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Re: Vitamin E and toxicity

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I am interested in knowing about toxicity of too much vitamin E. Do

you have information you could point me to?

> Laurie,

> Wouldn't that be about 900 IU a day of vitamin E (3000 times the

> recommended dosage?)  If Dr. Cohen has tested you and is comfortable

> with that, then I guess I wouldn't worry.  After reading about the

> toxicity of too much vitamin E - my dosage concerned me.  Also, I

> believe I'm getting headaches from that level.

>

> Maggie

>

>

>

> > >> Beth... It's really great to hear from you today.  It has been a

> > > very long time and you've been missed.

> > >>

> > >> I'm curious about which type of CoQ most of you have purchased

> > > from Epic.  The only one of theirs I could try had vitamin E in

> it

> > > and there was way too much of it in there for me to take 1000 mg

> a

> > > day.

> > >>

> > >> Tishon is developing (but it is not out yet as it is still in

> > > trials) a 500 mg chewable that can be cut in quarters.  It does

> not

> > > have any vitamin E in it.  I wonder if this would be my answer. 

> Can

> > > you imagine.. 2 pills a day?

> > >>

> > >> Alice

> > >>

> > >>

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Drs. Cohen and Gold in " Treatment of Mitochondrial Cytopathies "

recommend vitamin E at 400 to 1200 IU per day in divided doses as

appropriate antioxidant therapy, given the excessive free radicals

that occur in mito disorders. In the latest UMDF newsletter, Dr.

Tarnopolsky recommends vitamin E at 250 to 500 mg twice daily or 10-

15 mg/kg/day.

This does not directly address your question about toxicity, but the

mito experts do feel these doses are generally safe.

Barbara

> > > >> Beth... It's really great to hear from you today.  It has

been a

> > > > very long time and you've been missed.

> > > >>

> > > >> I'm curious about which type of CoQ most of you have

purchased

> > > > from Epic.  The only one of theirs I could try had vitamin

E in

> > it

> > > > and there was way too much of it in there for me to take

1000 mg

> > a

> > > > day.

> > > >>

> > > >> Tishon is developing (but it is not out yet as it is still

in

> > > > trials) a 500 mg chewable that can be cut in quarters.  It

does

> > not

> > > > have any vitamin E in it.  I wonder if this would be my

answer. 

> > Can

> > > > you imagine.. 2 pills a day?

> > > >>

> > > >> Alice

> > > >>

> > > >>

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> From: z39z@...

> Reply-To:

> Date: Tue, 6 Apr 2004 13:01:14 -0400

> To:

> Subject: Re: Vitamin E and toxicity

>

>

> I am interested in knowing about toxicity of too much vitamin E. Do

> you have information you could point me to?

Vitamin E Toxicity

Adults have taken relatively large amounts of vitamin E (400 to 800 mg/day

of d--tocopherol) for months to years without any apparent harm.

Occasionally, muscle weakness, fatigue, nausea, and diarrhea have occurred

in persons taking 800 to 3200 mg/day. The most significant toxic effect of

vitamin E at > 1000 mg/day is antagonism to vitamin K action and enhancement

of the effect of oral coumarin anticoagulants, which may result in overt

hemorrhage.

This is from the Merck Manual which I consider a reliable souce. It is the

book doctors go to for information such as this.

laurie

>

>

>

>

>> Laurie,

>> Wouldn't that be about 900 IU a day of vitamin E (3000 times the

>> recommended dosage?)  If Dr. Cohen has tested you and is comfortable

>> with that, then I guess I wouldn't worry.  After reading about the

>> toxicity of too much vitamin E - my dosage concerned me.  Also, I

>> believe I'm getting headaches from that level.

>>

>> Maggie

>>

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Guest guest

I was worried about my 11 year old getting too much vitamin E also but the

dr that diagnosed our melas says the $450 mg he gets with the 3 qgel he

takes is safe.

Janet Sample

Re: Vitamin E and toxicity

Drs. Cohen and Gold in " Treatment of Mitochondrial Cytopathies "

recommend vitamin E at 400 to 1200 IU per day in divided doses as

appropriate antioxidant therapy, given the excessive free radicals

that occur in mito disorders. In the latest UMDF newsletter, Dr.

Tarnopolsky recommends vitamin E at 250 to 500 mg twice daily or 10-

15 mg/kg/day.

This does not directly address your question about toxicity, but the

mito experts do feel these doses are generally safe.

Barbara

> > > >> Beth... It's really great to hear from you today. It has

been a

> > > > very long time and you've been missed.

