CoQ10 and potential drug interactions

[Guest guest]

I thought that some of you might be interested in possible drug

interactions with CoQ10...which I had never been told of. I was given

a booklet previous to minor surgery I had the other day, warning of

potential problems with combinations of foods, drugs and herbs.

Source is from RENAL NUTRITION FORUM, Summer 2001, Vol.20, No.3.

CoQ10: immunostimulant/cardiovascular diseases/periodontal disease

potential interactions: Statins (eg.lovastatin, cerivastain,

pravastatain, simvastatin, atoryvastatin, fluvastatin), gemfibrozil,

tricyclic antidepressants, (e.g., amitriptvline, notriptyline,

despramine), glyburide.

potential outcomes of interaction: Statins, gemfibrozil, tricyclic

antidepressants, and glyburide decreases endogenous levels of CoQ10.

Recommended actions: The significance of drug induced decreases in

endogenous CoQ10 levels is uncertain. Supplementation with CoQ10 or

increases in the current CoQ10 dosage are potential options to offset

this effect. Monitor INR values and adjust warfarin dose as necessary.

Hope that this info is valuable.

Gwen

mom to Austen GA2