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Re: Policosanol test

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In a message dated 8/16/2005 2:04:58 PM Eastern Standard Time,

staceypmartin@... writes:

> did you try policosanol after stopping a statin to see if the policosanol

> would work as well, or did you just try the policosanol with the lower

> numbers after not being on a statin and find that your numbers went up with

it?

The latter. I was never on a statin and tried the policosanol as a means to

lower my numbers. Policosanol had the opposite effect of what I had expected.

It made my numbers considerably worse.

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In a message dated 8/16/2005 3:10:51 PM Eastern Standard Time,

gretchen@... writes:

> Wasn't this the period during which you went to the hospital and had a

> stent inserted? I'm sure this affected your physiology. For instance, I

suspect

> the hospital didn't include Merlot on the menu, and you were probably getting

> different drugs.

All true, but I had the cholesterol tests about 25 days after discontinuing

the other meds and restarting the Merlot. I'm going to get a meter to do my own

testing of the lipids.

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In a message dated 8/16/2005 5:00:38 PM Eastern Standard Time,

marysue@... writes:

> Why don't you want to take a statin, ? Since you've already had

> cardiovascular problems, it couldn't hurt, could it?

A good question, Sue.

I've read about the impact of statins on muscles and because of polio I'm

very concerned about anything that might adversely effect my muscle function.

It's all a trade off. A small station dose may be worth a test, if all else

fails.

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Were you doing any other things differently? Wasn't this the period during

which you went to the hospital and had a stent inserted? I'm sure this

affected your physiology. For instance, I suspect the hospital didn't

include Merlot on the menu, and you were probably getting different drugs.

Gretchen

> Well, I finally got my results from using policosanol. Not good, but at

least

> it was a test . . . now discontinued :)

>

> TOTAL = 236 was 215

>

> LDL = 162 was 113

>

> HDL = 76 was 89

>

>

>

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Why don't you want to take a statin, ? Since you've already had

cardiovascular problems, it couldn't hurt, could it? Sue

>

> The latter. I was never on a statin and tried the policosanol as a

> means to

> lower my numbers. Policosanol had the opposite effect of what I had

> expected.

> It made my numbers considerably worse.

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In a message dated 8/17/2005 7:34:53 PM Eastern Standard Time,

andreafrankel@... writes:

> One thing to try first is Red Yeast Rice (I use Doctor's Best brand from

> iherb.com). It has a low level of natural lovastatin, along with other stuff,

> and by taking 2 capsules twice a day, I was able to bring my total

> cholesterol down from over 240 to 181 in about 6 months. (Could have been

sooner, but

> that's when I was retested.) Again, supplement

> with CoQ10.

That's a great result, , (el) Thanks for the suggestion. Because

of PPS I have to be very concerned about muscle loss.

I'll be testing about once a month, therefore positive or negative results

with any new protocol should be apparent fairly quickly. The first step is to

wash out the policosanol effects and establish a new unmedicated reference

condition.

Cheers,

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> > Numerically, close Gretchen. My triglycerides were 57.

>

> I think Total Cholesterol = HDL + LDL + TG/5.

>

> So something is wrong.

>

> Gretchen

That was also my understanding. However, a directly measured LDL can

be different to calculated - but that's a big difference in 's

case.

His measured LDL was 162. With a total of 236, HDL of 76 (excellent

btw) and trigs of 57 - also excellent, calculated LDL would be 149

compared with 162 measured.

With that low trigs level and a trigs/HDL ratio of 0.75 (indicating

low insulin resistance) I wouldn't have been very concerned if it was

me; however I haven't had heart surgery so I can understand that the

doc's would be looking for low LDL. In the circumstances, I suspect

VLDL would be quite low and most of the LDL is fluffy.

These are all guesses based on reading, not expertise - so don't take

much notice, just musing.

Cheers, Alan, T2 d & e, Australia

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DEKEP@... wrote:

> In a message dated 8/16/2005 5:00:38 PM Eastern Standard Time,

> marysue@... writes:

>

> > Why don't you want to take a statin, ? Since you've already had

> > cardiovascular problems, it couldn't hurt, could it?

>

> A good question, Sue.

>

> I've read about the impact of statins on muscles and because of polio I'm

> very concerned about anything that might adversely effect my muscle

> function.

> It's all a trade off. A small station dose may be worth a test, if all

> else

> fails.

If you have PPS, I'd be very, very cautious about taking a statin. You

run the risk of losing more muscle function, permanently. If you do

decide to, you will definitely need to supplement with CoQ10, 100 mg up

to 300 mg a day.

One thing to try first is Red Yeast Rice (I use Doctor's Best brand from

iherb.com). It has a low level of natural lovastatin, along with other

stuff, and by taking 2 capsules twice a day, I was able to bring my

total cholesterol down from over 240 to 181 in about 6 months. (Could

have been sooner, but that's when I was retested.) Again, supplement

with CoQ10.

I do not have PPS, but I do have CFS with fibromyalgia. I tried a

statin, and by the second day my muscles were starting to show alarming

weakness plus muscle pain. Needless to say, I stopped taking the statin

right away. But I do not have that problem with the Red Yeast Rice.

--

el (andreafrankel at sbcglobal dot net)

" wake now! Discover that YOU are the song that the morning brings... "

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Prior to going on a statin, my cholesterol was not bad

-- for a non-diabetic.Total 202. But LDL was 98 and

HDL 96/great ratio, Trig 89. However, my PCP wanted

me to try to get the LDL down to 70. So, I started

taking 10 mg/day of Lipitor. It worked--got LDL down

to 73 without change in diet. Also, gained close to 20

pounds in 3 months without change in diet. Couldn't

figure it out. Thought I might be eating more. So,

cut back on food. Next 3 months gained 15 pounds

even though carefully watched portions. (Yikes! Gained

35 pounds of the 50 I so carefully lost over a

year!)PCP ran tests and found I was sub-clinical

hypothyroid. Also took me off Lipitor because all

statins can cause weight gain. I'm now taking 75

mcg/day of Synthroid. We will see what happens over

next 3-6 months with regard to my weight loss. She

is not keen on me trying a statin again but would like

to try Niaspan again (which can increase insulin

resistance--and did in me). We will see.... Since by

BG is within normal range (last A1c 5.5), my BP is

90/60, if my weight normalizes again (actually I was

about 40 pounds overweight and losing at about a pound

a week before the Lipitor experience), I'm not sure I

really need to lower my LDL given my total chol level

and my ratio. They say all diabetics should be treated

as if they have heart disease but with labs like mine

and being so well-controlled, I wonder. Your thoughts?

Alyne T2, Dx 8-03, D & E and Metformin

__________________________________________________

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