11 years later and most doctors still unaware...

[Guest guest]

For those of you who understand a bit more about the cellular level of CF (or

the body in general) the following article may make more sense to you. But

please take the time to read this; it could make all the difference in your

health, your child's health or that of a friend or relative. If you have free

time you might want to explore this topic more -- there is so much

information out there. This article reinforces that blood tests showing

" normal " magnesium levels does not mean there isn't a deficiency.

--Kim

The role of magnesium in clinical biochemistry: an overview.

Ann Clin Biochem, 78(2):19-26 1991 Jan

Magnesium is the second most abundant intracellular cation. It is essential

for a wide variety of metabolically important reactions, in particular those

involving ATP. Hypomagnesaemia is surprisingly common in hospital populations

but is sometimes either undetected or overlooked. Serum magnesium

concentrations provide a guide to magnesium status but while hypomagnesaemia

is a reliable indicator of magnesium deficiency, normomagnesaemia does not

exclude magnesium depletion. A wide variety of conditions predispose to

magnesium depletion. Clinical magnesium deficiency has potentially fatal

consequences in vulnerable groups of patients and should be excluded in all

such cases. Magnesium deficiency may result in hypokalaemia, hypocalcaemia or

other disturbances of electrolyte homeostasis, refractory cardiac

arrhythmias, or increased sensitivity to digoxin. The capacity to measure

serum and urine magnesium concentrations rapidly, regularly and reliably

should be part of the repertoire of all clinical chemistry laboratories

involved in the care of critically ill patients.

[Guest guest]

Hi Kim,

thnaks for all those valuable you're sending. I am unsure about a

direct correlation between CF and magnesium deficiency, but since CF

causes such a complex metabolic disorder in the body, I highly

recommend that all pwcf get a large bloodwork done once a year to

check for all vitamins and minerals.

Peace

Torsten, dad of Fiona 5wcf

> For those of you who understand a bit more about the cellular level

of CF (or

> the body in general) the following article may make more sense to

you. But

> please take the time to read this; it could make all the difference

in your

> health, your child's health or that of a friend or relative. If you

have free

> time you might want to explore this topic more -- there is so much

> information out there. This article reinforces that blood tests

showing

> " normal " magnesium levels does not mean there isn't a deficiency.

> --Kim

>

> The role of magnesium in clinical biochemistry: an overview.

>

> Ann Clin Biochem, 78(2):19-26 1991 Jan

>

> Magnesium is the second most abundant intracellular cation. It is

essential

> for a wide variety of metabolically important reactions, in

particular those

> involving ATP. Hypomagnesaemia is surprisingly common in hospital

populations

> but is sometimes either undetected or overlooked. Serum magnesium

> concentrations provide a guide to magnesium status but while

hypomagnesaemia

> is a reliable indicator of magnesium deficiency, normomagnesaemia

does not

> exclude magnesium depletion. A wide variety of conditions

predispose to

> magnesium depletion. Clinical magnesium deficiency has potentially

fatal

> consequences in vulnerable groups of patients and should be

excluded in all

> such cases. Magnesium deficiency may result in hypokalaemia,

hypocalcaemia or

> other disturbances of electrolyte homeostasis, refractory cardiac

> arrhythmias, or increased sensitivity to digoxin. The capacity to

measure

> serum and urine magnesium concentrations rapidly, regularly and

reliably

> should be part of the repertoire of all clinical chemistry

laboratories

> involved in the care of critically ill patients.