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Re: : Penicillian, Narcotics, ETC.

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Hi Myra, Thanks for explaining that. I guess what I am really wondering is

if a person (lets say with masto) can have no gastro troubles at all and

then take something like penicillian and then get gastro trouble which does

not end even if they discontinue the med. Can a few doses of penicillian

cause someone life long gastro problems? This is interesting to me,

inquiring minds want to know :o) Love,

: Penicillian, Narcotics, ETC.

> Hi ,

> Long time no talk... I guess we both have been up to our eyebrows...

> Anyway, the information which you quoted below... are listing some

> items which are " direct " mast cell degranulators.... What this means

> is that the mast cell does not have to have a number of antigens

> docking on IgE... they cause the mast cell to degranulate directly...

> Penicillian, narcotics, cocaine, contrast dye media, heat, cold,

> light can all directly degranulate mast cells... and this can happen

> rather quickly causing syncope (fainting), vascular collapse and

> anaphylaxis. The reason that gastrointestinal symptoms would be

> precipated by these is H2. Hope this helps, Love Myra

>

>

> Some studies show that gastrointestinal symptoms are precipitated

> with drugs such as penicillin, narcotics, cocaine, aspirin,

> nonsteroidal anti-inflammatory drugs (NSAIDs), and Persantin. These

> drugs also can provoke anaphylaxis, vascular collapse, or syncope.

>

>

>

>

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