Constipation & insomnia

[Guest guest]

well i never thought of that how about you chris? good idea!!!

>From: C <covo@...>

>Reply-low dose naltrexone

>low dose naltrexone

>Subject: Re: [low dose naltrexone] Constipation & insomnia

>Date: Fri, 27 Oct 2006 08:55:22 +1000

>

>

>

>What about changing the filler to hopefully eliminate the constipation

>issue?

>

>

>

>chriskjezp wrote:

>

> >I've tried starting LDN twice now. The first time it was 4.5 mg

>capsules. I had to stop after

> >two nights because of severe insomnia (something I already struggle with,

>so I wasn't

> >surprised that LDN affected me this way based upon what I had read). It

>also seemed to

> >make me constipated, which also posed a problem since constipation is

>also a symptom I

> >deal with regularly (I have Crohn's Disease, but it is a very atypical

>case).

> >

> >Then I found out here that it might be better to start at 1.5 mg and

>slowly build up.

> >However, after just two night of 1.5 mg from Skip's, I again had to stop

>for the same reasons.

> >

> >I'm wondering if anyone else out there has had a similar reaction, and if

>there's any way to

> >overcome it. I am intrigued by the theory behind LDN and was very

>impressed by Dr. 's

> >study results. I do not wish to take steroids, and Pentasa hasn't worked

>for me at all. LDN is

> >my best hope at this point.

> >

> >Any help you could offer would be greatly appreciated.

> >

> >Best,

> >Chris

> >

> >

>

>

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[Guest guest]

I take LDN for MS, so the constipation issue is probably

different, but I did find after a year that I was extremely

constipated, a new experience for me. I began taking digestive enzymes

(animal-based) and I've been fine ever since.

[Guest guest]

Malic acid, (magnesium) works wonders and helps with muscle soreness.

[low dose naltrexone] Re: Constipation & insomnia

I take LDN for MS, so the constipation issue is probably

different, but I did find after a year that I was extremely

constipated, a new experience for me. I began taking digestive enzymes

(animal-based) and I've been fine ever since.

[Guest guest]

>

>

>

> What about changing the filler to hopefully eliminate the constipation

> issue?

>

>

,

What filler would be less likely to be constipating. The first prescription I

had was from

Irmat, and the second from Skip's.

Thanks,

Chris

[Guest guest]

chrisif you were having trouble sleeping it will go away. if you are constipated you should call skip. cyndiOn Oct 27, 2006, at 12:57 AM, Kathy Lintzenich wrote: Take the 1.5 and only do half the powder until you get used to it. In addition, take whatever you use (magnesium,sleeping pill, etc) to induce sleep. Magnesium also helps constipation. Best, Kathy [low dose naltrexone] Constipation & insomnia I've tried starting LDN twice now. The first time it was 4.5 mg capsules. I had to stop after two nights because of severe insomnia (something I already struggle with, so I wasn't surprised that LDN affected me this way based upon what I had read). It also seemed to make me constipated, which also posed a problem since constipation is also a symptom I deal with regularly (I have Crohn's Disease, but it is a very atypical case).Then I found out here that it might be better to start at 1.5 mg and slowly build up. However, after just two night of 1.5 mg from Skip's, I again had to stop for the same reasons. I'm wondering if anyone else out there has had a similar reaction, and if there's any way to overcome it. I am intrigued by the theory behind LDN and was very impressed by Dr. 's study results. I do not wish to take steroids, and Pentasa hasn't worked for me at all. LDN is my best hope at this point.Any help you could offer would be greatly appreciated.Best,Chris

[Guest guest]

enzymes are awesome but because chris has chrohns she really needs to

call skip.

cyndi

On Oct 26, 2006, at 8:31 PM, creiaa wrote:

> I take LDN for MS, so the constipation issue is probably

> different, but I did find after a year that I was extremely

> constipated, a new experience for me. I began taking digestive

> enzymes

> (animal-based) and I've been fine ever since.

>

>

>

>

[Guest guest]

>

> enzymes are awesome but because chris has chrohns she really needs to

> call skip.

