Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 lots of things determind this, just like everyone one of us is differant, so are our doctors. and so is our cancer. size, how aggressive, patients age, and so on and so on. i think more doctors are trying to make each patient their own, so no 2 woman are alike and neither is their treatment. hope this helps hugs & prayers from carol in michigan -- Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 – I can only give you my experience. When I had the lumpectomy, my surgeon said I would probably only need radiation. But when the pathology report came back that my margins weren’t clear we had to go ahead with a mastectomy. After THAT pathology report, he told me the margins were now clear and radiation wouldn’t help. He referred me to an oncologist with which I did a minimum course of chemo. The oncologist also checked with their radiation department and it was confirmed that radiation wouldn’t help in my case. I’m guessing it’s because they felt they got all the cancer with the second surgery and the chemo was just precautionary. Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 , Each dr and each patient is different. It all depends on what the circumstances are. Some drs give chemo first if the tumor is too big in hopes of shrinking it before surgery. I will keep your Aunts in my prayers. Hugs nne Breast Cancer Patients Soul Mates for Life http://www.geocities.com/chucky5741/breastcancerpatients.html BreastCancerStories.com http://www.breastcancerstories.com/content/view/433/161/ Angel Feather Loomer www.angelfeatherloomer.blogspot.com Check out my other ornaments at www.geocities.com/chucky5741/bcornament.html Lots of info and gifts at: www.cancerclub.com Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 , Each dr and each patient is different. It all depends on what the circumstances are. Some drs give chemo first if the tumor is too big in hopes of shrinking it before surgery. I will keep your Aunts in my prayers. Hugs nne Breast Cancer Patients Soul Mates for Life http://www.geocities.com/chucky5741/breastcancerpatients.html BreastCancerStories.com http://www.breastcancerstories.com/content/view/433/161/ Angel Feather Loomer www.angelfeatherloomer.blogspot.com Check out my other ornaments at www.geocities.com/chucky5741/bcornament.html Lots of info and gifts at: www.cancerclub.com Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 thank you Cath Margarita was also reffered to a radiologist who also said she didnt need the radiation...... thank God for that and yes we are alslo GUESSING they feel they got it all..... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 thank you Cath Margarita was also reffered to a radiologist who also said she didnt need the radiation...... thank God for that and yes we are alslo GUESSING they feel they got it all..... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 Thank you ne --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 Thank you ne --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 Thank you Carol, it does help. this is sort of the answer I gave them specially since they are both going to the same surgeon and same oncologist, just like I am triying to convince them that just because they are twins it dont mean if one med is not good for one , it wont be for the other,,,,,, they are not identical twins but we do think is " weird " that one had the cancer on the left breast and the other on the rigth.... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 I am sorry Rhonda this part of your post has me upset with the wording you have chosen. HOW can you say a YOUNGER person needs a better shot at a cure or longevity, and older person doesn't need to buy as much time. I am so very glad that my ONC doesn't feel the same. In a message dated 9/24/2006 8:21:43 AM Central Daylight Time, rhondakarl7@... writes: A younger person can usually handle a more aggressive treatment, and they need a better shot at cure or longevity. Whereas, you wouldn't necessarily put an older person's body through that severe of treatment. They don't need to buy as much time, Vicki K. Dallas/Fort Worth, Texas _Our Fur Kid's_ (http://www.picturetrail.com/yorkies4times) Biopsy Dx'd 3-23-05 w/ 3 cm tumor MRM 4-5-05 w/ 2 tumor's 5 cm, and 6 cm (right side) 5+/16 nodes Stage III A ER/PR-, Her2/neu ++ Begin Chemo 5-2-05 4XAC Dose Dense, 4X Abraxane Dose Dense (ended August 05) 28 Rad's ended October 13, 2005 Started Herceptin Weekly August 2005 for one year, will be done this August 2006. Had a Simple mastectomy left side after Mamo showed increased micro-calcifications. Jan. 17 2006 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 I am sorry Rhonda this part of your post has me upset with the wording you have chosen. HOW can you say a YOUNGER person needs a better shot at a cure or longevity, and older person doesn't need to buy as much time. I am so very glad that my ONC doesn't feel the same. In a message dated 9/24/2006 8:21:43 AM