NAC - HELP - negative reations?

November 19, 2004

HELP - Our son is 3 yrs old. GFCF 7 months, now SCD 10 weeks.

Since June, he has been on... meth b-12 shots, folinic acid, oral

glutathione, super-n-t, TMG, zinc, coenzyme Q10, calcium/magnesium,

cod liver oil, enzymes and probiotics. Our DAN doctor just adder

NAC cream. WE HAVE NOT STARTED CHELATION as we can't until his

stools straiten out.

We've been giving it to him for the past 2 weeks and he has

progressively grown stimmier and the past two days has exhibited

negative behaviours. His stools have also been growing worse (but

fully digested).

Below (after my name)... you'll find two paragraphs that I found

after googling... the paragraphs are from the ARI mercury

detoxification consensus group position paper, May 2001. WHAT! IS

THIS CURRENT? IS THIS TRUE? What have we done? Will this go away

quickly? Have we further damaged our son? We have made so many

gains... WHY ON EARTH WOULD OUR DAN DOCTOR TELL US TO DO THIS?

I'm frantic. Thank you in advance, Sally

MERCURY DETOXIFICATION CONSENSUS GROUP POSITION PAPER, MAY 2001

N-Acetyl-L-Cysteine (NAC): NAC should not be used initially or by

itself with anyone suspected of having a significant body burden of

mercury. Like alpha-lipoic acid, cysteine and cystine, NAC can bind

with mercury and carry it across cell membranes. NAC is also a good

culture medium for yeast, like its parent molecule, cysteine. Since

many autistic children also have high cysteine levels, giving them

NAC will only exacerbate this problem.

NAC is often recommended because it can rapidly increase

intracellular glutathione levels 41, 42 . For that reason, it can be

tremendously useful in treating the antioxidant deficiencies seen in

so many autistic children. NAC should be used either in conjunction

with DMSA or after mercury detoxification is well under way. In

addition, NAC should be used with extreme caution in children with

elevated cysteine levels.

November 19, 2004

Sally, NAC should only be given to children with low cysteine.

You can check your son's cysteine level through Great Smokies Diag.

lab, as a subset of their Detoxification Panel.

You can start chelation (low dose, frequent dose) even if his gut is

not healed. I am glad I did not wait.

>

> HELP - Our son is 3 yrs old. GFCF 7 months, now SCD 10 weeks.

> Since June, he has been on... meth b-12 shots, folinic acid, oral

> glutathione, super-n-t, TMG, zinc, coenzyme Q10, calcium/magnesium,

> cod liver oil, enzymes and probiotics. Our DAN doctor just adder

> NAC cream. WE HAVE NOT STARTED CHELATION as we can't until his

> stools straiten out.

>

> We've been giving it to him for the past 2 weeks and he has

> progressively grown stimmier and the past two days has exhibited

> negative behaviours. His stools have also been growing worse (but

> fully digested).

>

> Below (after my name)... you'll find two paragraphs that I found

> after googling... the paragraphs are from the ARI mercury

> detoxification consensus group position paper, May 2001. WHAT! IS

> THIS CURRENT? IS THIS TRUE? What have we done? Will this go away

> quickly? Have we further damaged our son? We have made so many

> gains... WHY ON EARTH WOULD OUR DAN DOCTOR TELL US TO DO THIS?

>

> I'm frantic. Thank you in advance, Sally

>

> MERCURY DETOXIFICATION CONSENSUS GROUP POSITION PAPER, MAY 2001

> N-Acetyl-L-Cysteine (NAC): NAC should not be used initially or by

> itself with anyone suspected of having a significant body burden of

> mercury. Like alpha-lipoic acid, cysteine and cystine, NAC can bind

> with mercury and carry it across cell membranes. NAC is also a good

> culture medium for yeast, like its parent molecule, cysteine. Since

> many autistic children also have high cysteine levels, giving them

> NAC will only exacerbate this problem.

>

> NAC is often recommended because it can rapidly increase

> intracellular glutathione levels 41, 42 . For that reason, it can

be

> tremendously useful in treating the antioxidant deficiencies seen

in

> so many autistic children. NAC should be used either in conjunction

> with DMSA or after mercury detoxification is well under way. In

> addition, NAC should be used with extreme caution in children with

> elevated cysteine levels.

November 20, 2004

In a message dated 11/19/2004 11:58:55 PM Central Standard Time,

ferdeson@... writes:

> NAC should only be given to children with low cysteine.

>

For what it's worth, my son has low cysteine, but did not tolerate NAC in the

slightest. I gather this is pretty unusual.

Debbie

November 20, 2004

Sally,

I'm not the most knowledgeable on this, but do understand that DAN doctors

use all kinds of protocols, not always protocols that make sense for every

child. Some kids really have trouble with NAC, while others do not. (I

think it has something to do with sulfation? Help me, listmates?)

Keep asking around on this list, because I know that others have had both

good and bad responses with NAC.

By the way, waiting until the stools straighten out is a lost effort,

because chelation by its very nature can lead to a change in stools. He's

probably trying to heal the gut some before he starts, because some docs

believe that's really important. Others feel the gut won't heal until the

mercury comes out. Some parents have to fight horrible yeast overgrowths

once they start chelating, because their child's gut is in such bad shape.

Others, often the older kids, have resolved some of their gut issues and