Guest guest Posted March 31, 2003 Report Share Posted March 31, 2003 I was on Vioxx for 6 months with no luck. I didn't find that it helped me with anything. BUT that is why there are so many different drugs out there..everyone is different. I think it is GREAT if it helps you. Unfortunately the only thing I have found for relief is Morphine. I fought going on this for over a year, but after everything else failed I finally had to give in. Vioxx has to be soooo much better for your system than morphine. Becker in MO Vioxx > Has anyone taken Vioxx and found it helpful with headaches? I've taken it for a week for hip/leg pain- helped that a lot, but also had a good headache week. > Thanks, > in VA > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 31, 2003 Report Share Posted March 31, 2003 I was on Vioxx for 6 months with no luck. I didn't find that it helped me with anything. BUT that is why there are so many different drugs out there..everyone is different. I think it is GREAT if it helps you. Unfortunately the only thing I have found for relief is Morphine. I fought going on this for over a year, but after everything else failed I finally had to give in. Vioxx has to be soooo much better for your system than morphine. Becker in MO Vioxx > Has anyone taken Vioxx and found it helpful with headaches? I've taken it for a week for hip/leg pain- helped that a lot, but also had a good headache week. > Thanks, > in VA > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 31, 2003 Report Share Posted March 31, 2003 I was on Vioxx for 6 months with no luck. I didn't find that it helped me with anything. BUT that is why there are so many different drugs out there..everyone is different. I think it is GREAT if it helps you. Unfortunately the only thing I have found for relief is Morphine. I fought going on this for over a year, but after everything else failed I finally had to give in. Vioxx has to be soooo much better for your system than morphine. Becker in MO Vioxx > Has anyone taken Vioxx and found it helpful with headaches? I've taken it for a week for hip/leg pain- helped that a lot, but also had a good headache week. > Thanks, > in VA > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Joyce, Thanks for the information on Vioxx. The website you referred to did not come through on the message. I've been weening myself off of it. What are other peoples experience with anti-inflammatories, i.e. when have people been successful with stopping to take them? Fred Gross, C2K, 1/21/04 > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > Information taken off the internet, see website below. > > Arthritis affects around 40 million Americans, causing pain and joint > deterioration. > > VIOXX is Merck's second largest-selling medicine, and it is this fact that > leaves Merck in the middle of 4 federal > lawsuits, a number of state lawsuits, individual claims, and class actions. > The FDA issued a " Warning Letter " to > Merck on September 17, 2001 to cease certain marketing efforts because > their promotional activities and materials > are " false, lacking in fair balance, or otherwise misleading in violation > of the Federal Food, Drug, and Cosmetic > Act and applicable regulations " . > The letter went on to say that " You have engaged in a promotional campaign > for VIOXX that minimizes the potentially > serious cardiovascular findings that were observed in the Vioxx > Gastrointestinal Outcomes Research, " referring > to the allegations that link the drug to problems like heart attacks, > stroke, sudden death, and blood clots. > The warning letter indicates that Merck has previously upset regulators. > Cardiovascular problems, such as heart attacks, stroke , sudden death and > blood clots has been linked to the use of > VIOXX. Patients who already have heart disease should be even more > conscious of the effects VIOXX can have > on their health. An analysis published in the Journal of American Medicine > studied the side affects of patients > taking VIOXX. Those included in the study seemed to have double the risk of > cardiovascular problems. > The government has ordered Merck & Co. to cease promotions aimed to get > doctors to prescribe its blockbuster > arthritis painkiller VIOXX, saying they minimize potential safety risks. > Three prominent patient advocacy groups have urged Merck & Co. and Parmacia > Corp. to test whether their hotselling > arthritis drugs increase the risk of heart attack and stroke, but the U.S. > drugmakers said they remain unconvinced > such safety trials are warranted. > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Joyce, Fred...Intersting article on Vioxx....I personally experienced an allergic reaction to Vioxx...tingling lips....I'm not making this up....I so disbelieved it that I took another several months later only to get...yes...tingling lips once again! I think I have tried every anti-inflammatory drug that exists...because I am married to an internal medicine physician(the very one who is making me prove by way of scientific articles that hip resurfacing is a valid procedure) who gets free samples of everything...especially the new ones. My husband and son LOVE Vioxx and use it after big workouts...they both run marathons. I actually prefer not to take anything but honestly...sometimes I have to...like today...with rain...and when I do I really just take anything else we happen to have a sample of that's not in the Vioxx/Bextra class. Fred if I were you I'd just do what you're doing...ween yourself off...every other day, twice a week and then only when you're desperate....do you take Glucosamine- Chondroitin? I personally think that nothing is better....unless it rains again tomorrow. I sure don't think I'll be running any marathons anytime soon! Susie -- In surfacehippy , " steelhead_fred " wrote: > Joyce, > Thanks for the information on Vioxx. The website you referred to > did not come through on the message. I've been weening myself off > of it. What are other peoples experience with anti-inflammatories, > i.e. when have people been successful with stopping to take them? > Fred > Gross, C2K, 1/21/04 > > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > Information taken off the internet, see website below. > > > > Arthritis affects around 40 million Americans, causing pain and > joint > > deterioration. > > > > VIOXX