Re: Tics- or PANDAS - Is my son needing specialized doctors? another EBV cite

[Guest guest]

Here's another citation, noting that " Events

considered to predispose to or cause recurrent tonsillitis (RT) include the

misuse of antibiotic therapy in acute bouts, alterations in the microflora,

structural changes in crypt epithelium and certain viral infections.

Epstein-Barr Virus (EBV) infection usually occurs in early childhood and can

persist in palatine tonsil lymphocytes to induce tonsillitis at a later date. "

(1)

Ruling out EBV seems important for your son. Amalgam-fogged memory tells me

that this can be done w/o surgery. If surgery occurs, you can stridently demand

that a tissue sample be saved and evaluated for EBV. 'Tis a nasty virus if

persistently festering.

1: Int J Pediatr Otorhinolaryngol. 2001 Apr 6;58(1):9-15.

Detection of Epstein-Barr virus in tonsillar tissue of children and the

relationship with recurrent tonsillitis.

Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE Jr,

Vassallo J.

Pediatric Otorhinolaryngology Service, State University of Campinas, Campinas,

Sao o, Brazil. luiza_endo@...

Recurrent tonsillitis has been the subject of much investigation. Events

considered to predispose to or cause recurrent tonsillitis (RT) include the

misuse of antibiotic therapy in acute bouts, alterations in the microflora,

structural changes in crypt epithelium and certain viral infections.

Epstein-Barr Virus (EBV) infection usually occurs in early childhood and can

persist in palatine tonsil lymphocytes to induce tonsillitis at a later date. We

have examined the presence of EBV in palatine tonsils in order to assess the

relationship between this virus and recurrent acute tonsillitis. Tonsils were

obtained from 85 patients, 2--14 years old (mean 5.6 years old) who underwent

tonsils and adenoid (T & A) removal because of recurrent tonsillitis (RT) or T & A

hypertrophy (TH). Tissues specimens were processed for non-isotopic in situ

hybridization (ISH) using EBER 1/2 oligonucleotides (EBER RNA). The indications

for surgery were RT in 42 patients and TH in 43 patients. In 25 out of 85 cases

(29.4%) a positive EBER RNA reaction (15 RT and 33 TH) was found. The

chi(2)-test showed no statistically significant difference in frequency of

positive results between RT and TH group. We conclude that tonsils of children

can be colonized by EBV and that the virus may be implicated in RT and TH.

Publication Types:

Clinical Trial

PMID: 11249975 [PubMed - indexed for MEDLINE]

Asmus wrote:

>Hi all,

>

>Hope everyone is well. We have been really struggling over here, so I

>havent been online much... quick update.

>

>le (7) - My previous " NT " daughter, just diagnosed bipolar and

>PDD. Armor thyroid helping food cravings with hypoglycemia somewhat~ but

>frustration and explosive behavior a major problem.

>Diet-enzymes-suppliments show no noticable effects to date. I am having

>here krytopyrroles tested to see if she has pyrroloria(sp).

>

>Devon (5) - HFA - I cant believe this- but he now has tics. For a while

>I thought it was a stim. I realise now- no way. He cant control them.

>Whats wierd is they are primarily oral (although I think his eyeblinking

>may be one as well)- and they evolve. For instance- the first one was a

>quick/deep inhale while holding his mouth a certain way. Then it seemed

>to switch to holding his mouth open for a very long time, and then

>exhaling and saying " hey " . He would also grunt occasionally. Now he is

>growling really loud- almost like clearing your throat. We asked him if

>his throat hurt, and he did say no. Also- if you copy his tic, he will

>get upset. If he is walking or running, he will suddenly stop, and have

>a tic. Depending on the day, they rangle from every 5 seconds to once an

>hour. They are getting bad! I even did the vitamin A protocol just to

>see if the eyeblinking was related to that. I thought I saw some

>improvement- but I guess thats a whole other post.

>

>Some of you may remember me talking about his chronic tonsilitis- and

>how they wanted to take is tonsils out- well that never happened and the

>tonsilits hasn't gone away. This issue did arise a few months after back

>to back strep infections. We have tried different things- nothing is

>helping yet. I am getting close to trying homeopathy.

>

>I think my doctor would be willing to order whatever tests, but I dont

>know if he can interpret them. Anyone out there have this happen? Have

>any ideas what tests are appropriate to determine PANDAS and what

>treatment works- if any?

>

>Thanks much,

>

>

>

>

>

>

>

[Guest guest]

Thank you for your reply's.

Sounds reasonable. I wish I had a doctor that was better versed in

figuring out what tests to run... So he would need to be tested for

mono? Way back- they were considering that- but never did. So, folks

that get mono- take valtrex? You wouldn't have any ideas concerning the

protocol would you?

