Guest guest Posted March 27, 2004 Report Share Posted March 27, 2004 Here is some latest research on glucosamine sulfate. I'm still in a holding pattern with my right hip until I can arrange to go to Dr. De Smet. Not long ago I ran out of glucosamine and a couple of weeks later, it became very painful. I immediately replenished my supply and along with being back in the gym doing the bike and leg presses, curls & extensions, the pain is surprisingly well-maintained. Rainer " Glucosamine may do more than simply reduce osteoarthritis pain. New findings, published in the March/April 2004 issue of the Journal of Menopause, indicate that glucosamine may actually reduce or reverse disease progression in some people. These findings originate from two studies involving 414 mostly postmenopausal women with knee osteoarthritis. Half received 1,500 mg of glucosamine sulfate daily while the other half received a placebo. After three years, those taking glucosamine had no further loss of cartilage whereas the placebo group continued to experience cartilage destruction. Pain reduction and joint function also improved significantly in the group receiving glucosamine sulfate. Previous studies published in Archives of Internal Medicine and The Lancet, also found similar levels of improvement using the same daily dosage of glucosamine that was used in this study. Although there is still no good evidence that glucosamine should be taken as a preventative measure in younger adults, the results of this study confirm that if you already have osteoarthritis, taking glucosamine may be beneficial. This information is brought to you by USANA Science Information Services. Bruyere O, Pavelka K, Rovati LC, Deroisy R, Olejarova M, Gatterova J, Giacovelli G, Reginster JY. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies. Menopause. 2004;11 (2):138-143. Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati LC. Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double- blind study. Arch Intern Med. 2002 Oct 14;162(18):2113-23. Reginster JY, Deroisy R, Rovati LC, Lee RL, Lejeune E, Bruyere O, Giacovelli G, Henrotin Y, Dacre JE, Gossett C. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet. 2001 Jan 27;357(9252):251- 6 " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2004 Report Share Posted March 28, 2004 Thanks Rainer, I'm off to take mine now! zoe > Here is some latest research on glucosamine sulfate. I'm still in a > holding pattern with my right hip until I can arrange to go to Dr. De > Smet. Not long ago I ran out of glucosamine and a couple of weeks > later, it became very painful. I immediately replenished my supply > and along with being back in the gym doing the bike and leg presses, > curls & extensions, the pain is surprisingly well-maintained. > > Rainer > > " Glucosamine may do more than simply reduce osteoarthritis pain. New > findings, published in the March/April 2004 issue of the Journal of > Menopause, indicate that glucosamine may actually reduce or reverse > disease progression in some people. These findings originate from > two studies involving 414 mostly postmenopausal women with knee > osteoarthritis. Half received 1,500 mg of glucosamine sulfate daily > while the other half received a placebo. > > After three years, those taking glucosamine had no further loss of > cartilage whereas the placebo group continued to experience cartilage > destruction. Pain reduction and joint function also improved > significantly in the group receiving glucosamine sulfate. Previous > studies published in Archives of Internal Medicine and The Lancet, > also found similar levels of improvement using the same daily dosage > of glucosamine that was used in this study. > > Although there is still no good evidence that glucosamine should be > taken as a preventative measure in younger adults, the results of > this study confirm that if you already have osteoarthritis, taking > glucosamine may be beneficial. > > This information is brought to you by USANA Science Information > Services. > > Bruyere O, Pavelka K, Rovati LC, Deroisy R, Olejarova M, Gatterova J, > Giacovelli G, Reginster JY. Glucosamine sulfate reduces > osteoarthritis progression in postmenopausal women with knee > osteoarthritis: evidence from two 3-year studies. Menopause. 2004;11 > (2):138-143. > > Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati > LC. Glucosamine sulfate use and delay of progression of knee > osteoarthritis: a 3-year, randomized, placebo-controlled, double- > blind study. Arch Intern Med. 2002 Oct 14;162(18):2113-23. > > Reginster JY, Deroisy R, Rovati LC, Lee RL, Lejeune E, Bruyere O, > Giacovelli G, Henrotin Y, Dacre JE, Gossett C. Long-term effects of > glucosamine sulphate on osteoarthritis progression: a randomised, > placebo-controlled clinical trial. Lancet. 2001 Jan 27;357 (9252):251- > 6 " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2004 Report Share Posted March 28, 2004 when I was first diagnosed with OA in '97 a bought a 10 kilo box of very high quality straight from the manufacturer and have been taking it to this day. I was bone to bone on one side and it really did help but did not reverse it like I had hoped. and eventually the the other side deteriorated so I got a bilat from DeSmet in '03. I will say the cartiledge in my back is so thick it took the anethesiologist 15 minutes to put the catheter in during preop(very painful!) and said " i will never have a problem with my back " xrays show same with shoulders, and knees are perfect. I'm convinced its because of glucosamine and mineral supps but my pelvis was too twisted and too much torque for it to completely reverse the damaged hip joints but I tried for 6 years. good info, thanks Jeff > Here is some latest research on glucosamine sulfate. I'm still in a > holding pattern with my right hip until I can arrange to go to Dr. De > Smet. Not long ago I ran out of glucosamine and a couple of weeks > later, it became very painful. I immediately replenished my supply > and along with being back in the gym doing the bike and leg presses, > curls & extensions, the pain is surprisingly well-maintained. > > Rainer > > " Glucosamine may do more than simply reduce osteoarthritis pain. New > findings, published in the March/April 2004 issue of the Journal of > Menopause, indicate that glucosamine may actually reduce or reverse > disease progression in some people. These findings originate from > two studies involving 414 mostly postmenopausal women with knee > osteoarthritis. Half received 1,500 mg of glucosamine sulfate daily > while the other half received a placebo. > > After three years, those taking glucosamine had no further loss of > cartilage whereas the placebo group continued to experience cartilage > destruction. Pain reduction and joint function also improved > significantly in the group receiving glucosamine sulfate. Previous > studies published in Archives of Internal Medicine and The Lancet, > also found similar levels of improvement using the same daily dosage > of glucosamine that was used in this study. > > Although there is still no good evidence that glucosamine should be > taken as a preventative measure in younger adults, the results of > this study confirm that if you already have osteoarthritis, taking > glucosamine may be beneficial. > > This information is brought to you by USANA Science Information > Services. > > Bruyere O, Pavelka K, Rovati LC, Deroisy R, Olejarova M, Gatterova J, > Giacovelli G, Reginster JY. Glucosamine sulfate reduces > osteoarthritis progression in postmenopausal women with knee > osteoarthritis: evidence from two 3-year studies. Menopause. 2004;11 > (2):138-143. > > Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati > LC. Glucosamine sulfate use and delay of progression of knee > osteoarthritis: a 3-year, randomized, placebo-controlled, double- > blind study. Arch Intern Med. 2002 Oct 14;162(18):2113-23. > > Reginster JY, Deroisy R, Rovati LC, Lee RL, Lejeune E, Bruyere O, > Giacovelli G, Henrotin Y, Dacre JE, Gossett C. Long-term effects of > glucosamine sulphate on osteoarthritis progression: a randomised, > placebo-controlled clinical trial. Lancet. 2001 Jan 27;357 (9252):251- > 6 " Quote Link to comment Share on other sites More sharing options...
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