is Merck's second largest-selling medicine, and it is this > fact that > > leaves Merck in the middle of 4 federal > > lawsuits, a number of state lawsuits, individual claims, and class > actions. > > The FDA issued a " Warning Letter " to > > Merck on September 17, 2001 to cease certain marketing efforts > because > > their promotional activities and materials > > are " false, lacking in fair balance, or otherwise misleading in > violation > > of the Federal Food, Drug, and Cosmetic > > Act and applicable regulations " . > > The letter went on to say that " You have engaged in a promotional > campaign > > for VIOXX that minimizes the potentially > > serious cardiovascular findings that were observed in the Vioxx > > Gastrointestinal Outcomes Research, " referring > > to the allegations that link the drug to problems like heart > attacks, > > stroke, sudden death, and blood clots. > > The warning letter indicates that Merck has previously upset > regulators. > > Cardiovascular problems, such as heart attacks, stroke , sudden > death and > > blood clots has been linked to the use of > > VIOXX. Patients who already have heart disease should be even more > > conscious of the effects VIOXX can have > > on their health. An analysis published in the Journal of American > Medicine > > studied the side affects of patients > > taking VIOXX. Those included in the study seemed to have double > the risk of > > cardiovascular problems. > > The government has ordered Merck & Co. to cease promotions aimed > to get > > doctors to prescribe its blockbuster > > arthritis painkiller VIOXX, saying they minimize potential safety > risks. > > Three prominent patient advocacy groups have urged Merck & Co. and > Parmacia > > Corp. to test whether their hotselling > > arthritis drugs increase the risk of heart attack and stroke, but > the U.S. > > drugmakers said they remain unconvinced > > such safety trials are warranted. > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Joyce, Fred...also...it could very well be that some penniless attorney is trying to drum up a class action law suit...Susie -- In surfacehippy , " Joyce Graves " wrote: > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > Information taken off the internet, see website below. > > Arthritis affects around 40 million Americans, causing pain and joint > deterioration. > > VIOXX is Merck's second largest-selling medicine, and it is this fact that > leaves Merck in the middle of 4 federal > lawsuits, a number of state lawsuits, individual claims, and class actions. > The FDA issued a " Warning Letter " to > Merck on September 17, 2001 to cease certain marketing efforts because > their promotional activities and materials > are " false, lacking in fair balance, or otherwise misleading in violation > of the Federal Food, Drug, and Cosmetic > Act and applicable regulations " . > The letter went on to say that " You have engaged in a promotional campaign > for VIOXX that minimizes the potentially > serious cardiovascular findings that were observed in the Vioxx > Gastrointestinal Outcomes Research, " referring > to the allegations that link the drug to problems like heart attacks, > stroke, sudden death, and blood clots. > The warning letter indicates that Merck has previously upset regulators. > Cardiovascular problems, such as heart attacks, stroke , sudden death and > blood clots has been linked to the use of > VIOXX. Patients who already have heart disease should be even more > conscious of the effects VIOXX can have > on their health. An analysis published in the Journal of American Medicine > studied the side affects of patients > taking VIOXX. Those included in the study seemed to have double the risk of > cardiovascular problems. > The government has ordered Merck & Co. to cease promotions aimed to get > doctors to prescribe its blockbuster > arthritis painkiller VIOXX, saying they minimize potential safety risks. > Three prominent patient advocacy groups have urged Merck & Co. and Parmacia > Corp. to test whether their hotselling > arthritis drugs increase the risk of heart attack and stroke, but the U.S. > drugmakers said they remain unconvinced > such safety trials are warranted. > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Joyce, Fred...also...it could very well be that some penniless attorney is trying to drum up a class action law suit...Susie -- In surfacehippy , " Joyce Graves " wrote: > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > Information taken off the internet, see website below. > > Arthritis affects around 40 million Americans, causing pain and joint > deterioration. > > VIOXX is Merck's second largest-selling medicine, and it is this fact that > leaves Merck in the middle of 4 federal > lawsuits, a number of state lawsuits, individual claims, and class actions. > The FDA issued a " Warning Letter " to > Merck on September 17, 2001 to cease certain marketing efforts because > their promotional activities and materials > are " false, lacking in fair balance, or otherwise misleading in violation > of the Federal Food, Drug, and Cosmetic > Act and applicable regulations " . > The letter went on to say that " You have engaged in a promotional campaign > for VIOXX that minimizes the potentially > serious cardiovascular findings that were observed in the Vioxx > Gastrointestinal Outcomes Research, " referring > to the allegations that link the drug to problems like heart attacks, > stroke, sudden death, and blood clots. > The warning letter indicates that Merck has previously upset regulators. > Cardiovascular problems, such as heart attacks, stroke , sudden death and > blood clots has been linked to the use of > VIOXX. Patients who already have heart disease should be even more > conscious of the effects VIOXX can have > on their health. An analysis published in the Journal of American Medicine > studied the side affects of patients > taking VIOXX. Those included in the study seemed to have double the risk of > cardiovascular problems. > The government has ordered Merck & Co. to cease promotions aimed to get > doctors to prescribe its blockbuster > arthritis painkiller VIOXX, saying they minimize potential safety risks. > Three prominent patient advocacy groups have urged Merck & Co. and Parmacia > Corp. to test whether their hotselling > arthritis drugs