Central Daylight Time, rhondakarl7@... writes: A younger person can usually handle a more aggressive treatment, and they need a better shot at cure or longevity. Whereas, you wouldn't necessarily put an older person's body through that severe of treatment. They don't need to buy as much time, Vicki K. Dallas/Fort Worth, Texas _Our Fur Kid's_ (http://www.picturetrail.com/yorkies4times) Biopsy Dx'd 3-23-05 w/ 3 cm tumor MRM 4-5-05 w/ 2 tumor's 5 cm, and 6 cm (right side) 5+/16 nodes Stage III A ER/PR-, Her2/neu ++ Begin Chemo 5-2-05 4XAC Dose Dense, 4X Abraxane Dose Dense (ended August 05) 28 Rad's ended October 13, 2005 Started Herceptin Weekly August 2005 for one year, will be done this August 2006. Had a Simple mastectomy left side after Mamo showed increased micro-calcifications. Jan. 17 2006 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , nne is right. Just like there is more than one recipe for good chocolate chip cookies, sometimes there is more than one right way to treat cancers. I know they used to say that mastectomy was the equivalent of lumpectomy with radiation for some breast cancers. It is a very individual thing. Chemo before surgery is called " neoadjuvant. " It is used to get the cancer into a form that can be removed. If you have a simple chocolate covered almond sized lump, it can be removed with surgery first. But if you have something with little octopus tentacles (to be graphic and overly dramatic), you've got to shrivel up those extensions with some chemo prior to trying to take them out with surgery. When you think of surgery, think of the vein in the drumstick of the chicken. It has that sticky quality. When that is a live structure in a person, with blood flowing through it, it is delicate to separate it from the meat/muscle. That is how it is with some surgery. The tissues are sticky and delicate to separate from each other. For some surgeries they just can't do it, they have to shrink the cancer first so it's easier to cut out. Sometimes different chemo drugs are picked based on the patients age or kidney status. A younger person can usually handle a more aggressive treatment, and they need a better shot at cure or longevity. Whereas, you wouldn't necessarily put an older person's body through that severe of treatment. They don't need to buy as much time, and/or their internal organs just can't do the work involved to recover from the assault of the treatement. Studies have been done and are still being done that show the percentages for which treatment works the best (or the same) for each stage or type of cancer. But it is the individual's choice whether to go through with all their options. Sometimes treatment decisions are made based on availability. For example, if you lived in a place where radiation was a very long ways away, you might opt not to get it. Genetics are the thing of the future. Someday these treatments will probably look like leaches or castor oil that was given for everything in the olden days looks to us now. All these options will seem archaic. We will probably be able to run the biopsy specimen through some tests and tell what treatment WILL work for that person. I hope I live long enough to see it. Rhonda & nne Svihlik wrote: , Each dr and each patient is different. It all depends on what the circumstances are. Some drs give chemo first if the tumor is too big in hopes of shrinking it before surgery. I will keep your Aunts in my prayers. Hugs nne Breast Cancer Patients Soul Mates for Life http://www.geocities.com/chucky5741/breastcancerpatients.html BreastCancerStories.com http://www.breastcancerstories.com/content/view/433/161/ Angel Feather Loomer www.angelfeatherloomer.blogspot.com Check out my other ornaments at www.geocities.com/chucky5741/bcornament.html Lots of info and gifts at: www.cancerclub.com Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , nne is right. Just like there is more than one recipe for good chocolate chip cookies, sometimes there is more than one right way to treat cancers. I know they used to say that mastectomy was the equivalent of lumpectomy with radiation for some breast cancers. It is a very individual thing. Chemo before surgery is called " neoadjuvant. " It is used to get the cancer into a form that can be removed. If you have a simple chocolate covered almond sized lump, it can be removed with surgery first. But if you have something with little octopus tentacles (to be graphic and overly dramatic), you've got to shrivel up those extensions with some chemo prior to trying to take them out with surgery. When you think of surgery, think of the vein in the drumstick of the chicken. It has that sticky quality. When that is a live structure in a person, with blood flowing through it, it is delicate to separate it from the meat/muscle. That is how it is with some surgery. The tissues are sticky and delicate to separate from each other. For some surgeries they just can't do it, they have to shrink the cancer first so it's easier to cut