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Re: DM kinds

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About that inhaled insulin, Edd...No studies have been done on the

effect of it on the lungs longterm...and since diabetes is a lifetime

disease, that means many who decide to start inhaled insulin have no

idea what effect years of its use will have on the lungs.

As far as I'm concerned, I'd rather take my insulin in shot form. It

doesn't hurt anyway.

Vicki

Re: DM kinds

> Donna wrote:

>

>>Sorry. As usual my hands are ahead of my head.

>>In my question I referred to type 2 diabetes.

>>For some reason I had a notion that insulin dependent type 2 is more

>>serious case than one controlled by oral medication. I recognize the

>>necessity of diet and exercise in either case.

>>

>

> Commonly, people seem to believe that insulin is a last resort.

> I think it's because most people really don't want to take shots.

> They

> think it will hurt. It's easier to take a pill than inject. Also,

> doctors don't like being yelled at, so they tend to want to put off

> using insulin until they have too. Those are just emotional reasons,

> but it means many people want to avoid insulin (or perhaps just the

> injections) as long as they have. This includes the doctors who have

> created guidelines which tell them to use oral drugs first.

>

>

> But is that best for the patient? Probably not. There have

> been

> studies which showed that when newly diagnosed diabetics are

> immediately

> started on insulin, they stay healthier longer than other diabetics.

> But everybody's afraid of needles, so they want to start with oral

> drugs.

>

>

> So no. Generally, using insulin doesn't mean you've got a

> desperate case of diabetes. It may just mean you're smart or your

> doctor's smart.

>

>

> Think about this. Would people get upset about insulin if they

> could take it like a pill? No needles? Well, a new insulin has just

> been approved which is inhaled. No needles. I think most people

> will

> stop objecting to insulin if there are no needles.

>

>

> Edd

>

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Type 1 and Type 2 are not the same condition -- the etiology for each

are completely different and unrelated. Type 1 is an autoimmune

disease, where the body's immune system mistakenly attacks and

destroys

the beta cells in the pancreas, leaving the patient with an absolute

dependency on an exogenous supply of insulin necessary for survival.

Type 2 results from a combination of insulin resistance and beta cell

defect. The latter point is subject to some debate, as some believe

that ongoing insulin resistance causes the beta cells to

effectively " burn out " from overexhaustion combined with inceased

rate

of beta cell aptosis (or cell death). However, some patients with

Type

2 actually require insulin supplementation, and their endogenous

insulin production is markedly below average. Regardless, most Type

2

patients have a relative, rather than an absolute insulin dependency.

This results in a risk of hypoglycemia being markedly lower for

insulin-

using Type 2 patients than it is for Type 1 patients.

The summary answer to this question is absolutely not, both Type 1

and

Type 2 are serious, although different, conditions.

I am wondering if the diabetes required insulin treatment is more

serious kind than the one treated with oral medication.

Thank you.

________________________________________________________________

Sent via the WebMail system at phreego.com

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- I have to ask since you seem to have a good handle on the

different types of DM. Most of my pancreas was removed during surgery

for a pancreatic tumor. Does that make my DM autoimmune or insulin

resistance or something else, like just a plain lack of producing

sufficient insulin. Is there really any important difference? Inquiring

minds want to know.

Barb in NH

Strumello wrote:

> Type 1 and Type 2 are not the same condition -- the etiology for each

> are completely different and unrelated. Type 1 is an autoimmune

> disease, where the body's immune system mistakenly attacks and

> destroys

> the beta cells in the pancreas, leaving the patient with an absolute

> dependency on an exogenous supply of insulin necessary for survival.

>

> Type 2 results from a combination of insulin resistance and beta cell

> defect. The latter point is subject to some debate, as some believe

> that ongoing insulin resistance causes the beta cells to

> effectively " burn out " from overexhaustion combined with inceased

> rate

> of beta cell aptosis (or cell death). However, some patients with

> Type

> 2 actually require insulin supplementation, and their endogenous

> insulin production is markedly below average. Regardless, most Type

> 2

> patients have a relative, rather than an absolute insulin dependency.

>

> This results in a risk of hypoglycemia being markedly lower for

> insulin-

> using Type 2 patients than it is for Type 1 patients.

>

> The summary answer to this question is absolutely not, both Type 1

> and

> Type 2 are serious, although different, conditions.

>

> -

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- I have to ask since you seem to have a good handle on the

different types of DM. Most of my pancreas was removed during surgery

for a pancreatic tumor. Does that make my DM autoimmune or insulin

resistance or something else, like just a plain lack of producing

sufficient insulin. Is there really any important difference? Inquiring

minds want to know.

Barb in NH

Strumello wrote:

> Type 1 and Type 2 are not the same condition -- the etiology for each

> are completely different and unrelated. Type 1 is an autoimmune

> disease, where the body's immune system mistakenly attacks and

> destroys

> the beta cells in the pancreas, leaving the patient with an absolute

> dependency on an exogenous supply of insulin necessary for survival.

>

> Type 2 results from a combination of insulin resistance and beta cell

> defect. The latter point is subject to some debate, as some believe

> that ongoing insulin resistance causes the beta cells to

> effectively " burn out " from overexhaustion combined with inceased

> rate

> of beta cell aptosis (or cell death). However, some patients with

> Type

> 2 actually require insulin supplementation, and their endogenous

> insulin production is markedly below average. Regardless, most Type

> 2

> patients have a relative, rather than an absolute insulin dependency.

>

> This results in a risk of hypoglycemia being markedly lower for

> insulin-

> using Type 2 patients than it is for Type 1 patients.

>

> The summary answer to this question is absolutely not, both Type 1

> and

> Type 2 are serious, although different, conditions.