increase the risk of heart attack and stroke, but the U.S. > drugmakers said they remain unconvinced > such safety trials are warranted. > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Thanks Susie, Do you know what was going on with your blood pressure when you experienced your side effects to Vioxx? Did it make you hyper? I think this shows that we should get off of whatever drugs we're taking as soon as we can tolerate it. Regardless of how we feel now or the side effects we're enduring, we just don't know what the long term effects are. I took Glucosamine-Chondroitin about a year ago but I'm not really sure it had an affect on the pain (I was taking Vioxx and acetominaphen also). I think it reversed or slowed the deterioration of my other hip (non-operative). An x-ray that I had post op seemed to show that there was more cartilidge in my non-op hip than and x-ray prior to taking Glucosamine-Chondroitin. I've been told that it cannot reverse the deterioration. I'm not a radiologist so perhaps I misread the x-rays. Fred Gross, C2K 1/21/04 > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > > > Information taken off the internet, see website below. > > > > > > Arthritis affects around 40 million Americans, causing pain and > > joint > > > deterioration. > > > > > > VIOXX is Merck's second largest-selling medicine, and it is this > > fact that > > > leaves Merck in the middle of 4 federal > > > lawsuits, a number of state lawsuits, individual claims, and > class > > actions. > > > The FDA issued a " Warning Letter " to > > > Merck on September 17, 2001 to cease certain marketing efforts > > because > > > their promotional activities and materials > > > are " false, lacking in fair balance, or otherwise misleading in > > violation > > > of the Federal Food, Drug, and Cosmetic > > > Act and applicable regulations " . > > > The letter went on to say that " You have engaged in a promotional > > campaign > > > for VIOXX that minimizes the potentially > > > serious cardiovascular findings that were observed in the Vioxx > > > Gastrointestinal Outcomes Research, " referring > > > to the allegations that link the drug to problems like heart > > attacks, > > > stroke, sudden death, and blood clots. > > > The warning letter indicates that Merck has previously upset > > regulators. > > > Cardiovascular problems, such as heart attacks, stroke , sudden > > death and > > > blood clots has been linked to the use of > > > VIOXX. Patients who already have heart disease should be even more > > > conscious of the effects VIOXX can have > > > on their health. An analysis published in the Journal of American > > Medicine > > > studied the side affects of patients > > > taking VIOXX. Those included in the study seemed to have double > > the risk of > > > cardiovascular problems. > > > The government has ordered Merck & Co. to cease promotions aimed > > to get > > > doctors to prescribe its blockbuster > > > arthritis painkiller VIOXX, saying they minimize potential safety > > risks. > > > Three prominent patient advocacy groups have urged Merck & Co. > and > > Parmacia > > > Corp. to test whether their hotselling > > > arthritis drugs increase the risk of heart attack and stroke, but > > the U.S. > > > drugmakers said they remain unconvinced > > > such safety trials are warranted. > > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Heigh there, high there, ho there... Vioxx and Celebrex are two in a new class of NSAID's (for all I know, it may only be a class of two) called x-2 inhibiters. If I've read the journals right (and I'm not a doctor, only in interesting in having some control of my medical destiny), their primary appeal was in not eroding the esophagus and otherwise torching the digestive system. The most recent articles I've read suggest that even that benefit may apply only a limited number of cases. But...consider this possibility (and not because I don't like lawyers): Every drug will have negative side effects in a small percentage of the target population. The drug companies' own informational sheets make that clear. But when only a few thousand people are taking a drug, only a tiny handful will suffer the negative results. That number is waaaay under a lawyer's radar screen. Once the new drug gets into the millions of patients (and with 40-million arthitis suffers, that's quite possible), the percentage stays the same, but the target number for lawyers goes way up. If one per cent of the people taking a drug have problems, and 30,000 people are taking the drug, that means possible problems for, what, about 300 people if I do the math right (and please correct me, if I don't). And the final number will certainly be smaller. Now let's suppose the number of people taking a drug (as in the case of the x-2 items) jumps to, say, 3,000,000... all of a sudden a lawyer with time on his/her hands, has a sizable client base. All he/she needs to do is advertise -- or post on the internet -- and, son of a gun -- a good drug for many becomes a rich target for a lawsuit. Just some thoughts. Also: When I first hurt the hip that now requires resurfacing, I was prescribed 800 mg of Ibuprofin three times a day. Forget liver and kidney issues (which, at those dosages can be worrisome) consider that my esophagus constantly felt like somebody had been using it to light stove matches. When I asked the prescribing doc, he told me the max safe daily intake was 3200 mg...so I had a ways to go, if I needed more. (Oh yeah!) Sometimes it's the drug, sometimes it's the drug maker, sometimes it's the doc...and sometimes, the randomness of the universe just comes and gets you. Alan @y...