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Seldane, erythromycin, long QT syndrome and mito

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I was wondering if anyone had taken Seldane (allergy medication) in

the past (a while ago, it's now off the market). I was checking out

the wustl website, and it mentions long QT syndrome as related to a

Complex I disorder.

My muscle biopsy showed a Complex I disorder, and I had taken

Seldane, with erythromycin at some points, a while back. Now Seldane

is off the market, because of association with long QT syndrome.

Hopefully I didn't ask this before, I don't get a chance to read too

often and I have some Alzheimer-like symptoms so my memory isn't that

good sometimes.

I may contact the manufacturer about it, but I'd probably have to dig

up my old medical records.

Just wondering,

RH

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My son was on Seldane and erythromycin simultaneously for a couple

of years before the negative interactions of those two drugs were

known. During that time he did develop several abnormalities on his

EKG, including right bundle branch block. May have had long QT also--

I do remember something about T waves. The problem was discovered

incidently during exercise testing for a mito research study. I

still remember when the technician came out and asked me who his

pediatric cardiologist was, and I said I didn't know he needed one.

It was a bit of a shock. At the time, the abnormalities were put

down to mito, but they did all resolve later once he was off

Seldane.

Barbara

> I was wondering if anyone had taken Seldane (allergy medication)

in

> the past (a while ago, it's now off the market). I was checking

out

> the wustl website, and it mentions long QT syndrome as related to

a

> Complex I disorder.

>

> My muscle biopsy showed a Complex I disorder, and I had taken

> Seldane, with erythromycin at some points, a while back. Now

Seldane

> is off the market, because of association with long QT syndrome.

>

> Hopefully I didn't ask this before, I don't get a chance to read

too

> often and I have some Alzheimer-like symptoms so my memory isn't

that

> good sometimes.

>

> I may contact the manufacturer about it, but I'd probably have to

dig

> up my old medical records.

>

> Just wondering,

> RH

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