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Re: really frustrated  ME TAYLOROKC

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> was just letting us know that he is having problems with the site,

> that is all ... as for your sugars being " high " somedays that just happens,

> you could have stress or illness any thing really could cause your body to

> react differently..

>

>

Oh and its the same today, im going to the doctor this week about my insulin,

I dont think the type agrees with me, Im getting WAAYyyy to many peaks and

drops with it, Im on novolog 70/30

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>

> In a message dated 7/31/04 4:17:45 AM, carmen33@i... writes:

> Oh and its the same today, im going to the doctor this week about

my insulin,

> I dont think the type agrees with me, Im getting WAAYyyy to many

peaks and

> drops with it, Im on novolog 70/30

GREETINGS --

It is unclear how long you have been using Novolog 70/30, but it may

be time to revaluate or ask for a change. As an example, I am an

insulin-dependent Type 2 (10+ years)who started out on pre-mixed

insulin (Humulin 70/30) and was never able to get good control with

it. As a diabetic using insulin it needs to satisfy two sets of

needs; bolus and basal. Your bolus needs are related to the glucose

produced by the food that you consume and your basal needs are

related to the insulin needed for basic body functions (especially

between meals and overnight sleep). Each of those needs will vary

from person to person and from day to day based on activities and

diet so the premixed insulins are very inefficient for this reason --

which often translates into low blood sugars when you try to keep

your highs as low as possible.

Novolog 70/30 is a pre-mixed combination of an intermediate (NPH)(70%

of each dose) and very rapid acting Novolog (30% 0f each dose)

insulins. The Novolog portion of your insulin is very rapid acting;

The rapid acting portion of the dosage begins acting 15-20 minutes

after injecting, peaks in 40-50 minutes, and ends its effect 3-4

hours after the injection. The NPH (equivalent) portion of your

insulin is a mid-range activity period; having an effect in 2-4

hours, peaking in 6-10 hours, and clearing your system after about 12

hours.

The Novolog portion of your insulin is a very rapid acting insulin

that is quite efficient in satisfying your bolus needs -- when a

dosage is injected based on the food you will be eating. In the case

of the mixture you are using, however, the the Novolog portion is

covering your breakfast, but the less efficient NPH portion is

covering your lunch, and then the Novolog portion of your second shot

is covering your supper. You end up probably having to snack over the

course of the day to keep your blood sugars from dropping too low.

The NPH-equivalent portion of your insulin has a peak which it needs

to cover your bolus needs during lunch, but that peak is not needed

for your basal requirements. They tend to be pretty constant over the

course of the day and the inefficiencies associated with the NPH-

equivalent portion could also lead to lows.

In my case, for example I use Humalog (bolus)(very rapid acting) and

Lantus (basal)(long acting) and I have been able to normalize my

insulins (and my blood sugars) which means excellent blood sugar

control and no hypoglycemic events. After a series of trial and error

tests the proportions that seem to work best for me is 55% basal

insulin and 45% bolus insulin. The likelihood of that ratio working

for you is minimal, but the odds of the optimal ratio for you being

70%/30% is probably even worse.

Once I normalized my Lantus insulin dosage (Lantus involves one shot

per day) I was able to skip or delay meals and still have my blood

sugars within normal ranges. I also was able to calculate a dosage of

Humalog for each meal based on the food I would be eating and to make

any corrections should my pre-meal blood sugars be higher then they

should be. In my mind this represent maximum efficiency and maximum

effectiveness. By switching to two insulins (Lantus and Humalog (or

Novolog)) you can accomplish this and also break any snack habit that

is now necessary, but does not need to be.

wambo1941

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Hi I'm new, just read this post & agree with the reply

from 'wambo1941'....speaking from my own case. The Long acting Lantus

in the p.m. & Humolog 'short acting' when planing to eat. My Dr.

calls this [a sliding scale] in which he advised me on paper how to

follow

counting carbs. Each person would be different. Ask your Dr. about

it/

It took me awhile, but it is a effecient method..

Krystal

> >

> > In a message dated 7/31/04 4:17:45 AM, carmen33@i... writes:

>

> > Oh and its the same today, im going to the doctor this week about

> my insulin,

> > I dont think the type agrees with me, Im getting WAAYyyy to many

> peaks and

> > drops with it, Im on novolog 70/30

>

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