> wrote: > Joyce, Fred...also...it could very well be that some penniless > attorney is trying to drum up a class action law suit...Susie > > > -- In surfacehippy , " Joyce Graves " > wrote: > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > Information taken off the internet, see website below. > > > > Arthritis affects around 40 million Americans, causing pain and > joint > > deterioration. > > > > VIOXX is Merck's second largest-selling medicine, and it is this > fact that > > leaves Merck in the middle of 4 federal > > lawsuits, a number of state lawsuits, individual claims, and class > actions. > > The FDA issued a " Warning Letter " to > > Merck on September 17, 2001 to cease certain marketing efforts > because > > their promotional activities and materials > > are " false, lacking in fair balance, or otherwise misleading in > violation > > of the Federal Food, Drug, and Cosmetic > > Act and applicable regulations " . > > The letter went on to say that " You have engaged in a promotional > campaign > > for VIOXX that minimizes the potentially > > serious cardiovascular findings that were observed in the Vioxx > > Gastrointestinal Outcomes Research, " referring > > to the allegations that link the drug to problems like heart > attacks, > > stroke, sudden death, and blood clots. > > The warning letter indicates that Merck has previously upset > regulators. > > Cardiovascular problems, such as heart attacks, stroke , sudden > death and > > blood clots has been linked to the use of > > VIOXX. Patients who already have heart disease should be even more > > conscious of the effects VIOXX can have > > on their health. An analysis published in the Journal of American > Medicine > > studied the side affects of patients > > taking VIOXX. Those included in the study seemed to have double the > risk of > > cardiovascular problems. > > The government has ordered Merck & Co. to cease promotions aimed to > get > > doctors to prescribe its blockbuster > > arthritis painkiller VIOXX, saying they minimize potential safety > risks. > > Three prominent patient advocacy groups have urged Merck & Co. and > Parmacia > > Corp. to test whether their hotselling > > arthritis drugs increase the risk of heart attack and stroke, but > the U.S. > > drugmakers said they remain unconvinced > > such safety trials are warranted. > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Fred...I know about the Vioxx association with high blood pressure and I sure would be a good test case with my lips but then again I'd just as soon not have a stroke. I'm guessing it probably did make my blood pressure rise. I typically have very low blood pressure. It did not make me hyper. I went to a continuing education conference several months ago titled " The Emerging Epidemic of Bone and Joint Disease " ...that might not be the exact title but anyway it was presented by a very nteresting, knowledgeable PhD. person and attended by pharmacists, nurses, therapists, nutritionissts, etc. This speaker gave an overview of ..duh..bone and joint diseases but she went into all of the various treatments for specific disorders and then threw in some alternative suggestions that she had personal experience with...she said an old Indian remedy for OA is nutmeg. Seriously...she said take three whole nutmeg and grind them up and put in a quart of water and take a sip a day. I've also heard that cod liver oil is helpful. Susie > > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > > > > > Information taken off the internet, see website below. > > > > > > > > Arthritis affects around 40 million Americans, causing pain > and > > > joint > > > > deterioration. > > > > > > > > VIOXX is Merck's second largest-selling medicine, and it is > this > > > fact that > > > > leaves Merck in the middle of 4 federal > > > > lawsuits, a number of state lawsuits, individual claims, and > > class > > > actions. > > > > The FDA issued a " Warning Letter " to > > > > Merck on September 17, 2001 to cease certain marketing efforts > > > because > > > > their promotional activities and materials > > > > are " false, lacking in fair balance, or otherwise misleading > in > > > violation > > > > of the Federal Food, Drug, and Cosmetic > > > > Act and applicable regulations " . > > > > The letter went on to say that " You have engaged in a > promotional > > > campaign > > > > for VIOXX that minimizes the potentially > > > > serious cardiovascular findings that were observed in the Vioxx > > > > Gastrointestinal Outcomes Research, " referring > > > > to the allegations that link the drug to problems like heart > > > attacks, > > > > stroke, sudden death, and blood clots. > > > > The warning letter indicates that Merck has previously upset > > > regulators. > > > > Cardiovascular problems, such as heart attacks, stroke , > sudden > > > death and > > > > blood clots has been linked to the use of > > > > VIOXX. Patients who already have heart disease should be even > more > > > > conscious of the effects VIOXX can have > > > > on their health. An analysis published in the Journal of > American > > > Medicine > > > > studied the side affects of patients > > > > taking VIOXX. Those included in the study seemed to have > double > > > the risk of > > > > cardiovascular problems. > > > > The government has ordered Merck & Co. to cease promotions > aimed > > > to get > > > > doctors to prescribe its blockbuster > > > > arthritis painkiller VIOXX, saying they minimize potential > safety > > > risks. > > > > Three prominent patient advocacy groups have urged Merck & Co. > > and > > > Parmacia > > > > Corp. to test whether their hotselling > > > > arthritis drugs increase the risk of heart attack and stroke, > but > > > the U.S. > > > > drugmakers said they remain unconvinced > > > > such safety trials are warranted. > > > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Fred...I know about the Vioxx association with high blood pressure and I sure would be a good test case with my lips but then again I'd just as soon not have a stroke. I'm guessing it probably did make my blood pressure rise. I typically have very low blood pressure. It did not make me hyper. I went to a continuing education conference several months ago titled " The Emerging Epidemic of Bone and Joint Disease " ...that might not be the exact title but anyway it was presented by a very nteresting, knowledgeable PhD. person and attended by pharmacists, nurses, therapists, nutritionissts, etc. This speaker gave an overview of ..duh..bone and joint diseases but she went into all of the various treatments for specific disorders and then threw in some alternative suggestions that she had personal experience with...she said an old Indian remedy for OA is nutmeg. Seriously...she said take three whole nutmeg and grind them up and put in a quart of water and take a sip a day. I've also heard that cod liver oil is helpful. Susie > > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > > > > > Information taken off the internet, see website below. > > > > > > > > Arthritis