> cyndi

Thanks, I will call Skip. I've taken every brand of enzymes imaginable and also

many

remedies, both allopathic and alternative, for constipation. Since constipation

and insomnia

are probably the two most persistent and disturbing symptoms I have, it's a real

shame that

those are the two side effects of LDN. Makes it very difficult to take it.

Chris

P.S. Not that it matters too much on an Internet board, but I'm a " he " not a

" she " .

[Guest guest]

>

> Take the 1.5 and only do half the powder until you get used to it. In

addition, take

whatever you use (magnesium,sleeping pill, etc) to induce sleep. Magnesium also

helps

constipation. Best, Kathy

What do you mean by " half the powder " ? Do I have to order a special formulation

from Skip?

[Guest guest]

>

> Malic acid, (magnesium) works wonders and helps with muscle soreness.

>

Conni,

I did a bit of research and malic acid looks promising. Is there a brand or

specific formula

you recommend? There are a lot of choices out there.

Thanks,

Chris

[Guest guest]

>

> I take LDN for MS, so the constipation issue is probably

> different, but I did find after a year that I was extremely

> constipated, a new experience for me. I began taking digestive enzymes

> (animal-based) and I've been fine ever since.

>

>

>

I was under the impression that LDN causes constipation because it stimulates

opioid

production. Many drugs that affect opioids, such as benzodiazapenes like

Restoril and

Klonopin, are known to cause constipation.

Is this not true for LDN as well?

[Guest guest]

Give us an idea of what

you eat during the day.

breakfast

lunch

supper

snacks

[Guest guest]

I find when I eat a packet of oatmeal each day, everything keeps on moving. Before that, 800 MG Magnesium was helping greatly.

RE: [low dose naltrexone] Re: Constipation & insomnia

Malic acid, (magnesium) works wonders and helps with muscle soreness.-----Original Message-----From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of creiaaSent: Thursday, October 26, 2006 8:31 PMlow dose naltrexone Subject: [low dose naltrexone] Re: Constipation & insomnia I take LDN for MS, so the constipation issue is probably different, but I did find after a year that I was extremely constipated, a new experience for me. I began taking digestive enzymes (animal-based) and I've been fine ever since.

[Guest guest]

--- In

Dr. McC,

I witnessed two or 3

people on the LDN

board experience severe

negative mood swings upon

starting LDN, one with

ALS and another with

multiple sclerosis.

Both had to stop taking

LDN.

I'm wondering if food

they're eating combined

with the LDN might be

causing this negative

reaction.

Dr. J.M., your thoughts.

I would love to find a

way for these

people to be able to

return to LDN.

==========

[Guest guest]

Take the 1.5 and only do half the powder until you get used to it. In addition, take whatever you use (magnesium,sleeping pill, etc) to induce sleep. Magnesium also helps constipation. Best, Kathy

[low dose naltrexone] Constipation & insomnia

I've tried starting LDN twice now. The first time it was 4.5 mg capsules. I had to stop after two nights because of severe insomnia (something I already struggle with, so I wasn't surprised that LDN affected me this way based upon what I had read). It also seemed to make me constipated, which also posed a problem since constipation is also a symptom I deal with regularly (I have Crohn's Disease, but it is a very atypical case).Then I found out here that it might be better to start at 1.5 mg and slowly build up. However, after just two night of 1.5 mg from Skip's, I again had to stop for the same reasons. I'm wondering if anyone else out there has had a similar reaction, and if there's any way to overcome it. I am intrigued by the theory behind LDN and was very impressed by Dr. 's study results. I do not wish to take steroids, and Pentasa hasn't worked for me at all. LDN is my best hope at this point.Any help you could offer would be greatly appreciated.Best,Chris

[Guest guest]

Chris

Dr McCandless developed a transdermal LDN cream for autistic kids.... this bypasses the gut and maybe a solution for you.

