Guest guest Posted December 13, 2001 Report Share Posted December 13, 2001 Kirkman Labs has a few new articles online concerning enzymes and probiotics: http://www.kirkmanlabs.com/products/articles/Enzyme & Probiotics/index. htm 1. Autism-Dysbiosis-Probiotics - very short 2. Probiotics Role in GI Health - very long; a thorough description of probiotic strains and functions 3. Research on Probiotics - very short, researc citations 4. Enzymes and Dietary Peptides - commentary on enzymes by Jon Pangborn (see below) 5. Enzymes and Probiotics Together - short, commentary saying that enzymes and probiotics can be taken together and that the literature doesn't support the idea of probiotics and enzymes having a possible interation. This is different than Dr. Kartzinel's observation and some of the parents who feel the results were better when probiotics and enzymes are given separately. [my opinion: it may depend on the particular products involved. Kirkman may feel there is no problem with taking their enzymes and their probiotics together. I think just going with what gives you the best results depending on what you are using is best.] The article on enzymes is longer and I would appreciate anyone else reading it and posting their opinion. It is 4 pages long. Jon Pangborn was one of the first people to have the vision of a possible enzyme product to break down the potential opiate peptides. There is some background research establishing this fact. Then there are some reasons one may see adverse reactions when starting enzymes. One is further withdrawal, another is die-off of yeast/bacteria overgrowth, and a third is increased tryptophan from an increase in protein breakdown [my thoughts: I have never heard of the trytophan issue with AS and don't know anything about it...yet! lol]. Then comes the interesting part. Jon writes that these digestive enzymes (referring to Kirkman products) are NOT a substitute for the an elimination diet. That progressive removal of such foods from the diet followed by introduction of one of these enzyme formulations can lessen the intensity of withdrawal. That not all autistics have a casein or gluten exorphin problem and a trial avoidance of 30-60 days may be needed. And then that food allergy tests for casein or gluten, either IgE or IgG do NOT apply to exorphin chemistry. So the tests are not definitive as to whether you have a casein/gluten problem. [my opinion: I think that it is evident that a bunch of people are replacing the GFCF diet, or going off diet, or having infractions every half hour, or however you want to diplomatically say it, without problem. In fact, a lot of people are doing much better off diet, although this does not mean everyone is. Whether enzymes would hold up over time was not known in the beginning, but is now. So I am interested in why someone thinks that certain enzymes cannot replace (or insert another more PC term) the diet at this point in time. Why not? Maybe there is disagreement some of the terminology. Or it only applies to Kirkman enzymes and not to other brands. Complete hasn't been out as long, so it is a legitimate concern as to whether you can stay on it instead of the diet for months (my guess is it will be even if you need a slightly higher dose, based on how it worked for us, but this is just my opinion). These comments may be based on information regarding these particular enzymes I don't know about.] Then there are six Q & A questions. Two of these again repeating that digestive enzymes (at least the Kirkman ones) are not to be used off diet, and it is not reasonable to think they are effective enough to break up all the peptides. So, again, I am thinking, " Why is it not reasonable? " and would appreciate other opinions on this. Maybe there is a glaring point I am overlooking. I am basing my opinion on the fact that lots of people are doing so much better when they add enzymes even though they had been on an elimination diet for some time. Also, other people, including us, are doing much better on enzymes with regular food than eliminating foods. However, these examples are based on Peptizyde, so maybe brand plays into this. One question also says that it is important to go with your child's response and not lab tests and these are not a reliable measure of what you should do. So if we are to base our opinions on the child's response and the child is doing far better on enzymes+gluten/casein food (no elimination diet), that also points to the enzymes being a very effective or better replacement. I think it is very acceptable to say that a person MAY be able to use just certain enzymes and not need to do a certain elimination diet. . Quote Link to comment Share on other sites More sharing options...
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