>

> -

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- I have to ask since you seem to have a good handle on the

different types of DM. Most of my pancreas was removed during surgery

for a pancreatic tumor. Does that make my DM autoimmune or insulin

resistance or something else, like just a plain lack of producing

sufficient insulin. Is there really any important difference? Inquiring

minds want to know.

Barb in NH

Strumello wrote:

> Type 1 and Type 2 are not the same condition -- the etiology for each

> are completely different and unrelated. Type 1 is an autoimmune

> disease, where the body's immune system mistakenly attacks and

> destroys

> the beta cells in the pancreas, leaving the patient with an absolute

> dependency on an exogenous supply of insulin necessary for survival.

>

> Type 2 results from a combination of insulin resistance and beta cell

> defect. The latter point is subject to some debate, as some believe

> that ongoing insulin resistance causes the beta cells to

> effectively " burn out " from overexhaustion combined with inceased

> rate

> of beta cell aptosis (or cell death). However, some patients with

> Type

> 2 actually require insulin supplementation, and their endogenous

> insulin production is markedly below average. Regardless, most Type

> 2

> patients have a relative, rather than an absolute insulin dependency.

>

> This results in a risk of hypoglycemia being markedly lower for

> insulin-

> using Type 2 patients than it is for Type 1 patients.

>

> The summary answer to this question is absolutely not, both Type 1

> and

> Type 2 are serious, although different, conditions.

>

> -

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Barb, I think you're in a class by yourself <g>

That is to say, diabetes caused by removal of the pancreas is neither

type 1 or 2. But since you have no pancreas and therefore no beta cells

produced, you're obviously closer to type 1. OTOH, you could also be

insulin resistant too, that's a completely different animal. But a lot

less likely.

Vicki

Re: Re: DM kinds

> - I have to ask since you seem to have a good handle on the

> different types of DM. Most of my pancreas was removed during surgery

> for a pancreatic tumor. Does that make my DM autoimmune or insulin

> resistance or something else, like just a plain lack of producing

> sufficient insulin. Is there really any important difference?

> Inquiring

> minds want to know.

>

> Barb in NH

>

> Strumello wrote:

>

>> Type 1 and Type 2 are not the same condition -- the etiology for each

>> are completely different and unrelated. Type 1 is an autoimmune

>> disease, where the body's immune system mistakenly attacks and

>> destroys

>> the beta cells in the pancreas, leaving the patient with an absolute

>> dependency on an exogenous supply of insulin necessary for survival.

>>

>> Type 2 results from a combination of insulin resistance and beta cell

>> defect. The latter point is subject to some debate, as some believe

>> that ongoing insulin resistance causes the beta cells to

>> effectively " burn out " from overexhaustion combined with inceased

>> rate

>> of beta cell aptosis (or cell death). However, some patients with

>> Type

>> 2 actually require insulin supplementation, and their endogenous

>> insulin production is markedly below average. Regardless, most Type

>> 2

>> patients have a relative, rather than an absolute insulin dependency.

>>

>> This results in a risk of hypoglycemia being markedly lower for

>> insulin-

>> using Type 2 patients than it is for Type 1 patients.

>>

>> The summary answer to this question is absolutely not, both Type 1

>> and

>> Type 2 are serious, although different, conditions.

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Barb, I think you're in a class by yourself <g>

That is to say, diabetes caused by removal of the pancreas is neither

type 1 or 2. But since you have no pancreas and therefore no beta cells

produced, you're obviously closer to type 1. OTOH, you could also be

insulin resistant too, that's a completely different animal. But a lot

less likely.

Vicki

Re: Re: DM kinds

> - I have to ask since you seem to have a good handle on the

> different types of DM. Most of my pancreas was removed during surgery

> for a pancreatic tumor. Does that make my DM autoimmune or insulin

> resistance or something else, like just a plain lack of producing

> sufficient insulin. Is there really any important difference?

> Inquiring

> minds want to know.

>

> Barb in NH

>

> Strumello wrote:

>

>> Type 1 and Type 2 are not the same condition -- the etiology for each

>> are completely different and unrelated. Type 1 is an autoimmune

>> disease, where the body's immune system mistakenly attacks and

>> destroys

>> the beta cells in the pancreas, leaving the patient with an absolute

>> dependency on an exogenous supply of insulin necessary for survival.

>>

>> Type 2 results from a combination of insulin resistance and beta cell

>> defect. The latter point is subject to some debate, as some believe

>> that ongoing insulin resistance causes the beta cells to

>> effectively " burn out " from overexhaustion combined with inceased

>> rate

>> of beta cell aptosis (or cell death). However, some patients with

>> Type

>> 2 actually require insulin supplementation, and their endogenous

>> insulin production is markedly below average. Regardless, most Type

>> 2

>> patients have a relative, rather than an absolute insulin dependency.

>>

>> This results in a risk of hypoglycemia being markedly lower for

>> insulin-

>> using Type 2 patients than it is for Type 1 patients.

>>

>> The summary answer to this question is absolutely not, both Type 1

>> and

>> Type 2 are serious, although different, conditions.

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No, Vicki, Barb still has some pancreas and this allows her to control

with small amounts of medication and controlled carbs. However, there

are other parts of the digestive system missing, so Barb's reaction to

foods do not fit the type 2 type of diabetes.

Barb, you have surgical-onset diabetes and while rare, are not alone. Of

course, since the surgeries are not all the same, the reactions and

treatments are different too. Your mileage varies even more.

But the feelings are the same; the desire to keep the disease at bay and

avoid complications, the care that must be taken when deciding what to

eat, the depression that can result and, somewhat, the medication used.

Helen

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