Re: Re: Gentamicin question/please help.

[Guest guest]

It is my understanding that the aminoglycoside antibiotics *only* affect *hearing*

in the *very specific MtDNA deletion A1555G*.

I am not aware of any articles written, which associate aminoglycosides

with mitochondria in muscle tissue.

My comment about checking with the doctor regarding topical application was

attached to my wondering *if* aminoglycosides could enter the bloodstream

through topical application, sufficient for the aminoglycoside to do its

ototoxic damage to the very specific group of Mitochondrial patients.

Jean Shepherd

sol8air wrote:

Hi,

I'm new here. I am a registered nurse and have a child with mito.

cytopathy. As a nurse I'd say ophthalmic gent isn't absorbed

systemically and would be OK EXCEPT having a kid with this disorder

AND eye muscle problems I'd say ask your mito specialist (you've

probably learned already your GP doesn't know squat about mito). Only

the specialist knows if the eye drops are absorbed into and affect

they mitochondria in the eye muscles. Since this is a commonly

prescribed eye drop, I'm interested to hear his/her answer.

Please contact mito-owner with any problems or questions.