> > > >>

> > > >> I'm curious about which type of CoQ most of you have

purchased

> > > > from Epic. The only one of theirs I could try had vitamin

E in

> > it

> > > > and there was way too much of it in there for me to take

1000 mg

> > a

> > > > day.

> > > >>

> > > >> Tishon is developing (but it is not out yet as it is still

in

> > > > trials) a 500 mg chewable that can be cut in quarters. It

does

> > not

> > > > have any vitamin E in it. I wonder if this would be my

answer.

> > Can

> > > > you imagine.. 2 pills a day?

> > > >>

> > > >> Alice

> > > >>

> > > >>

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In a message dated 4/6/2004 11:11:23 PM Eastern Daylight Time,

z39z@... writes:

> > I am interested in knowing about toxicity of too much vitamin E. Do

> > you have information you could point me to?

I recently asked this same question b/c I take 1200 mg/day of Tishcon CoQ10

and I get almost 2000 IU's of Vitamin E a day through the Coq10. I asked both

my cardiologist who did Vitamin E research in cardiac disease for 11 yrs and

my IV nutrition dietician about how much is too much. Both said that studies

have been done with doses up to 2000 IU's a day and I should be okay. They did

recommend that I get my vitamin E level checked though to make sure it isn't

too high and also recommended having my PT and PTT checked since Vitamin E can

inhibit clotting and prolong the PT and PTT (clotting times).

Malisa

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Wow..I didn't mean to stir up so much with this subject. In my case...taking

1000 mg daily of CoQ the amount is 1500 IU which even Tishon feels is too much.

Alice

Re: Vitamin E and toxicity

Drs. Cohen and Gold in " Treatment of Mitochondrial Cytopathies "

recommend vitamin E at 400 to 1200 IU per day in divided doses as

appropriate antioxidant therapy, given the excessive free radicals

that occur in mito disorders. In the latest UMDF newsletter, Dr.

Tarnopolsky recommends vitamin E at 250 to 500 mg twice daily or 10-

15 mg/kg/day.

This does not directly address your question about toxicity, but the

mito experts do feel these doses are generally safe.

Barbara

> > > >> Beth... It's really great to hear from you today. It has

been a

> > > > very long time and you've been missed.

> > > >>

> > > >> I'm curious about which type of CoQ most of you have

purchased

> > > > from Epic. The only one of theirs I could try had vitamin

E in

> > it

> > > > and there was way too much of it in there for me to take

1000 mg

> > a

> > > > day.

> > > >>

> > > >> Tishon is developing (but it is not out yet as it is still

in

> > > > trials) a 500 mg chewable that can be cut in quarters. It

does

> > not

> > > > have any vitamin E in it. I wonder if this would be my

answer.

> > Can

> > > > you imagine.. 2 pills a day?

> > > >>

> > > >> Alice

> > > >>

> > > >>

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Guest guest

Thank you, for the reference on Vitamin E toxicity and the Merk

Manual, and thanks others for your experiences and views.

Regards

Sunny

>

>

> > From: z39z@...

> > Reply-To:

> > Date: Tue, 6 Apr 2004 13:01:14 -0400

> > To:

> > Subject: Re: Vitamin E and toxicity

> >

> >

> > I am interested in knowing about toxicity of too much vitamin E.  Do

> > you have information you could point me to?

>

>

>

> Vitamin E Toxicity

>

> Adults have taken relatively large amounts of vitamin E (400 to 800

> mg/day

> of d--tocopherol) for months to years without any apparent harm.

> Occasionally, muscle weakness, fatigue, nausea, and diarrhea have

> occurred

> in persons taking 800 to 3200 mg/day. The most significant toxic

> effect of

> vitamin E at > 1000 mg/day is antagonism to vitamin K action and

> enhancement

> of the effect of oral coumarin anticoagulants, which may result in

> overt

> hemorrhage.

>

> This is from the Merck Manual which I consider a reliable souce. It

> is the

> book doctors go to for information such as this.

>

> laurie

>

>

> >

> >

> >

> >

> >> Laurie,

> >> Wouldn't that be about 900 IU a day of vitamin E (3000 times the

> >> recommended dosage?)  If Dr. Cohen has tested you and is

> comfortable

> >> with that, then I guess I wouldn't worry.  After reading about the

> >> toxicity of too much vitamin E - my dosage concerned me.  Also, I

> >> believe I'm getting headaches from that level.

> >>

> >> Maggie

> >>

>

>

>

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>

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> the attack.

>

>

>

>

>

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