I forget offhand the pharmacy that compounds it.

mjh"The Basil Book"http://foxhillfarm.us/FireBasil/

I'm wondering if anyone else out there has had a similar reaction, and if there's any way to overcome it. I am intrigued by the theory behind LDN and was very impressed by Dr. 's study results. I do not wish to take steroids, and Pentasa hasn't worked for me at all. LDN is my best hope at this point.Any help you could offer would be greatly appreciated.Best,Chris

[Guest guest]

I'm not sure, sorry. Just know that occasionally some people have

different stomach (and/or nausea) issues and a change of filler

sometimes eliminates the problem. It may not either in which case you'd

be lead to the conclusion that it was the actual naltrexone itself

causing the problem.

chriskjezp wrote:

>

>

>

>>

>>

>>What about changing the filler to hopefully eliminate the constipation

>>issue?

>>

>>

>>

>>

>

>,

>

>What filler would be less likely to be constipating. The first prescription I

had was from

>Irmat, and the second from Skip's.

>

>Thanks,

>Chris

>

>

[Guest guest]

Hello everyone,

I hate to sound like an old salt here, but I'm pretty sure the issue

isn't diet. Over the past seven years I've tried every special diet

you can imagine - SCD, gluten-free, Maker's Diet, macrobiotics, IBS-

diet (low-fiber), high-fiber, etc. etc. After many classes,

consultations with experts and my own experimentation, I feel I have

an excellent understanding of nutrition and food and the extent to

which diet is a factor in my condition. I can tell you that it

certainly is a factor, but not the only one, and a gluten-free diet

or SCD only made constipation worse. Currently I eat a fairly

moderate diet (not too restrictive) including fresh vegetables,

fruits, whole grains, fish, poultry, and omega-3 oils, and this seems

to work better for me than anything else I've tried.

Before starting LDN, I completed something called a " probiotic

infusion " (fecal bacteriotherapy) which is a new treatment that takes

flora from a healthy human donor and implants it into the sick

person's (me) colon. That had a dramatic effect and essentially

relieved my constipation.

The reason I know constipation is directly related to LDN is that for

those few weeks prior to starting it (and after the probiotic

infusion described above), I was quite regular. Then the very next

day after taking LDN, that changed. When I stopped LDN, I became

regular again. Seems fairly straightforward.

I'm open to the possibility that the filler has something to do with

it, and I will call Skip today to discuss that. I also keep thinking

about the fact that other drugs that affect opioid production and

regulation frequently cause constipation, so I wonder why this isn't

often discussed with LDN.

Thanks for all of your help and concern,

Chris

[Guest guest]

Also, forgot to mention - I have had several tests for celiac disease

which have been negative.

[Guest guest]

Interesting observation, I never thought that LDN could cause it, myself, but what you say makes sense. The filler makes the most sense as the possible culprit if not the naltrexone itself. Observations like these are important, keep us posted about the change in filler, if it helps you. >> Hello everyone,> > I hate to sound like an old salt here, but I'm pretty sure the issue > isn't diet. Over the past seven years I've tried every special diet > you can imagine - SCD, gluten-free, Maker's Diet, macrobiotics, IBS- > diet (low-fiber), high-fiber, etc. etc. After many classes, > consultations with experts and my own experimentation, I feel I have > an excellent understanding of nutrition and food and the extent to > which diet is a factor in my condition. I can tell you that it > certainly is a factor, but not the only one, and a gluten-free diet > or SCD only made constipation worse. Currently I eat a fairly > moderate diet (not too restrictive) including fresh vegetables, > fruits, whole grains, fish, poultry, and omega-3 oils, and this seems > to work better for me than anything else I've tried.> > Before starting LDN, I completed something called a "probiotic > infusion" (fecal bacteriotherapy) which is a new treatment that takes > flora from a healthy human donor and implants it into the sick > person's (me) colon. That had a dramatic effect and essentially > relieved my constipation.> > The reason I know constipation is directly related to LDN is that for > those few weeks prior to starting it (and after the probiotic > infusion described above), I was quite regular. Then the very next > day after taking LDN, that changed. When I stopped LDN, I became > regular again. Seems fairly straightforward.> > I'm open to the possibility that the filler has something to do with > it, and I will call Skip today to discuss that. I also keep thinking > about the fact that other drugs that affect opioid production and > regulation frequently cause constipation, so I wonder why this isn't > often discussed with LDN.> > Thanks for all of your help and concern,> Chris>

[Guest guest]

>

>

> Hello and a big Thanks

to Dave and all

others who contributed

> to this post.