affects around 40 million Americans, causing pain > and > > > joint > > > > deterioration. > > > > > > > > VIOXX is Merck's second largest-selling medicine, and it is > this > > > fact that > > > > leaves Merck in the middle of 4 federal > > > > lawsuits, a number of state lawsuits, individual claims, and > > class > > > actions. > > > > The FDA issued a " Warning Letter " to > > > > Merck on September 17, 2001 to cease certain marketing efforts > > > because > > > > their promotional activities and materials > > > > are " false, lacking in fair balance, or otherwise misleading > in > > > violation > > > > of the Federal Food, Drug, and Cosmetic > > > > Act and applicable regulations " . > > > > The letter went on to say that " You have engaged in a > promotional > > > campaign > > > > for VIOXX that minimizes the potentially > > > > serious cardiovascular findings that were observed in the Vioxx > > > > Gastrointestinal Outcomes Research, " referring > > > > to the allegations that link the drug to problems like heart > > > attacks, > > > > stroke, sudden death, and blood clots. > > > > The warning letter indicates that Merck has previously upset > > > regulators. > > > > Cardiovascular problems, such as heart attacks, stroke , > sudden > > > death and > > > > blood clots has been linked to the use of > > > > VIOXX. Patients who already have heart disease should be even > more > > > > conscious of the effects VIOXX can have > > > > on their health. An analysis published in the Journal of > American > > > Medicine > > > > studied the side affects of patients > > > > taking VIOXX. Those included in the study seemed to have > double > > > the risk of > > > > cardiovascular problems. > > > > The government has ordered Merck & Co. to cease promotions > aimed > > > to get > > > > doctors to prescribe its blockbuster > > > > arthritis painkiller VIOXX, saying they minimize potential > safety > > > risks. > > > > Three prominent patient advocacy groups have urged Merck & Co. > > and > > > Parmacia > > > > Corp. to test whether their hotselling > > > > arthritis drugs increase the risk of heart attack and stroke, > but > > > the U.S. > > > > drugmakers said they remain unconvinced > > > > such safety trials are warranted. > > > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Hi Susie, I too sometimes get that funny tingly stuff around lips with things like Celebrex, Asprin etc......... I have taken it that somehow it plays with the nervous system and affects it temporarily just after it hits the system.............. As for the reports on Vioxx........ I know my GP sister told me recently that the cardiologists are less than impressed by Celebrex and how it is impacting on a few too many hearts............ I also know that my fathers doctors have said that it is too dangerous for him to take at 88 because of reported side effects on hearts.......... I figure if it is too dangerous at that age I wouldn't want to be taking too much of it at 55............ Thankfully since the resurface all that medication is in the past............ And with the emerging epidemic of Bone and Joint disease, sadly I suspect much of that could be laid at the feet of not enough appropriate exercise and people grinding joints without looking first at their gaits to pick up possible problems............. and really we do have to get away from thinking the only way to fix these things is take a pill, eat a herb etc............ i.e. quick fix drug mentality that has pervaded all varieties of medicine including 'natural' therepies.............. We were made to move, our joints require strong muscles to support them and get good gaps for synovial fluids................. How many have that??? Edith LBHR Dr. L Walter Syd Aust 8/02 > Fred...I know about the Vioxx association with high blood pressure > and I sure would be a good test case with my lips but then again I'd > just as soon not have a stroke. I'm guessing it probably did make my > blood pressure rise. I typically have very low blood pressure. It > did not make me hyper. I went to a continuing education conference > several months ago titled " The Emerging Epidemic of Bone and Joint > Disease " ...that might not be the exact title but anyway it was > presented by a very nteresting, knowledgeable PhD. person and > attended by pharmacists, nurses, therapists, nutritionissts, etc. > This speaker gave an overview of ..duh..bone and joint diseases but > she went into all of the various treatments for specific disorders > and then threw in some alternative suggestions that she had personal > experience with...she said an old Indian remedy for OA is nutmeg. > Seriously...she said take three whole nutmeg and grind them up and > put in a quart of water and take a sip a day. I've also heard that > cod liver oil is helpful. Susie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Hi Susie, I too sometimes get that funny tingly stuff around lips with things like Celebrex, Asprin etc......... I have taken it that somehow it plays with the nervous system and affects it temporarily just after it hits the system.............. As for the reports on Vioxx........ I know my GP sister told me recently that the cardiologists are less than impressed by Celebrex and how it is impacting on a few too many hearts............ I also know that my fathers doctors have said that it is too dangerous for him to take at 88 because of reported side effects on hearts.......... I figure if it is too dangerous at that age I wouldn't want to be taking too much of it at 55............ Thankfully since the resurface all that medication is in the past............ And with the emerging epidemic of Bone and Joint disease, sadly I suspect much of that could be laid at the feet of not enough appropriate exercise and people grinding joints without looking first at their gaits to pick up possible problems............. and really we do have to get away from thinking the only way to fix these things is take a pill, eat a herb etc............ i.e. quick fix drug mentality that has pervaded all varieties of medicine including 'natural' therepies.............. We were made to move, our joints require strong muscles to support them and get good gaps for synovial fluids................. How many have that??? Edith LBHR Dr. L Walter Syd Aust 8/02 > Fred...I know about the Vioxx association with high blood pressure > and I sure would be a good test case with my lips but then again I'd > just as soon not have a stroke. I'm guessing it probably did make my > blood pressure rise. I typically have very low blood pressure. It > did not make me hyper. I went to a continuing education conference > several months ago titled " The Emerging Epidemic of Bone and Joint > Disease " ...that might not be the exact title but anyway it was > presented by a very nteresting, knowledgeable PhD. person and > attended by pharmacists, nurses, therapists, nutritionissts, etc. > This speaker gave an overview of ..duh..bone and joint diseases but > she went into all of the various treatments for specific disorders > and then threw in some alternative suggestions that she had personal > experience with...she said an old Indian remedy for OA is nutmeg. > Seriously...she said take three whole nutmeg and grind them up and > put in a quart of water and take a sip a day. I've also heard that > cod liver oil is helpful. Susie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Fred: I am unclear why you are taking an anti-inflammatory. I was under the impression that after the resurf, that one no longer needed to take them. I had to stop mine 2 weeks prior to surgery, then I never took them again. I did take mild pain killers for a bit, then Tylenol. How come you are still taking them if your surgery was this past January? Lois C+ 3/27/03 Dr.Mont Re: Vioxx Joyce, Thanks for the information on Vioxx. The website you referred to did not come through on the message. I've been weening myself off of it. What are other peoples experience with anti-inflammatories, i.e. when have people been successful with stopping to take them? Fred Gross, C2K, 1/21/04 > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > Information taken off the internet, see website below. > > Arthritis affects around 40 million Americans, causing pain and joint > deterioration. > > VIOXX is Merck's second largest-selling medicine, and it is this fact that > leaves Merck in the middle of 4 federal > lawsuits, a number of state lawsuits, individual claims, and class actions. > The FDA issued a " Warning Letter " to > Merck on September 17, 2001 to cease certain marketing efforts because > their promotional activities and materials > are " false, lacking in fair balance, or otherwise misleading in violation > of the Federal Food, Drug, and Cosmetic > Act and applicable regulations " . > The letter went on to say that " You have engaged in a promotional campaign > for VIOXX that minimizes the potentially > serious cardiovascular findings that were observed in the Vioxx > Gastrointestinal Outcomes Research, " referring > to the allegations that link the drug to problems like heart attacks, > stroke, sudden death, and blood clots. > The warning letter indicates that Merck has previously upset regulators. > Cardiovascular problems, such as heart attacks, stroke , sudden death and > blood clots has been linked to the use of > VIOXX. Patients who already have heart disease should be even more > conscious of the effects VIOXX can have > on their health. An analysis published in the Journal of American Medicine > studied the side affects of patients > taking VIOXX. Those included in the study seemed to have double the risk of > cardiovascular problems. > The government has ordered Merck & Co. to cease promotions aimed to get > doctors to prescribe its blockbuster > arthritis painkiller VIOXX, saying they minimize potential safety risks. > Three prominent patient advocacy groups have urged Merck & Co. and Parmacia > Corp. to test whether their hotselling > arthritis drugs increase the risk of heart attack and stroke, but the U.S. > drugmakers said they remain unconvinced > such safety trials are warranted. > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Lois, If I remember correctly, I was instructed to take Vioxx the morning of the surgery. After surgery the dose was doubled to 50 mg for two to three weeks then back to 25 mg per day. Even now I notice that the area around my hip and the muscles in my thigh feel better when I take the Vioxx than when I don't. As I said earlier, I am not taking it every day. I'll go three or four days sometimes without taking it. I am walking a little over 2 miles a day and doing the exercises perscribed by Dr. Gross. I feel like I'm ready for the next level of exercise but there is still what I refer to as surgical pain, although it is less and less every week. I'll check with Lee Webb or Dr. Gross to see what they say about the Vioxx. Fred Gross, C2K 1/21/04 > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > Information taken off the internet, see website below. > > > > Arthritis affects around 40 million Americans, causing pain and > joint > > deterioration. > > > > VIOXX is Merck's second largest-selling medicine, and it is this > fact that > > leaves Merck in the middle of 4 federal > > lawsuits, a number of state lawsuits, individual claims, and class > actions. > > The FDA issued a " Warning Letter " to > > Merck on September 17, 2001 to cease certain marketing efforts > because > > their promotional activities and materials > > are " false, lacking in fair balance, or otherwise misleading in > violation > > of the Federal Food, Drug, and Cosmetic > > Act and applicable regulations " . > > The letter went on to say that " You have engaged in a promotional > campaign > > for VIOXX that minimizes the potentially > > serious cardiovascular findings that were observed in the Vioxx > > Gastrointestinal Outcomes Research, " referring > > to the allegations that link the drug to problems like heart > attacks, > > stroke, sudden death, and blood clots. > > The warning letter indicates that Merck has previously upset > regulators. > > Cardiovascular problems, such as heart attacks, stroke , sudden > death and > > blood clots has been linked to the use of > > VIOXX. Patients who already have heart disease should be even more > > conscious of the effects VIOXX can have > > on their health. An analysis published in the Journal of American > Medicine > > studied the side affects of patients > > taking VIOXX. Those included in the study seemed to have double > the risk of > > cardiovascular problems. > > The government has ordered Merck & Co. to cease promotions aimed > to