Guest guest Posted January 3, 2004 Report Share Posted January 3, 2004 Insulin-Like Growth Factor-I (IGF-I) IGF-I (originally called somatomedin C) is a growth factor structurally related to insulin. IGF-I is the primary protein involved in responses of cells to growth hormone (GH): that is, IGF-I is produced in response to GH and then induces subsequent cellular activities, particularly on bone growth. It is the activity of IGF-I in response to GH that gave rise to the term somatomedin. Subsequent studies have demonstrated, however, that IGF-I has autocrine and paracrine activities in addition to the initially observed endocrine activities on bone. The IGF-I receptor, like the insulin receptor, has intrinsic tyrosine kinase activity. Owing to their structural similarities IGF-I can bind to the insulin receptor but does so at a much lower affinity than does insulin itself. http://web.indstate.edu/thcme/mwking/growth-factors.html#intro > > > > > > > > > > > > -- > > > > > > > > Can you explain the mechanism how No-Fenol allows more tyrosine? > > > > > > > > Thanks! > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2004 Report Share Posted January 3, 2004 Dev Med Child Neurol. 2001 Sep;43(9):614-6. Related Articles, Links Low levels of insulin-like growth factor-I in cerebrospinal fluid in children with autism. Vanhala R, Turpeinen U, Riikonen R. Unit of Child Neurology, Hospital for Children and Adolescents, Helsinki, Finland. raija.vanhala@... Autism is a behaviourally defined syndrome characterized by disturbances of social interaction and communication and restrictions of behaviour patterns and imagination. The pathogenesis of autism is unknown but it is suspected that a number of genetic factors may be involved. Neurotrophic factors such as insulin-like growth factor-I (IGF-I) play a role in early brain development. The aim of this study was to determine whether IGF-I levels might be associated with the development of autism. IGF-I levels were measured in the CSF of 11 children with autism (4 females, 7 males; mean age 3.8 years, SD 1.1) using a sensitive radioimmunoassay method and compared with levels in 11 control participants (6 females, 5 males; mean age 3.8 years). Levels of IGF-I in the CSF were statistically significantly lower in the children with autism than in the control children (p=0.03). IGF-I may play a role in pathogenetic mechanisms of autism and the role of neurotrophic factors in autism and other neurodevelopmental diseases should be studied further. Publication Types: * Clinical Trial * Controlled Clinical Trial PMID: 11570630 [PubMed - indexed for MEDLINE] > > > > > > > > > > > > > > > -- > > > > > > > > > > Can you explain the mechanism how No-Fenol allows more tyrosine? > > > > > > > > > > Thanks! > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2004 Report Share Posted January 4, 2004 It is also the main reason for athletes taking growth hormone, as this results in higher levels of IGF-1. An anabolic state is the main desire of most bodybuilders and this is the domain of IGF-1. Increased cell division and increased protein synthesis, stimulation of wound healing, production of immune cells, reduction of insulin demand and increased burning of fat, these are the functions of this hormone. Also anti-catabolic (check out the cortisol article), as demonstrated in several pathological states, IGF-1 is the most anabolic of all the growth factors present in whey. http://maxmag.maxsportsinternational.com/science/issue38/38sci1.htm > > > > > > > > > > > > > > > > > > -- > > > > > > > > > > > > Can you explain the mechanism how No-Fenol allows more > tyrosine? > > > > > > > > > > > > Thanks! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2004 Report Share Posted January 4, 2004 interesting about whey being anabolic(which i had to look up, anabolic: promoting synthesis, opposite of catabolic) not quite sure scd is right in trying to eliminate wheys cause of the lactose............ how does cortisol fit into this? body building must be a perseveration. > It is also the main reason for athletes taking growth hormone, as this > results in higher levels of IGF-1. An anabolic state is the main > desire of most bodybuilders and this is the domain of IGF-1. Increased > cell division and increased protein synthesis, stimulation of wound > healing, production of immune cells, reduction of insulin demand and > increased burning of fat, these are the functions of this hormone. > Also anti-catabolic (check out the cortisol article), as demonstrated > in several pathological states, IGF-1 is the most anabolic of all the > growth factors present in whey. > > http://maxmag.maxsportsinternational.com/science/issue38/38sci1.htm > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 29, 2004 Report Share Posted February 29, 2004 Dear all, I read that Tyrosine can support both Adrenal and Thyroid. But I heard that it would cause anxiety. I am very anxious. Can I take it? Anything can substitue it? Thanks, Chan. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 2, 2006 Report Share Posted March 2, 2006 "She basically said that some people, especially native americans, are very efficient users of things like tyrosine. I happen to be 1/8 Cherokee." -- Cara Cara, tyrosine seems to be very closely connected with iodine. In addition to being the base for the thyroid hormones, T3 and T4, iodine and tyrosine seem to have other relationships. You might find the following research studies of interest; both of them are talking about the relationship between iodine and tyrosine (and histidine). A newly discovered oxidant defence system and its involvement in the development of Aurelia aurita (Scyphozoa, Cnidaria): [reactive oxygen species and elemental iodine control medusa formation.] Berking S, Czech N, Gerharz M, Herrmann K, Hoffmann U, Raifer H, Sekul G, Siefker B, Sommerei A, Vedder F, 2005. "In Aurelia aurita, applied iodine induces medusa formation (strobilation). This process also occurs when the temperature is lowered. This was found to increase oxidative stress resulting in an increased production of iodine from iodide....We argue that an oxidant defence system may exist which makes use of iodide and tyrosine....Both substances together, iodide and tyrosine, form an efficient oxidant defence system which shields the tissue against damage by reactive oxygen species. In the course of evolution (from a species at