out. Sometimes different chemo drugs are picked based on the patients age or kidney status. A younger person can usually handle a more aggressive treatment, and they need a better shot at cure or longevity. Whereas, you wouldn't necessarily put an older person's body through that severe of treatment. They don't need to buy as much time, and/or their internal organs just can't do the work involved to recover from the assault of the treatement. Studies have been done and are still being done that show the percentages for which treatment works the best (or the same) for each stage or type of cancer. But it is the individual's choice whether to go through with all their options. Sometimes treatment decisions are made based on availability. For example, if you lived in a place where radiation was a very long ways away, you might opt not to get it. Genetics are the thing of the future. Someday these treatments will probably look like leaches or castor oil that was given for everything in the olden days looks to us now. All these options will seem archaic. We will probably be able to run the biopsy specimen through some tests and tell what treatment WILL work for that person. I hope I live long enough to see it. Rhonda & nne Svihlik wrote: , Each dr and each patient is different. It all depends on what the circumstances are. Some drs give chemo first if the tumor is too big in hopes of shrinking it before surgery. I will keep your Aunts in my prayers. Hugs nne Breast Cancer Patients Soul Mates for Life http://www.geocities.com/chucky5741/breastcancerpatients.html BreastCancerStories.com http://www.breastcancerstories.com/content/view/433/161/ Angel Feather Loomer www.angelfeatherloomer.blogspot.com Check out my other ornaments at www.geocities.com/chucky5741/bcornament.html Lots of info and gifts at: www.cancerclub.com Questions, questions questions Good Morning ladies I hope you all are doing great and if not, I hope you find the strength to cope.... I always tell my aunts half the cure is attitude..... I thank all of you for all the great info, I am learning quite a lot. I asked for Margarita's ( one of the twins ) pathology report and I was surprised it was 5 pages long ,,,, awwwwwwww all those strange words...... at the moment what I am triying to do is to make sure they ( the twins ) make informed decisions.... Gloria's ( the other twin ) cancer has recurred 3 times now. this time she went first for radiation and when she is healed from that and all drains are out ( she burned severely, and keeps on accumulating fluid ) she will be starting chemo.... as I said before, Margarita just finished chemo.... they asked me, and I dont know, what determines if a patient starts with radiation or chemo? why is it that some patients get both? I thank you for your patience with me... --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Vicki, I am sorry to offend you, my intention was not to upset anyone, only to explain. Now I hope I do not stick my whole leg in my mouth. The younger person's remission needs to last longer, they have more life left to live. At 30, you want to buy 60 years, at 60, you hope you can buy 30. We can cure cancer, only sometimes we would kill the patient to do it. The patient's go through the difficult months of treatment to " buy " months or years of life. Some of the more aggressive treatments are really REALLY hard on older people, heck, they are hard on younger people. So, sometimes they are given drugs that are less toxic to deal with. It really is barbaric to put them through that, zero quality of life during that time, and they still get a good remission from it. I think it is that same old argument with lots of other health issues: just because a treatment is available is it right, appropriate, eithical, or prudent to always give it? The horror stories would keep people that get diagnosed later away from getting any treatment, and that would not be good for their survival. I hope that does not make things worse. sorry, Rhonda JVK105@... wrote: I am sorry Rhonda this part of your post has me upset with the wording you have chosen. HOW can you say a YOUNGER person needs a better shot at a cure or longevity, and older person doesn't need to buy as much time. I am so very glad that my ONC doesn't feel the same. In a message dated 9/24/2006 8:21:43 AM Central Daylight Time, rhondakarl7@... writes: A younger person can usually handle a more aggressive treatment, and they need a better shot at cure or longevity. Whereas, you wouldn't necessarily put an older person's body through that severe of treatment. They don't need to buy as much time, Vicki K. Dallas/Fort Worth, Texas _Our Fur Kid's_ (http://www.picturetrail.com/yorkies4times) Biopsy Dx'd 3-23-05 w/ 3 cm tumor MRM 4-5-05 w/ 2 tumor's 5 cm, and 6 cm (right side) 5+/16 nodes Stage III A ER/PR-, Her2/neu ++ Begin Chemo 5-2-05 4XAC Dose Dense, 4X Abraxane Dose Dense (ended August 05) 28 Rad's ended October 13, 2005 Started Herceptin Weekly August 2005 for one year, will