get > > doctors to prescribe its blockbuster > > arthritis painkiller VIOXX, saying they minimize potential safety > risks. > > Three prominent patient advocacy groups have urged Merck & Co. and > Parmacia > > Corp. to test whether their hotselling > > arthritis drugs increase the risk of heart attack and stroke, but > the U.S. > > drugmakers said they remain unconvinced > > such safety trials are warranted. > > VIOXX AND CELEBREX LEGAL HELP > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Lois, If I remember correctly, I was instructed to take Vioxx the morning of the surgery. After surgery the dose was doubled to 50 mg for two to three weeks then back to 25 mg per day. Even now I notice that the area around my hip and the muscles in my thigh feel better when I take the Vioxx than when I don't. As I said earlier, I am not taking it every day. I'll go three or four days sometimes without taking it. I am walking a little over 2 miles a day and doing the exercises perscribed by Dr. Gross. I feel like I'm ready for the next level of exercise but there is still what I refer to as surgical pain, although it is less and less every week. I'll check with Lee Webb or Dr. Gross to see what they say about the Vioxx. Fred Gross, C2K 1/21/04 > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > Information taken off the internet, see website below. > > > > Arthritis affects around 40 million Americans, causing pain and > joint > > deterioration. > > > > VIOXX is Merck's second largest-selling medicine, and it is this > fact that > > leaves Merck in the middle of 4 federal > > lawsuits, a number of state lawsuits, individual claims, and class > actions. > > The FDA issued a " Warning Letter " to > > Merck on September 17, 2001 to cease certain marketing efforts > because > > their promotional activities and materials > > are " false, lacking in fair balance, or otherwise misleading in > violation > > of the Federal Food, Drug, and Cosmetic > > Act and applicable regulations " . > > The letter went on to say that " You have engaged in a promotional > campaign > > for VIOXX that minimizes the potentially > > serious cardiovascular findings that were observed in the Vioxx > > Gastrointestinal Outcomes Research, " referring > > to the allegations that link the drug to problems like heart > attacks, > > stroke, sudden death, and blood clots. > > The warning letter indicates that Merck has previously upset > regulators. > > Cardiovascular problems, such as heart attacks, stroke , sudden > death and > > blood clots has been linked to the use of > > VIOXX. Patients who already have heart disease should be even more > > conscious of the effects VIOXX can have > > on their health. An analysis published in the Journal of American > Medicine > > studied the side affects of patients > > taking VIOXX. Those included in the study seemed to have double > the risk of > > cardiovascular problems. > > The government has ordered Merck & Co. to cease promotions aimed > to get > > doctors to prescribe its blockbuster > > arthritis painkiller VIOXX, saying they minimize potential safety > risks. > > Three prominent patient advocacy groups have urged Merck & Co. and > Parmacia > > Corp. to test whether their hotselling > > arthritis drugs increase the risk of heart attack and stroke, but > the U.S. > > drugmakers said they remain unconvinced > > such safety trials are warranted. > > VIOXX AND CELEBREX LEGAL HELP > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2004 Report Share Posted May 13, 2004 See a copy of the article published in the April 2004 issue of the Arthritis Today – a non-commercial UK magazine reporting research treatment and education related to arthritis: COX-2 drugs to have stronger warnings on labelling Stronger warnings are to be added to the labelling of the mass-selling COX-2 drugs, after a safety review by the European body responsible for drug safety. The European Medicines Evaluation Agency in London launched the safety review in July last year after a request by the French health authority. The EMEA said the review would be carried out " because of safety concerns relating to the frequency of gastrointestinal and cardio-vascular adverse events. " One of the EMEA's options would have been to ban the drugs on safety grounds. But after concluding its review, the EMEA concluded that " the benefit-risk balance for these products remained positive for its target patient populations. " However, to promote the safe use of COX-2s, the EMEA recommended adding or strengthening warnings, in particular recommending caution for patients with underlying gastrointestinal and cardiovascular risks. It also recommended adding or modifying warnings concerning the risk of severe skin and hypersensitivity reactions. The new class of anti-inflammatory drugs were launched four years ago for pain relief in rheumatoid and osteoarthritis. Celecoxib (Celebrex) and rofecoxib(Vioxx) have become huge sellers, heavily marketed in the US and Europe as having fewer gastro-intestinal side effects than traditional NSAIDs. They have now been joined by etoricoxib (Arcoxia) and valde-coxib (Bextra). However, doubts persisted about some of the claims made by manufacturers, and when NICE approved COX-2s for use, the government's health advisory body was sufficiently concerned to issue a ruling advising doctors to exercise caution in prescribing COX-2s for patients with pre-existing heart conditions. Arthritis Today is published by The Arthritis Research Campaign (ARC), a research organisation entirely supported by voluntary contributions and legacies (verbatim quote – see www.arc.org.uk http://www.arc.org.uk/> ). Regards Dan * +44 (0)7974 981-407 * +44 (0)20 8501-2573 @ dan.milosevic@... _____ From: susettejk Sent: 13 May 2004 00:48 To: surfacehippy Subject: Re: Vioxx Joyce, Fred...Intersting article on Vioxx....I personally experienced an allergic reaction to Vioxx...tingling lips....I'm not making this up....I so disbelieved it that I took another several months later only to get...yes...tingling lips once again! I think I have tried every anti-inflammatory drug that exists...because I am married to an internal medicine physician(the very one who is making me prove by way of scientific articles that hip resurfacing is a valid procedure) who gets free samples of everything...especially