the basis of the animal kingdom like Aurelia to a highly evolved species like man) the waste product thyroxin (indicating a high metabolic rate) has developed into a hormone which controls the metabolic rate." Abstract (+ free article if you'll click to recommend that your library purchases the journal) How iodine kills viruses -- Derry Email 1105. "Dilute iodine solutions kill all single celled organisms such as bacteria, viruses, fungi, and protozoa. Not only are Lugol's solutions bactericidal at high dilutions, like 1/170,000, for standard pathogens such as Staphylococcus, but also iodine has the broadest range of action, fewest side effects, and no development of bacterial resistance....Single celled organisms blissfully reproduced themselves with structural membrane proteins having the amino acid tyrosine or histidine exposed to the surrounding medium or extra-cellular fluids. Iodine kills single celled organisms by combining with these same two amino acids. All single celled organisms showing tyrosine (tyrosyl) linkages exposed in the membrane proteins are killed by this simple chemical reaction that denatures proteins and kills the cells." I don't know where this iodine - tyrosine connection is going to lead us, but somehow it seems very significant. Zoe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2009 Report Share Posted April 18, 2009 Chuck,  I was asking for inexpensive supplemental sources of tyrosine. BTW, I do not have hives. > I would like input too. My doc recommended nature-throid, tyrosine and > iodine also. Anybody have a cheap source of tyrosine? Cheese, nuts, soy, exactly the foods to avoid if you have hives, which tyrosine aggravates. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2009 Report Share Posted August 13, 2009 one of the best things for hashimoto is low dose naltrexone.some people report improvement. > > > do you feel it is useful to take tyrosine as a help for hashimoto's?? why or why not?? thanks > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2009 Report Share Posted August 13, 2009 Zahavi, What is naltrexone? one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 14, 2009 Report Share Posted August 14, 2009 here you can read about low dose naltrexone http://www.low dose naltrexone.org/ for all auto-immune diseases, copd,parkinson cancer autism and every one that was long time under stress it is the most amazing treatment. there is also a very good group for help low dose naltrexone/ > > > > > > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 14, 2009 Report Share Posted August 14, 2009 thank you...i joined the site too....sounds very promising! From: zahavi <zahavi100@...>Subject: Re: tyrosineiodine Date: Friday, August 14, 2009, 6:03 AM here you can read about low dose naltrexonehttp://www.lowdosen altrexone. org/for all auto-immune diseases, copd,parkinson cancer autism and every one that was long time under stress it is the most amazing treatment.there is also a very good group for help http://health. groups.. com/group/ lowdosenaltrexon e/> >> > > > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 14, 2009 Report Share Posted August 14, 2009 i wish you success.i have seen amazing results with ldn.copd,AS,crohn,hepatetis. > > > > > > > > > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2009 Report Share Posted August 17, 2009 these are the results for my 11 year old..i already have 2 kids with hashi's...she is on about 6.5 mg of iodine...selenium 100 mcg, magnesium, iron 85 mg at night...methlated b complex...vitamin d3she has had past anxiety and mild adhd...her tsh was 2.9 (.360-5.8)FT3 4.3 (2.6-5.7)FT4 1.02 (0.79-1.49)ferritin 31 (10-291)i am wondering if her tsh is a bit elevated due to iodine intake...her ft3 seems to be in upper range ft4 is right in middle...what do you think...i am soooo tired of my kids needing all these tests...so far this child has not had antibody testing..i am trying to raise her ferritin and give iodine time to work on her...she has only been on it for about 3 months....any advice?? From: meredithsenter <meredithsenter>Subject: Re: Re: tyrosineiodinegroups (DOT) comDate: Thursday, August 13, 2009, 4:21 PM How so? What were the benefits to gluten free and ldn. Has anyone benefitted from tyrosineSent from my Verizon Wireless BlackBerry Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2009 Report Share Posted August 17, 2009 Here Free T4 looks like my children when they began taking Armour. IMHO it's too low. 4.6 is the beginning of the upper 1/3 of the range and she isn't there. Most feel best in the upper 1/3 of the range. Mid range isn't going to cut it. Ferritin is too low. Should be 50-60. Her TSH is too high. The only way to know if it is iodine related is to take a thyroglobulin level. It is elevated when attempting to bind to iodine. I would like to see antibodies here too. Is she gluten free? That may help ADHD issues along with removing dairy. I know she's 11 and that is hard. Sounds like she has some adrenal issues. Is her face clear or does she have acne? How are her cycles? Does she have mood swings with her cycles? You have part of the puzzle and my guess is she is hypo and could use a boost. Puberty makes you need more thyroid hormone. Steph Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 18, 2009 Report Share Posted August 18, 2009 My children take it M/W/F My son is almost 10. Steph Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 20, 2009 Report Share Posted August 20, 2009 I tried tyrosine last year after reading a book by Dr Cousens where he spoke at length about balancing amino acids. It gave me a seriously upset stomach if taken without food, and even with food, it didn't sit well. Jana dawn volz wrote: >do you feel it is useful to take tyrosine as a help for hashimoto's?? why or why not?? thanks > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 20, 2009 Report Share Posted August 20, 2009 Could it have been the particular brand you used? It's really hard to find pure products as almost "everyone" puts magnesium stearate and/or stearic acid in their supplements... All I know is that whenever possible I'm ordering powdered supplements to encapsulate myself.Raquel> > >do you feel it is useful to take tyrosine as a help for hashimoto's?? why or why not?? thanks > >> > > >> Quote Link to comment Share on other sites More sharing options...
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