Thanks,

Re: [ ] Tics- or PANDAS - Is my son needing

specialized doctors? another EBV cite

Here's another citation, noting that " Events

considered to predispose to or cause recurrent tonsillitis (RT) include

the misuse of antibiotic therapy in acute bouts, alterations in the

microflora, structural changes in crypt epithelium and certain viral

infections. Epstein-Barr Virus (EBV) infection usually occurs in early

childhood and can persist in palatine tonsil lymphocytes to induce

tonsillitis at a later date. " (1)

Ruling out EBV seems important for your son. Amalgam-fogged memory tells

me

that this can be done w/o surgery. If surgery occurs, you can stridently

demand that a tissue sample be saved and evaluated for EBV. 'Tis a nasty

virus if

persistently festering.

1: Int J Pediatr Otorhinolaryngol. 2001 Apr 6;58(1):9-15.

Detection of Epstein-Barr virus in tonsillar tissue of children and the

relationship with recurrent tonsillitis.

Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE

Jr, Vassallo J.

Pediatric Otorhinolaryngology Service, State University of Campinas,

Campinas, Sao o, Brazil. luiza_endo@...

Recurrent tonsillitis has been the subject of much investigation. Events

considered to predispose to or cause recurrent tonsillitis (RT) include

the misuse of antibiotic therapy in acute bouts, alterations in the

microflora, structural changes in crypt epithelium and certain viral

infections. Epstein-Barr Virus (EBV) infection usually occurs in early

childhood and can persist in palatine tonsil lymphocytes to induce

tonsillitis at a later date. We have examined the presence of EBV in

palatine tonsils in order to assess the relationship between this virus

and recurrent acute tonsillitis. Tonsils were obtained from 85 patients,

2--14 years old (mean 5.6 years old) who underwent tonsils and adenoid

(T & A) removal because of recurrent tonsillitis (RT) or T & A hypertrophy

(TH). Tissues specimens were processed for non-isotopic in situ

hybridization (ISH) using EBER 1/2 oligonucleotides (EBER RNA). The

indications for surgery were RT in 42 patients and TH in 43 patients. In

25 out of 85 cases

(29.4%) a positive EBER RNA reaction (15 RT and 33 TH) was found. The

chi(2)-test showed no statistically significant difference in frequency

of positive results between RT and TH group. We conclude that tonsils of

children can be colonized by EBV and that the virus may be implicated in

RT and TH.

Publication Types:

Clinical Trial

PMID: 11249975 [PubMed - indexed for MEDLINE]

Asmus wrote:

>Hi all,

>

>Hope everyone is well. We have been really struggling over here, so I

>havent been online much... quick update.

>

>le (7) - My previous " NT " daughter, just diagnosed bipolar and

>PDD. Armor thyroid helping food cravings with hypoglycemia somewhat~

>but frustration and explosive behavior a major problem.

>Diet-enzymes-suppliments show no noticable effects to date. I am having

>here krytopyrroles tested to see if she has pyrroloria(sp).

>

>Devon (5) - HFA - I cant believe this- but he now has tics. For a while

>I thought it was a stim. I realise now- no way. He cant control them.

>Whats wierd is they are primarily oral (although I think his

>eyeblinking may be one as well)- and they evolve. For instance- the

>first one was a quick/deep inhale while holding his mouth a certain

>way. Then it seemed to switch to holding his mouth open for a very long

>time, and then exhaling and saying " hey " . He would also grunt

>occasionally. Now he is growling really loud- almost like clearing your

>throat. We asked him if his throat hurt, and he did say no. Also- if

>you copy his tic, he will get upset. If he is walking or running, he

>will suddenly stop, and have a tic. Depending on the day, they rangle

>from every 5 seconds to once an hour. They are getting bad! I even did

>the vitamin A protocol just to see if the eyeblinking was related to

>that. I thought I saw some

>improvement- but I guess thats a whole other post.

>

>Some of you may remember me talking about his chronic tonsilitis- and

>how they wanted to take is tonsils out- well that never happened and

>the tonsilits hasn't gone away. This issue did arise a few months after

>back to back strep infections. We have tried different things- nothing

>is helping yet. I am getting close to trying homeopathy.

>

>I think my doctor would be willing to order whatever tests, but I dont

>know if he can interpret them. Anyone out there have this happen? Have

>any ideas what tests are appropriate to determine PANDAS and what

>treatment works- if any?

>

>Thanks much,

>

>

>

>

>

>

>

=======================================================

[Guest guest]

One abstract read this morning said that although most strains of EBV

are inhibited by Valtrex, folks with EBV-related mono don't benefit from

Valtrex (which, I surmise w/o the study in hand) is due to the

individual's excessive immune suppression which potentiates the

mono-potential of EBV. Of course, a statistical finding doesn't rule

out that at least some folks in the study might have benefited, and if

your son isn't amidst mono, then Valtrex might be a tad more effective.

Evaluating nutritional status re: " essential elements " and amino acids

might lead to a route whereby immunity could be boosted nutritionally.

In that context, Valtrex might be useful as a temporary crutch to help

immuno-suppress EBV.

non-MD researcher

Asmus wrote:

>Thank you for your reply's.

>

>Sounds reasonable. I wish I had a doctor that was better versed in

>figuring out what tests to run... So he would need to be tested for

>mono? Way back- they were considering that- but never did. So, folks

>that get mono- take valtrex? You wouldn't have any ideas concerning the

>protocol would you?