the new ones. My husband and son LOVE Vioxx and use it after big workouts...they both run marathons. I actually prefer not to take anything but honestly...sometimes I have to...like today...with rain...and when I do I really just take anything else we happen to have a sample of that's not in the Vioxx/Bextra class. Fred if I were you I'd just do what you're doing...ween yourself off...every other day, twice a week and then only when you're desperate....do you take Glucosamine- Chondroitin? I personally think that nothing is better....unless it rains again tomorrow. I sure don't think I'll be running any marathons anytime soon! Susie -- In surfacehippy , " steelhead_fred " wrote: > Joyce, > Thanks for the information on Vioxx. The website you referred to > did not come through on the message. I've been weening myself off > of it. What are other peoples experience with anti-inflammatories, > i.e. when have people been successful with stopping to take them? > Fred > Gross, C2K, 1/21/04 > > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > Information taken off the internet, see website below. > > > > Arthritis affects around 40 million Americans, causing pain and > joint > > deterioration. > > > > VIOXX is Merck's second largest-selling medicine, and it is this > fact that > > leaves Merck in the middle of 4 federal > > lawsuits, a number of state lawsuits, individual claims, and class > actions. > > The FDA issued a " Warning Letter " to > > Merck on September 17, 2001 to cease certain marketing efforts > because > > their promotional activities and materials > > are " false, lacking in fair balance, or otherwise misleading in > violation > > of the Federal Food, Drug, and Cosmetic > > Act and applicable regulations " . > > The letter went on to say that " You have engaged in a promotional > campaign > > for VIOXX that minimizes the potentially > > serious cardiovascular findings that were observed in the Vioxx > > Gastrointestinal Outcomes Research, " referring > > to the allegations that link the drug to problems like heart > attacks, > > stroke, sudden death, and blood clots. > > The warning letter indicates that Merck has previously upset > regulators. > > Cardiovascular problems, such as heart attacks, stroke , sudden > death and > > blood clots has been linked to the use of > > VIOXX. Patients who already have heart disease should be even more > > conscious of the effects VIOXX can have > > on their health. An analysis published in the Journal of American > Medicine > > studied the side affects of patients > > taking VIOXX. Those included in the study seemed to have double > the risk of > > cardiovascular problems. > > The government has ordered Merck & Co. to cease promotions aimed > to get > > doctors to prescribe its blockbuster > > arthritis painkiller VIOXX, saying they minimize potential safety > risks. > > Three prominent patient advocacy groups have urged Merck & Co. and > Parmacia > > Corp. to test whether their hotselling > > arthritis drugs increase the risk of heart attack and stroke, but > the U.S. > > drugmakers said they remain unconvinced > > such safety trials are warranted. > > VIOXX AND CELEBREX LEGAL HELP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2004 Report Share Posted May 13, 2004 Fred: Dr. Gross wanted me on Celebrex after surgery (for 30 days, I think) but when I broke out in hives we stopped it and I never took anything more. I just use Motrin every now and then when I overdo things. RC2K Dr. Gross 3/24/04 > > > I thought this was interesting. Joyce (Dr Gross, LHR, 2/2/04) > > > > > > Information taken off the internet, see website below. > > > > > > Arthritis affects around 40 million Americans, causing pain and > > joint > > > deterioration. > > > > > > VIOXX is Merck's second largest-selling medicine, and it is this > > fact that > > > leaves Merck in the middle of 4 federal > > > lawsuits, a number of state lawsuits, individual claims, and > class > > actions. > > > The FDA issued a " Warning Letter " to > > > Merck on September 17, 2001 to cease certain marketing efforts > > because > > > their promotional activities and materials > > > are " false, lacking in fair balance, or otherwise misleading in > > violation > > > of the Federal Food, Drug, and Cosmetic > > > Act and applicable regulations " . > > > The letter went on to say that " You have engaged in a promotional > > campaign > > > for VIOXX that minimizes the potentially > > > serious cardiovascular findings that were observed in the Vioxx > > > Gastrointestinal Outcomes Research, " referring > > > to the allegations that link the drug to problems like heart > > attacks, > > > stroke, sudden death, and blood clots. > > > The warning letter indicates that Merck has previously upset > > regulators. > > > Cardiovascular problems, such as heart attacks, stroke , sudden > > death and > > > blood clots has been linked to the use of > > > VIOXX. Patients who already have heart disease should be even > more > > > conscious of the effects VIOXX can have > > > on their health. An analysis published in the Journal of American > > Medicine > > > studied the side affects of patients > > > taking VIOXX. Those included in the study seemed to have double > > the risk of > > > cardiovascular problems. > > > The government has ordered Merck & Co. to cease promotions aimed > > to get > > > doctors to prescribe its blockbuster > > > arthritis painkiller VIOXX, saying they minimize potential safety > > risks. > > > Three prominent patient advocacy groups have urged Merck & Co. > and > > Parmacia > > > Corp. to test whether their hotselling > > > arthritis drugs increase the risk of heart attack and stroke, but > > the U.S. > > > drugmakers said they remain unconvinced > > > such safety trials are warranted. > > > VIOXX AND CELEBREX LEGAL HELP > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2004 Report Share Posted September 30, 2004 If anyone takes Vioxx - I was just made aware (from the company first hand) that it will be taken off of the market. If you haven't gotten any information on this yet you should contact your doctor so he can explain how you must stop taking it. You CANNOT just stop the pills. Mommy to 12/17/98 and Christian 1/30/04 Quote Link to comment Share on other sites More sharing options...
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