Guest guest Posted August 17, 2002 Report Share Posted August 17, 2002 just an intial impression of 'methylation' is it doesn't seem to be consistent, that is, it may not be that useful a way of organising ideas. 50mg is a huge dose of b vitamins. sot(slightly off topic) mot(massively off topic) tpd(total phase disjunction ) i notice people needing continuous probitics, i know that selenium is required by 'good' intestinal yeast and was thinking maybe there would be benefit in seleneometthionine being taken regularly to help nurture a benign stomach flora. tpd message boards are not very persistant, that is topics sorta come and go and opinions change, its not like a web site having the same thing up persistently.... the problems i have seen on message boards come where people or viewpoints have been excluded and naturally they want redress... if people have a grievance then it important to understand that redress is always avaliable by posting your thoughts on board if one has time to peruse a message board and take time to take offence from one post in a gazillion then there is time to post a reply to it.... > I tried to connect the dots of the recent thread and added a little > from a few sites. If anything new comes up, like finding the name of > the test to ask for, I will it and then this will be in the Files > section under Related Topics. It is very consistent with what we > have seen with people having phenol problems doing very badly on B6 > and DMG/TMG. In our family, I can note that my older son improved > some on Zolfot (increased serotonin) and terrible on DMG and one > multiple vitamin that had highER levels of all Bs at 50 mg/day. Kd. > > >>>>>>>>>>>>>>>>>> > > Pfeiffer identifies two different supplement regimes depending on if > you are an " overmethylator " or an " undermethylator. " > > Q: How can you find out if you are over or under? > A: Histamine levels may be a good indicator of whether your child is > an over or under-methylator. > > Low histamine points to Overmethylator: If your child's histamine > level is low he is probably an over-methylator (according to > Pfeiffer research). This means that many supplements would be > detrimental to him (those containing methyl). These would include > taurine, GABA [both precursors to methyl activity in the brain], > folic acid, B12, B6, DMG, TMG (and SAMe) - to name a few. > > From the Pfeiffer site http://www.hriptc.org/BioTreatment.html in > regard to depression and neurotransmitters: > High-histamine depressives overproduce and retain excessive levels > of histamine, an important neurotransmitter which affects human > behavior. They are under-methylated resulting in generalized low > levels of important neurotransmitters such as serotonin. This > syndrome often involves seasonal variations in depression, obsessive- > compulsive behavior, inhalant allergies, and frequent headaches. > Biochemical treatment revolves around antifolates, especially > calcium and methionine. > Low-histamine depressives are usually nervous, anxious individuals > who are prone to paranoia and despair. They are over-methylated > which results in elevated dopamine and norepinephrine levels. > Although free of seasonal allergies, they often report a multitude > of food and chemical sensitivities. Many have a history of > hyperactivity, learning disabilities, and underachievement. > Treatment focuses on use of folic acid together with niacinamide and > vitamin B-12, with about 2-4 months required for correction of the > imbalance. > > Q: What test checks histamine levels? > A: There is a blood test to measure histamine. Your pediatrician > can do it. > > Q: How can I lower the histamine level? > A: Some people, who have trouble converting sulfur to sulphate (PST > issue), and who have a sensitivity to foods because of this, often > times develop a high histamine level. My son develops a runny nose > as a reaction to this problem. Benadryl helps my son with this, and > anything else that lowers histamine would help him, also. I think > the Feingold Diet, No-Fenol, or avoiding certain phenolic and high > salicylate foods may help the sulfation problem and subsequently > lower the high histamine level. Benadryl and Pepcid AC are histamine > blockers. This might explain why Pepcid AC is so effective on some > kids. A few parents have reported that a histamine reaction with > certain foods did not happen when No-Fenol was given with those > foods. > > Q: What amount of B6 is considered " high " ? > A: From the site http://www.methylmagic.com/faq.html > Some supplements have lots of B6 (e.g. 100mg) and the author usually > aims for between 20 and 50mg per day of B6. Excess niacin (B3) is > metabolized by methylation and thus uses up methyl groups. Also aim > for 50 mg or less. These values are likely for an adult so a child > needs much less. Quote Link to comment Share on other sites More sharing options...
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