gamma knife radiosurgery may offer a safe, effective, noninvasive alternative for the treatment of mesial temporal lobe epilepsy, the most common cause of intractable epileptic seizures, a new study suggests. Medscape Medical News 2006 Multiple Sclerosis Schering Gets US OK for Betaseron in Early Stage MS German drugmaker Schering has received approval from U.S. regulators for the use of its Betaseron drug for early stage multiple sclerosis, it said on Monday. Reuters Health Information 2006 Methylthioadenosine Effective in Animal Models of Multiple Sclerosis Methylthioadenosine (MTA), an adenine nucleoside produced from S-adenosylmethionine, is effective in animal models of acute and chronic multiple sclerosis (MS), according to a report in the September issue of the ls of Neurology. Reuters Health Information 2006 Parkinson's Disease Impulse Control Disorders Common in Parkinson's Disease Two new studies examine the problematic disorders of impulse control, including repetitive behaviors, pathological gambling, and hypersexuality, seen in patients with PD, particularly those on dopamine agonists. Medscape Medical News 2006 Parkinson's Disease Associated With Major Melanoma Risk Patients with Parkinson's disease have a more than 2-fold increased risk of developing malignant melanoma compared with the general population, a new study has found. Medscape Medical News 2006 Parkinson's Genetic Data Now Publicly Available For the first time, genetic data that have the potential to facilitate possible breakthroughs in Parkinson's disease are publicly available. Two large studies are being hailed as a major contribution to current the body of scientific knowledge about the disease, which previous research has shown has a strong genetic component. Medscape Medical News 2006 Stroke Drug-Eluting Stents Appear Safe in the Cranial Circulation Drug-eluting stents may be safely used to treat stenoses in the intracranial and extracranial circulation and may be less likely to develop restenoses than bare metal stents, according to a report in the October issue of Stroke. Reuters Health Information 2006 Statins Reduce Risk of Stroke, MI in Carotid Arterial Disease Statins are very effective in preventing secondary events or death in patients with severe carotid arterial disease, new research shows. All patients with this disease who are deemed high risk should be treated with statins, say the investigators. Heartwire 2006 Microcerebral Ischemia Marker Signals Hemorrhage Risk With Stroke Thrombolysis Thrombolysis during the first 3 hours after stroke symptom onset may be inadvisable if MRI reveals leukoaraiosis, which suggests the patient may have an increased risk of intracerebral hemorrhage, report researchers with the MR Stroke Study, an international research effort to standardize the use of MRI in acute stroke. Reuters Health Information 2006 Stroke Symptoms Common in the General Population Almost 18% of a sample of the US population with no prior diagnosis of stroke or transient ischemic attack (TIA) had at least 1 stroke symptom, and individuals with more stroke risk factors were more likely to have stroke symptoms. These findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study are reported in the October 9 issue of the Archives of Internal Medicine. Medscape Medical News 2006 Early Coronary Revascularization After MI Cuts Stroke Risk The faster that thrombolytic therapy or angioplasty can be applied after an MI, the lower the chances that the patient will also experience a stroke, new research suggests. Reuters Health Information 2006 Stroke Projected to Become Leading Cause of Death The growing problem of stroke has been highlighted by data suggesting that this condition is now the second leading cause of death worldwide (after heart disease), and is projected to be the leading cause of death by 2030. Heartwire 2006 Pediatrics Perinatal Antiretroviral Drug Exposure Does Not Impair Neurodevelopment Neurodevelopment is unaffected in children not infected with HIV but who are exposed perinatally to antiretroviral drugs, according to a report in the October issue of Pediatrics. Reuters Health Information 2006 Intellectual Disabilities Often Accompanied by Psychopathology Four out of ten children with mental retardation also have severe emotional and behavioral problems, which often persist into adulthood, according to results of a longitudinal study conducted in Australia. However, according to a report in the Journal of the American Medical Association for October 25, few of those with psychological problems received