Andy--Sulfite Question, Thiols, Gene 2D6

[Guest guest]

Andy, I was reading the post below, and I began to realize that I too am no

chemist and that I have ended up in the emergency room at least 4 times due

to consuming sodium bi-sulfites. I get very sick, with vomiting and diarrhea

that can last for three days. I need IV's and get mag deficient. However,

funny thing is that I can eat all the broccoli and other cruciferous veg's I

want, take MSM, and well you get the picture.

I cannot drink alcohol (vomiting) and I am sure that the sulfite issue is not

the only problem. I must have either none or low alcohol dehydrogenase,

although I have not the foggiest where to get that test. I got drunk putting

a liquor into a cake a few years ago not from drinking, but from smelling

alcohol. I could never drink. After I developed MCS, everything toxic bothers

me if I smell it or eat it. I smelled mercaptan leaking in our side yard that

the gas company's equipment did not detect. A skunk passing through our yard

has made me very ill. What in heaven's name is wrong with me?

Two questions: why can I eat high sulfur foods and not tolerate sodium

bi-sulfites?

Will I possibly have the above nasty experience when I try the DMSA?

Third question: is it possible that I took the ten DMPS IV's because they

were IV and did not hit my stomach or nose?

Fourth question: Pesticides make me very sick. I get cholinesterase

inhibition easily upon exposure. Is this a thiol thing? How can I link

thiols, sodium bi-sulfite, alcohol, mercaptan, codeine and pesticides and say

something about my intolerances that fits into some neat pattern? not

possible?

It would do me no good to tell my doctor any of this because she prescribed a

fibromyalgia drug related to gene 2D6 metabolized substances like " codeine "

(also causes me same problems and is listed on my chart " allergic to " ) and

really does not " get it " if you know what I mean. I researched the gene 2D6

issue myself at the Genelex website and saw all the drugs that make me sick,

and put me in the hospital, listed neatly under 2D6. So I figure either I

have a defect in 2D6 or I have some other general issue such as a problem

with the PPAR gene, 22q11.2. Can you venture a guess as to how this all fits

with the possiblility that DMSA might or might not make me real sick? Thanks,

Jannarone

PS I know what dot doses are.... I would take a tiny bit of the DMSA in any

event.

In http://groups.yahoo.com/group/Autism-Mercury/post?protectID=10007511400909\

9192217005163148062077039158044067209130152 " >Autism-Mercury@y..., http://groups.yahoo.com/group/Autism-Mercury/post?protectID=04514311821216\

0071015038190036129 " >jw4994@e... wrote:

> OK, I need a chemist! (Is there one on this list? lol) DH just

> asked me if there's any mercury in DMSA. He's wondering because the

> chemical name of DMSA is Meso-2,3-dimercapto succinic acid.

Mercapto

> does refer to mercury, yes?

Mercapto does NOT refer to mercury. it refers to thiols, a sulfur

with a hydrogen stuck on it that is attached to the molecule. Thiols

are the sulfur equivalent of alcohols. Ethyl alcohol is in whisky,

ethyl thiol is in natural gas as the odorant. It is more commonly

called ethyl mercaptan. Thiols smell REALLY BAD. Essence of skunk is

butyl mercaptan. Mercaptan as in Mercapto. Thus, dimercapto means

there are 2 -SH groups in DMSA, and also lets you know to expect it

not to smell very good.

Andy

>