>

>Thanks,

>

>

>

> Re: [ ] Tics- or PANDAS - Is my son needing

>specialized doctors? another EBV cite

>

>

>Here's another citation, noting that " Events

>considered to predispose to or cause recurrent tonsillitis (RT) include

>the misuse of antibiotic therapy in acute bouts, alterations in the

>microflora, structural changes in crypt epithelium and certain viral

>infections. Epstein-Barr Virus (EBV) infection usually occurs in early

>childhood and can persist in palatine tonsil lymphocytes to induce

>tonsillitis at a later date. " (1)

>

>Ruling out EBV seems important for your son. Amalgam-fogged memory tells

>me

>that this can be done w/o surgery. If surgery occurs, you can stridently

>demand that a tissue sample be saved and evaluated for EBV. 'Tis a nasty

>virus if

>persistently festering.

>

>

>

>1: Int J Pediatr Otorhinolaryngol. 2001 Apr 6;58(1):9-15.

>

>Detection of Epstein-Barr virus in tonsillar tissue of children and the

>relationship with recurrent tonsillitis.

>

>Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE

>Jr, Vassallo J.

>

>Pediatric Otorhinolaryngology Service, State University of Campinas,

>Campinas, Sao o, Brazil. luiza_endo@...

>

>Recurrent tonsillitis has been the subject of much investigation. Events

>considered to predispose to or cause recurrent tonsillitis (RT) include

>the misuse of antibiotic therapy in acute bouts, alterations in the

>microflora, structural changes in crypt epithelium and certain viral

>infections. Epstein-Barr Virus (EBV) infection usually occurs in early

>childhood and can persist in palatine tonsil lymphocytes to induce

>tonsillitis at a later date. We have examined the presence of EBV in

>palatine tonsils in order to assess the relationship between this virus

>and recurrent acute tonsillitis. Tonsils were obtained from 85 patients,

>2--14 years old (mean 5.6 years old) who underwent tonsils and adenoid

>(T & A) removal because of recurrent tonsillitis (RT) or T & A hypertrophy

>(TH). Tissues specimens were processed for non-isotopic in situ

>hybridization (ISH) using EBER 1/2 oligonucleotides (EBER RNA). The

>indications for surgery were RT in 42 patients and TH in 43 patients. In

>25 out of 85 cases

>(29.4%) a positive EBER RNA reaction (15 RT and 33 TH) was found. The

>chi(2)-test showed no statistically significant difference in frequency

>of positive results between RT and TH group. We conclude that tonsils of

>children can be colonized by EBV and that the virus may be implicated in

>RT and TH.

>

>Publication Types:

> Clinical Trial

>

>PMID: 11249975 [PubMed - indexed for MEDLINE]

>

>

>

> Asmus wrote:

>

>

>

>>Hi all,

>>

>>Hope everyone is well. We have been really struggling over here, so I

>>havent been online much... quick update.

>>

>>le (7) - My previous " NT " daughter, just diagnosed bipolar and

>>PDD. Armor thyroid helping food cravings with hypoglycemia somewhat~

>>but frustration and explosive behavior a major problem.

>>Diet-enzymes-suppliments show no noticable effects to date. I am having

>>

>>

>

>

>

>>here krytopyrroles tested to see if she has pyrroloria(sp).

>>

>>Devon (5) - HFA - I cant believe this- but he now has tics. For a while

>>

>>

>

>

>

>>I thought it was a stim. I realise now- no way. He cant control them.

>>Whats wierd is they are primarily oral (although I think his

>>eyeblinking may be one as well)- and they evolve. For instance- the

>>first one was a quick/deep inhale while holding his mouth a certain

>>way. Then it seemed to switch to holding his mouth open for a very long

>>

>>

>

>

>

>>time, and then exhaling and saying " hey " . He would also grunt

>>occasionally. Now he is growling really loud- almost like clearing your

>>

>>

>

>

>

>>throat. We asked him if his throat hurt, and he did say no. Also- if

>>you copy his tic, he will get upset. If he is walking or running, he

>>will suddenly stop, and have a tic. Depending on the day, they rangle

>>

>>

>>from every 5 seconds to once an hour. They are getting bad! I even did

>

>

>>the vitamin A protocol just to see if the eyeblinking was related to

>>that. I thought I saw some

>>improvement- but I guess thats a whole other post.

>>

>>Some of you may remember me talking about his chronic tonsilitis- and

>>how they wanted to take is tonsils out- well that never happened and

>>the tonsilits hasn't gone away. This issue did arise a few months after

>>

>>

>

>

>

>>back to back strep infections. We have tried different things- nothing

>>is helping yet. I am getting close to trying homeopathy.

>>

>>I think my doctor would be willing to order whatever tests, but I dont

>>know if he can interpret them. Anyone out there have this happen? Have

>>any ideas what tests are appropriate to determine PANDAS and what

>>treatment works- if any?

>>

>>Thanks much,

>>

>>

>>

>>

>>

>>

>>

>>

>>

>

>

>

>

>

>=======================================================

>