Guest guest Posted August 21, 2001 Report Share Posted August 21, 2001 In a message dated 08/22/2001 1:07:08 AM Central Daylight Time, Rpolychondritis writes: << He said that the redness, swelling, and discomfort (bugs crawling etc.) are vascular in nature. >> Kim, Thanks for the information. I was diagnosed in 1997, so have had the redness, swelling, etc., but NEVER the buggy feeling. I don't like it! Thanks again, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2001 Report Share Posted August 25, 2001 I finally read the emedicine article that someone here posted http://www.emedicine.com/derm/topic375.htm (I think it was Connie): Under Methotrexate/Interactions, here's what it says: Oral aminoglycosides may decrease absorption and blood levels of concurrent oral MTX; charcoal lowers MTX levels; coadministration with etretinate may increase hepatotoxicity of MTX; folic acid or its derivatives contained in some vitamins may decrease response to MTX; coadministration with NSAIDs may be fatal; indomethacin and phenylbutazone can increase MTX plasma levels; may decrease phenytoin serum levels; probenecid, salicylates, procarbazine, and sulfonamides, including TMP-SMZ, may increase effects and toxicity of MTX; may increase plasma levels of thiopurines. I think it's interesting that it also says Folic Acid decreases MTX's response. I take both vioxx and folic acid... forgot to mention this to my rheum last thurs. ===== When choosing the lesser of two evils, I always like the one I haven't tried. -- Mae West __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2001 Report Share Posted August 25, 2001 In a message dated 8/25/01 5:46:01 PM Pacific Daylight Time, hiacynth1@... writes: << I think it's interesting that it also says Folic Acid decreases MTX's response. I take both vioxx and folic acid... forgot to mention this to my rheum last thurs. >> , when I was on metho, they made me stop taking vioxx a month before I could start the metho....Said there were fatalities related to anti inflamatories and mehto... I was going to an overly causious dr at the time.... There have been many arguments over the folic acid and metho....All my drs agreed that I should take it.... It did help with the side effects, but maybe that is why the metho didn't work for me... don't know... hugs Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2001 Report Share Posted August 26, 2001 HI ALL THE OTHER INTERESTING THING THAT THIS SAYS IS coadministration with NSAIDs may be fatal. NSAIDS INCLUDES, NAPROXSEN, VIOXX, CLELEBREX, ASPRIN, AND ANY OTHER ANIT INFLAMMATORY.ASK YOUR DRS ABOUT THIS. DAWN " B." wrote: I finally read the emedicine article that someonehere postedhttp://www.emedicine.com/derm/topic375.htm (Ithink it was Connie): Under Methotrexate/Interactions, here's what itsays: Oral aminoglycosides may decrease absorption andblood levels of concurrent oral MTX; charcoallowers MTX levels; coadministration withetretinate may increase hepatotoxicity of MTX;folic acid or its derivatives contained in somevitamins may decrease response to MTX;coadministration with NSAIDs may be fatal;indomethacin and phenylbutazone can increase MTXplasma levels; may decrease phenytoin serumlevels; probenecid, salicylates, procarbazine,and sulfonamides, including TMP-SMZ, may increaseeffects and toxicity of MTX; may increase plasmalevels of thiopurines.I think it's interesting that it also says FolicAcid decreases MTX's response. I take both vioxxand folic acid... forgot to mention this to myrheum last thurs.=====When choosing the lesser of two evils,I always like the one I haven't tried. -- Mae West__________________________________________________ Quote Link to comment Share on other sites More sharing options...
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