any mental health therapy in this study. Reuters Health Information 2006 Abdominal Obesity in Children Linked to Central but Not Obstructive Sleep Apnea In overweight children with sleep-disordered breathing, higher levels of abdominal obesity and fat mass were associated with central but not with obstructive sleep apnea (OSA), according to the results of a study reported in the October 13 Online First issue of Archives of Disease in Childhood. Medscape Medical News 2006 Headache Adolescent Migraine Tends to Subside With Age A large proportion of children and teens who suffer from migraines will eventually outgrow them, a new study suggests. Medscape Medical News 2006 Overuse of Ergotamine but Not Triptans Increases Risk for Ischemia In a nested case-control study, overuse of ergotamine, but not overuse of triptans, increased the risk for ischemia in patients with migraines. Medscape Medical News 2006 Other Neurology Topics Magnetic Resonance Neurography Helps Spot Extraspinal Sciatica Magnetic resonance (MR) neurography helps find muscular entrapment of the sciatic nerve in patients with normal results on MR imaging for lumbosacral radiculopathy, researchers report in the October issue of the Archives of Neurology. Reuters Health Information 2006 No Adverse Effects of Generic Warfarin, but Major Cost Savings Substitution of generic warfarin for Coumadin in Ontario had no appreciable effect on rates of INR testing or hospitalization for major hemorrhage or cerebral thromboembolism, researchers say. Cost, however, was much lower. Heartwire 2006 Vegetable Consumption Slows Rate of Cognitive Decline A study has shown an association between slowed cognitive decline and vegetable consumption. Individuals who consumed at least 2.8 servings of vegetables per day slowed their rate of cognitive decline by roughly 40% compared with those who consumed less than 1 serving per day �� a decrease that is equivalent to about 5 years of younger age. Medscape Medical News 2006 Comorbid Anxiety Disorders Worsen Effects of Physical Diseases Patients with physical maladies are at increased risk of having an anxiety disorder as well, a multinational research group reports in the Archives of Internal Medicine for October 23. Furthermore, the severity of the physical illness and resulting loss of function are exacerbated among patients with comorbid anxiety. Reuters Health Information 2006 Connectivity Patterns in Brain Altered in Autism The number of neural connections in the left temporal lobe is abnormally high in the brains of patients with autism, while connectivity between the frontal lobe and the rest of the brain is decreased. Reuters Health Information 2006 Regulatory Rulings FDA Safety Changes: Zanaflex, Adderall, Adderall XR The FDA has approved revisions to the safety labeling tizanidine HCl and mixed salts of a single-entity amphetamine product. Medscape Medical News 2006 FDA Approvals: Risperdal/Risperdal M-TAB, Travatan Z, Rituxan The FDA has approved a new indication for risperidone oral solution/tablets and orally disintegrating tablets (Risperdal and Risperdal M-TAB), travoprost 0.004% ophthalmic solution (Travatan Z), and 2 new indications for rituximab intravenous infusion (Rituxan). Medscape Medical News 2006 International Approvals: Sebivo and Tysabri Switzerland has approved telbivudine tablets (Sebivo), and Canada has approved natalizumab injection (Tysabri). Medscape Medical News 2006 Instant Poll Free Lunch Recent reports have described the practice of pharmaceutical companies providing lunch to medical practices while reps pitch their drugs to the physicians. The companies say the lunches are modest and fall within industry guidelines. Opponents say that modest or not, they still influence prescribing practices. Do you favor or oppose the free lunch? To vote or view results of the poll, click on the title above. User Support Unsubscribe from this newsletter Subscribe to this newsletter Not yet a Medscape member? Forgot your login info? Add MedPulse to your email 'Safe List' or Personal Address Book Cannot read this newsletter? Prefer the TEXT version? http://mp.medscape.com/cgi-bin1/DM/y/hBBjR0MIRYV0D2K0FqjA0Ej Difficulty linking to a news story? Difficulty Viewing Images? Need additional support? Note for AOL subscribers: To unsubscribe from this newsletter, please click on the unsubscribe link above rather than clicking on the " Report Spam " button in your AOL inbox. If you have difficulty unsubscribing, please contact Medscape directly at mpmailings@.... 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