be done this August 2006. Had a Simple mastectomy left side after Mamo showed increased micro-calcifications. Jan. 17 2006 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 I totally understand the doubts about quality vs quantity of life, is it worth it or not, when I read about all the side effects of the drug you take for 5 years, 5 years of " dragging through life " in order to hopefully " buy " life........... On the other hand I totally disagree on a younger's person treatment vs older person..... my aunts are twins, they are 64 and the way they each are reacting to the cancer and treatment itself is totally different, Margarita goes for chemo and the " worst " she'll do is lack herself in her room as much as she can the week ot the chemo session..... and she says she can take it..... where Gloria is weaker and cries for attention at the smaller sign of pain, she believes her doctors should stop their personal life in case she needs them..... in all fairness, this is Glorias 3rd time of this cancer coming back, and Margaritas first.. --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Rhonda; Thank you so very much for your patience in explaining all this and the form that you do it, wich is not only easier for me and my aunts to understand but also easier to translate and explain in a way they understand better..... you mention biopsy, and this bring to mind another question ,,,, I've heard before that sometimes taking a biopsy can act as a " trim " to the cancer and make it spread faster is this a mith? --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Hi , I believe that is based on if there are any microscopic cancer cells remaining, they may travel to other parts of the body looking for a host to grow on. That's why even when a pathology reports clear margins, the doctors don't want to wait too long to start treatment. Ramos wrote on 9/24/2006, 12:09 PM: > Rhonda; > > > I've heard before that sometimes taking a biopsy can act as a " trim > " to the cancer and make it spread faster is this a mith? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , The biopsy is surely not helping to keep the cancer isolated (not spreading). But it really is the only way to know what is going on. It is not spreading like a wild fire in strong wind from a biopsy, but it doesn't make sense to send people in for lumpectomies every time they get a benign cyst or ductal infection either. For now it is just the nature of the beast. If the biopsy proves to be malignant, then take it out. So far as I know, it is the best science we have right now. Wouldn't it be great if we could go through the transporter on Star Trek, and just beam it out? Or do non invasive lazer surgery? Who knows, maybe we will see that someday and all this present day health care will seem like jack the ripper or something. I wouldn't worry about the biopsy spreading the cancer, as long as treatment is given in short order (surgery, radiation, chemo-whatever order or combination needed). Best wishes, Rhonda Ramos wrote: Rhonda; Thank you so very much for your patience in explaining all this and the form that you do it, wich is not only easier for me and my aunts to understand but also easier to translate and explain in a way they understand better..... you mention biopsy, and this bring to mind another question ,,,, I've heard before that sometimes taking a biopsy can act as a " trim " to the cancer and make it spread faster is this a mith? --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , The biopsy is surely not helping to keep the cancer isolated (not spreading). But it really is the only way to know what is going on. It is not spreading like a wild fire in strong wind from a biopsy, but it doesn't make sense to send people in for lumpectomies every time they get a benign cyst or ductal infection either. For now it is just the nature of the beast. If the biopsy proves to be malignant, then take it out. So far as I know, it is the best science we have right now. Wouldn't it be great if we could go through the transporter on Star Trek, and just beam it out? Or do non invasive lazer surgery? Who knows, maybe we will see that someday and all this present day health care will seem like jack the ripper or something. I wouldn't worry about the biopsy spreading the cancer, as long as treatment is given in short order (surgery, radiation, chemo-whatever order or combination needed). Best wishes, Rhonda Ramos wrote: Rhonda; Thank you so very much for your patience in explaining all this and the form that you do it, wich is not only easier for me and my aunts to understand but also easier to translate and explain in a way they understand better..... you mention biopsy, and this bring to mind another question ,,,, I've heard before that sometimes taking a biopsy can act as a " trim " to the cancer and make it spread faster is this a mith? --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , You're right, the microscopic cells of a biopsied lump can be