Guest guest Posted August 1, 2006 Report Share Posted August 1, 2006 Folks, I don't understand something and it's been bugging me ever since I started taking LDN. My problem is about taking it at some arbitrary, specific time of day rather than a biological based time as I first thought e.g., " Bed Time " . Saying to take it between 7 and 11 P.M. makes almost no sense. Are the instructions for EDT or PDT or something else. If EDT, what does a person do who lives in the Antarctic or who works a graveyard shift or something else? I think it makes more sense to take it at “bedtime” i.e., when you go to bed. Your Circadian rhythm makes more sense to determine times to take medicines. The description about why doctors think LDN works is based on your sleep cycle not an arbitrary time of the day. It means LDN will work for anyone without regard to their work schedule, where they live or under what physical conditions they live (e.g., in an underground bunker). Does anyone have a problem with taking LDN at Bedtime vs. at a specific time of day and do you have any rationale for that? Larry Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 28, 2007 Report Share Posted June 28, 2007 I respectfully disagree with those that believe releasing of endorphins has to do with time of day or geographical location compared to a person's sleep cycle. Our biological clock is an extremely powerful mechanism. I am still researcing the universality of the time of day for the release of endorphins. Do Doctors in the UK instruct MS patients to take LDN at a different times than those in the US? If you work 'graveyard' shift should you take LDN right before you start work (I doubt it). What if you live underground in the Antarctic? The only reliable constant for how our body behaves is our body. Our bodies are flexible. If you sleep from 6AM to 2PM daily you will get tired at 6AM and be wide awake at 11 at night. And I suspect if your endorphin levels are monitored, the cycle would be changed (I am trying to research this). It just makes more sense to me that your location on the globe has little to do with when you should take LDN Larry > > > > Folks, > > I don't understand something and it's been bugging me ever since I started > > taking LDN. My problem is about taking it at some arbitrary, specific time > > of day rather than a biological based time as I first thought e.g., " Bed > > Time " . > > > > Saying to take it between 7 and 11 P.M. makes almost no sense. Are the > > instructions for EDT or PDT or something else. If EDT, what does a person > > do who lives in the Antarctic or who works a graveyard shift or something > > else? I think it makes more sense to take it at " bedtime " i.e., when you go > > to bed. Your Circadian rhythm makes more sense to determine times to take > > medicines. The description about why doctors think LDN works is based on > > your sleep cycle not an arbitrary time of the day. > > > > It means LDN will work for anyone without regard to their work schedule, > > where they live or under what physical conditions they live (e.g., in an > > underground bunker). Does anyone have a problem with taking LDN at Bedtime > > vs. at a specific time of day and do you have any rationale for that? > > > > Larry > > > ========= > > Go to the LDN website and especially read the Further Q and A page there, it will answer some of your questions about why LDN is taken between the hours of 9pm and 3am no matter what time zone one is in or shift a person works. > > LDN website > http://www.ldninfo.org > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 28, 2007 Report Share Posted June 28, 2007 BRENDA - if i administer the transdermal at midnight; whether it's daylight saving time, eastern daylight time - should it matter, one way or the other?? i don't think so; what are your thoughts about that?? i figure i'm within the time slot, which ever TIME we're having, in Penna. marshiris@... See what's free at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 28, 2007 Report Share Posted June 28, 2007 > > I respectfully disagree with those that believe releasing of > endorphins has to do with time of day or geographical location > compared to a person's sleep cycle. Our biological clock is an > extremely powerful mechanism. I am still researcing the > universality of the time of day for the release of endorphins. > > Do Doctors in the UK instruct MS patients to take LDN at a different > times than those in the US? If you work 'graveyard' shift should > you take LDN right before you start work (I doubt it). What if you > live underground in the Antarctic? The only reliable constant for > how our body behaves is our body. > > Our bodies are flexible. If you sleep from 6AM to 2PM daily you > will get tired at 6AM and be wide awake at 11 at night. And I > suspect if your endorphin levels are monitored, the cycle would be > changed (I am trying to research this). > > It just makes more sense to me that your location on the globe has > little to do with when you should take LDN > > Larry ========== Here's something to think about. My grandma takes LDN for Alzheimer's, here in the states we have DST(Daylight Saving Time). My grandma was doing great on LDN and then we had a time change which really made her be taking her LDN at 8pm instead of 9pm, I had forgotten to tell my uncle to change her LDN to 10pm and within 5 days of the time change my grandma's mental state started slipping terribly, all the gains she'd made were fading fast and it hit me that she was actually taking her LDN at 8pm since we'd had a time change. I told family members to change LDN dose to 10pm and within 2 nights my grandma was back to where we'd had her before. The only other time she has slipped back into a devastating mental state was when she had major surgery and had to be off LDN for 2 weeks, that was nightmarish. Back on LDN 2 nights and she started to recover to where she was before the surgery. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 28, 2007 Report Share Posted June 28, 2007 > > BRENDA - if i administer the transdermal at midnight; whether it's daylight > saving time, eastern daylight time - should it matter, one way or the > other?? i don't think so; what are your thoughts about that?? i figure i'm within > the time slot, which ever TIME we're having, in Penna. ========== That's fine. Quote Link to comment Share on other sites More sharing options...
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