Guest guest Posted August 14, 2006 Report Share Posted August 14, 2006 what is trans-dermal LDN? this is the first I have heard of it Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 I think it is an oil or cream that is applied to your skin. It is used for children with Autism because it is easier to give to them and because it does not get digested which is good because Autistic children generally have problems with their gut. This is what I remember, I hope someone will correct me if I am mistaken. Thanks Aletha Re: [low dose naltrexone] LDN compounding what is trans-dermal LDN? this is the first I have heard of it Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 It seems to be how people treating kids with autism spectrum disorders prefer to use it...it's mixed with Emu Oil (someone correct me if I've got this wrong). And I THINK I saw that maybe it's better for people with spasticity problems from LDN... Gayle From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of Chrissismissng@...Sent: Tuesday, 15 August 2006 10:46 AMlow dose naltrexone Subject: Re: [low dose naltrexone] LDN compounding what is trans-dermal LDN? this is the first I have heard of it __________ NOD32 1.1706 (20060814) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 Also try the soap trick with leg cramps and let us know if it works. Aletha [low dose naltrexone] LDN compounding Hi folks - back on this again…I just spoke to my current compounder. He's using pure Naltrexone powder, not the tablets. My misunderstanding, and he wasn't there to check with last week. The filler has been Avicel, so everything seems to have been done the right way. Since I'm very low in my supply I'm getting him to make up this next lot, but trying lactose as the filler instead of Avicel. I'm still planning to switch to the Green Pharmacy (Australia). After this (MS) relapse settles, do I try going up to 4.5mg? I had pretty bad leg spasms on first starting LDN, but that settled after a few weeks. Do I give liquid LDN a try? Or trans-dermal? Gayle Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 > > It seems to be how people treating kids with autism spectrum disorders > prefer to use it...it's mixed with Emu Oil (someone correct me if I've got > this wrong). And I THINK I saw that maybe it's better for people with > spasticity problems from LDN... > Gayle > -- TD(Transdermal LDN), a rub on the skin LDN. Dr. Jaquelyn McCandless has found a TD LDN made with Emu oil that absorbs quickly into the blood stream for her autistic patients. This TD LDN bypasses the liver and stiffness usually stems from LDN having to pass through the liver. The TD LDN is applied anywhere on the body like stomach, legs, arms. And it's applied between the hours of 9pm and 3am. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 I did try the soap trick - and to my utter shock it seemed to work... Gayle From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of Aletha WittmannSent: Tuesday, 15 August 2006 12:16 PMlow dose naltrexone Subject: Re: [low dose naltrexone] LDN compounding Also try the soap trick with leg cramps and let us know if it works. Aletha [low dose naltrexone] LDN compounding Hi folks - back on this again…I just spoke to my current compounder. He's using pure Naltrexone powder, not the tablets. My misunderstanding, and he wasn't there to check with last week.. The filler has been Avicel, so everything seems to have been done the right way. Since I'm very low in my supply I'm getting him to make up this next lot, but trying lactose as the filler instead of Avicel. I'm still planning to switch to the Green Pharmacy (Australia). After this (MS) relapse settles, do I try going up to 4.5mg? I had pretty bad leg spasms on first starting LDN, but that settled after a few weeks. Do I give liquid LDN a try? Or trans-dermal? Gayle __________ NOD32 1.1706 (20060814) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 it has to be in emu oil according to dr m and like i said you can ask your pharmacist to call the pharmacist at coastal compounding and he will share the forumla cyndi i'm still out in colorado-things are going very slow. [low dose naltrexone] Re: LDN compounding > > >> >> It seems to be how people treating kids with autism spectrum >disorders >> prefer to use it...it's mixed with Emu Oil (someone correct me if >I've got >> this wrong). And I THINK I saw that maybe it's better for people >with >> spasticity problems from LDN... >> Gayle >> > >-- > >TD(Transdermal LDN), a rub on the skin LDN. Dr. Jaquelyn McCandless >has found a TD LDN made with Emu oil that absorbs quickly into the >blood stream for her autistic patients. This TD LDN bypasses the >liver and stiffness usually stems from LDN having to pass through the >liver. > >The TD LDN is applied anywhere on the body like stomach, legs, arms. >And it's applied between the hours of 9pm and 3am. > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 Way cool!!! [low dose naltrexone] LDN compounding Hi folks - back on this again…I just spoke to my current compounder. He's using pure Naltrexone powder, not the tablets. My misunderstanding, and he wasn't there to check with last week.. The filler has been Avicel, so everything seems to have been done the right way. Since I'm very low in my supply I'm getting him to make up this next lot, but trying lactose as the filler instead of Avicel. I'm still planning to switch to the Green Pharmacy (Australia). After this (MS) relapse settles, do I try going up to 4.5mg? I had pretty bad leg spasms on first starting LDN, but that settled after a few weeks. Do I give liquid LDN a try? Or trans-dermal? Gayle __________ NOD32 1.1706 (20060814) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 Transdermal preparations are used to put the drug thru the skin into the systemic circulation. It is just another route of administration. There is no big mystery here. I would only recommend it when you are unable to take a capsule. The pharmacokinetecs and dynamics are different from the oral. Your pharmacist has to be careful about the type of Emu Oil that they use. There is cheap stuff out there that doesn't work. They should use the standard PLO formula but replace the lecithin solution with Emu. It is compounded just like any other PLO. The guys at Coastal were very helpful so I would have my pharmacist contact them BEFORE making it. The interesting thing about td LDN is that for the longest time I was afraid of using it. The structure of the molecule is outside the range for TD use. It wasn't until another compounder sent me some info on patients using it that I began to investigate it. The kids were having sleep disturbances around 3-4A. Bingo. This is a gold standard for it being absorbed and appropriately being utilized by the body. So, even old farts like me can learn new tricks. Skip Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 Skip What is your opinion of DMSO as a carrier for LDN TD? mjh"The Basil Book"http://foxhillfarm.us/FireBasil/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2006 Report Share Posted August 15, 2006 I do not believe that DMSO is an appropriate vehicle for any drug used in humans, and I question there use in animals. Note that I said USE, not that it is ineffective. DMSO is probably THE most effective TD vehicle. The problem is that it will carry everything on the skin thru to systemic circulation. With all of the folks doing their own thing, and the unknown constituents in some of these products I would never recommend it. Its like using an atomic bomb to kill ants. The PLO with emu oil has been shown to be very effective with no reported side-effects. Skip Quote Link to comment Share on other sites More sharing options...
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