loosed during a biopsy. I think we can get too crazy with paranoia about it though. While it is a real risk, to keep it in perspective, how many hundreds or thousands of these breast biopsies are done every week day? Right now it is the standard of care. It could be possible that they develop some kind of treatment to do right at the time of biopsy to discourage such a thing, and I can't quote you the statistics of how great the risk is expected to be right now for a biopsy causing spread. The really important thing is to work on the whole lump. Cancer cells don't " hang together " like normal cells do in tissue. So that lump having " dandruff of cowboy cancer cells " is a concern as well. It is kind of like you can't worry about one suicide (homicide) bomber that breaks loose from the group, you kind of have to get them all to be out of danger. Rhonda wrote: Hi , I believe that is based on if there are any microscopic cancer cells remaining, they may travel to other parts of the body looking for a host to grow on. That's why even when a pathology reports clear margins, the doctors don't want to wait too long to start treatment. Ramos wrote on 9/24/2006, 12:09 PM: > Rhonda; > > > I've heard before that sometimes taking a biopsy can act as a " trim > " to the cancer and make it spread faster is this a mith? > --------------------------------- Talk is cheap. Use Yahoo! Messenger to make PC-to-Phone calls. Great rates starting at 1¢/min. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 , You're right, the microscopic cells of a biopsied lump can be loosed during a biopsy. I think we can get too crazy with paranoia about it though. While it is a real risk, to keep it in perspective, how many hundreds or thousands of these breast biopsies are done every week day? Right now it is the standard of care. It could be possible that they develop some kind of treatment to do right at the time of biopsy to discourage such a thing, and I can't quote you the statistics of how great the risk is expected to be right now for a biopsy causing spread. The really important thing is to work on the whole lump. Cancer cells don't " hang together " like normal cells do in tissue. So that lump having " dandruff of cowboy cancer cells " is a concern as well. It is kind of like you can't worry about one suicide (homicide) bomber that breaks loose from the group, you kind of have to get them all to be out of danger. Rhonda wrote: Hi , I believe that is based on if there are any microscopic cancer cells remaining, they may travel to other parts of the body looking for a host to grow on. That's why even when a pathology reports clear margins, the doctors don't want to wait too long to start treatment. Ramos wrote on 9/24/2006, 12:09 PM: > Rhonda; > > > I've heard before that sometimes taking a biopsy can act as a " trim > " to the cancer and make it spread faster is this a mith? > --------------------------------- Talk is cheap. Use Yahoo! Messenger to make PC-to-Phone calls. Great rates starting at 1¢/min. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Rhonda, Once again, thank you for your info will you be so kind as to explain Herceptin? --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Rhonda, Once again, thank you for your info will you be so kind as to explain Herceptin? --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 26, 2006 Report Share Posted September 26, 2006 , Erb 1 and Erb 2 are receptors on breast cancer cells. Erb 2 = Her 2 neu. When the breast cancer is Her 2 neu positive by FISH, patient is eligible for the study drug Lapatinib that works on Erb 1 and Erb 2. This drug will be released in January. The immunohistochemisty test or IHC is the old test for Her 2 neu (Erb 2). It is not as sensitive as the FISH. Our local pathology routinely do IHC, but my doctors want them to do the FISH. The FISH has to be sent out for. Someone who is Her 2 neu 3+ by IHC will usually be Her 2 neu positive by FISH. Anything less than Her 2 neu 3+ will not be FISH positive. Herceptin is an antibody, it is technically not a chemotherapy drug. Herceptin is effective against Her 2 neu positive tumors. In the adjuvant setting, it is given for up to a year. In the metastatic setting, it is never stopped (well, never say never, but it can be given for many years). We have patients who have been on it for something like 9-11 years. I guess whenever it first came out. I have seen patients get muscle/joint aches, headaches, fatigue, and swelling with it. There is that little issue of the ejection fraction of the biggest chamber of the heart too...Can't do jumping jacks all day with a weak and boggy heart. The heart does heal though, but it takes time, and maybe not 100%, it depends. Hope that helps, Rhonda Ramos wrote: Rhonda, Once again, thank you for your info will you be so kind as to explain Herceptin? --------------------------------- Quote Link to comment Share on other sites More sharing options...
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