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Re: HISS Panel

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A HISS panel includes all of the immune globulins (IgM, IgA, IgE and IgG) as well as all of the subclasses of IgG and finally the levels of antibodies to things like the DTP and pneumococcus. Typically if someone shows low antibody titers on the HISS panel the MD has the child/adult re-vaccinated and then redraws the levels in a month or so to see if this time the person made antibodies. Depending on the results of IgG levels (both the total and the subclasses) IIVIG infusions may be recommended. If the child has low levels but is not chronically sick it would be acceptable to take a wait and see approach. IVIG is a blood product and it has its own risks so it will not be /or at least should not be given unless certain criteria are met. My boys have no antibody titers, and low IgG levels in all subclasses...they get infusions of IVIG every 3-4 weeks. We also tested their B cell number and function which was profoundly abnormal and that helped us to make the decision about IVIG infusions. Anne

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> A HISS panel includes all of the immune globulins (IgM, IgA, IgE and IgG)

as well as all of the subclasses of IgG and finally the levels of antibodies to

things like the DTP and pneumococcus.

Thanks, I guess it would help if I had my ears cleaned out. I should have

asked what the panel consisted of but it was at the end of a very long day. We

are going to give pneumovax and then recheck her.

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