>

> I've been dealing with

my own major gut issues

for quite some time. A

> year ago was treated

with heavy duty anti-

biotics for an

> H.Pylori/ulcer problem

which resolved but re-

newed an old

> candida/dysbiosis

problem. Just when I

thought I was getting

this new

> problem under control,

I began LDN in Feb. of

this year and noticed

> more difficulties with

constipation/candida.

It's been a long roller

> coaster ride trying so

many different things -

the candida diet,

> pro-biotics, grapefruit

seed extract, colloidal

silver, Threelac, the

> latest being oil of

wild oregano and

combinations of all the

above.

> Have only had limited

success after spending

many $$. The candida was

> so bad + making me feel

so aweful, that I almost

gave up on LDN

> thinking it wasn't

working for the MS and

like my doctors, blaming

my

> symptoms on MS rather

than candida. Glad I

didn't !!

>

> Have been seeing a GI

doctor who has not been

very helpful - they

> don't really have a

clue when it comes to gut

flora imbalance. She's

> done every test

possible on me to

diagnose my abdominal

>

pain/constipation/weakness

etc. and has come up

with my gallbladder

> contracting less than

normal and suggesting it

being removed. I

> refused and am seeing a

new GI doctor this coming

Tuesday.

>

> Will be seriously

checking into this

transdermal option.

Thanks again

> for connecting the dots.

>

> Andre

=========

Andre

Do you have any

mercury/amalgam dental

fillings?

[Guest guest]

Excellent observation Andre, " Not all pro-biotics are good quality " .

I take Inner Health plus, dairy free, myself (only in Oz as far as I know) so I

would add it is

imperative to ensure recommended temperature is maintained (2-8 degrees C) when

transporting from

shop to home to safeguard quality.

One day, I forgot I'd purchased it and remembered hours later. Had to throw it

in the bin and buy

another one - that hurt!

I've been taking between one and four capsules per day as an experiment - each

contains 2.5 billion

each of Lactobacillus Acidophilus and Bifidobacterium Lactis.

After around 3 months of trialling I believe one capsule a day is ineffective

for addressing a

health issue.

Regards,

Cris

4b. Re: Constipation & insomnia

Posted by: " ajdd63 " AJDION@... ajdd63

Date: Sun Oct 29, 2006 1:51 pm (PST)

Hello Gayle,

During the long periods between MD appointments I have plenty of time

to read/research and found certain symptoms just don't add up as

having anything to do with MS. Abdominal pain, slow digestion,

intermittent constipation, gall bladder problems etc. are all to do

with GI. When the colon is not working right from what I've read this

also puts stress on the liver, gall bladder, bladder, kidneys and

pancreas due to an impacted colon putting pressure on these other

organs. Another thing it can cause is this 'leaky gut syndrome' which

causes you to be allergic to foods that used to be no problem - for

me, soy and carrots, when undigested food proteins pass through the

intestinal wall. After it was suggested that I have my gall bladder

removed, I looked at alternatives and decided to try this 5 day

liver/gall bladder detox juice fast which took care of my liver and

gall bladder. I avoided surgery and am starting to digest much better.

My next plan is to do a similar 5 day cleansing for my kidneys, since

I've been having problenms in this department. Not all pro-biotics are

good quality. The best I've found that works for me is Primal Defense

made by - Garden of Life ? The trick too is to use enough of it. I can

just sense these bacteria doing their thing in my gut a couple hours

after taking them.

One final comment on the constipation. I may be wrong about LDN

causing my constipation. Now think it is more to do with trying to

detox too rapidly. Have been new to this oil of wild oregano which is

triple strength along with taking grapefruit seed extract. Have read

that when detoxing, the body is getting rid of all this candida and

other waste which if done too fast will block things up. Have backed

off a little on my dose and see a little improvement. Patience can be

a difficult virtue to cultivate. Hope this helps.

Andre