Alpha Lipoic Acid Defined

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ALPHA-LIPOIC ACID

Jane Ramberg

Synonym(s): thioctic acid, pyruvate oxidation factor

Source(s): present in all plant and animal tissues

Alpha-lipoic acid (ALA), a B-complex http://www.glycoscience.com/glycoscience/# " >vitamin, is found in

mitochondrial http://www.glycoscience.com/glycoscience/# " >

proteins that play a central role in http://www.glycoscience.com/glycoscience/# " >oxidative http://www.glycoscience.com/glycoscience/# " >metabolism. An http://www.glycoscience.com/glycoscience/# " >antioxidant,

ALA can stimulate cellular levels of http://www.glycoscience.com/glycoscience/# " >glutathione.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1773&NUMBER=1 " \

>1 Research is accumulating

supporting ALA as an effective http://www.glycoscience.com/glycoscience/# " >neuroprotective agent in

treating diseases

related to oxidative stress.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1540&NUMBER=2 " \

>2 , http://www.glycoscience.com/glycoscience/reference.wm?REFID=1830&NUMBER=3 " \

>3 Supplementation with ALA protected animals

from the symptoms associated with a vitamin http://www.glycoscience.com/glycoscience/start_frames.wm?ID=796 " >E

deficiency,http://www.glycoscience.com/glycoscience/reference.wm?REFID=1539&NUMBER=4 " \

>4 protected against

age-related declines of http://www.glycoscience.com/glycoscience/# " >hepatocyte ascorbate,http://www.glycoscience.com/glycoscience/reference.wm?REFID=1830&NUMBER=3 " \

>3 and provided effective http://www.glycoscience.com/glycoscience/# " >

antioxidant support.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1829&NUMBER=5 " \

>5 Lipoic acid-supplemented animals showed improved http://www.glycoscience.com/glycoscience/# " >

metabolic activity and lowered oxidative stress.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1831&NUMBER=6 " \

>6 In an http://www.glycoscience.com/glycoscience/# " >in http://www.glycoscience.com/glycoscience/# " >vitro study,

ALA-stimulated http://www.glycoscience.com/glycoscience/# " >glucose

uptake in skeletal muscle.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1835&NUMBER=7 " \

>7 Children with inborn

errors of http://www.glycoscience.com/glycoscience/# " >pyruvate http://www.glycoscience.com/glycoscience/# " >metabolism showed

symptomatic improvement following ALA

supplementation.http://www.glycoscience.com/glycoscience/reference.wm?REFID=1540&NUMBER=2 " \

>2 ALA is used to treat individuals with http://www.glycoscience.com/glycoscience/# " >liver disease and as

an antidote to Amanita mushroom poisoning.http://www.glycoscience.com/glycoscience/reference.wm?REFID=2005&NUMBER=8 " \

>8

Date last modified: July 06, 2000