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methotrexate side effects

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Hi Everyone,

I have a question about metho.I have uctd with high

suspicion of lupus. I had positive ana and sed rate,

positive crp but no blood markers yet. I started

metho 3 weeks ago, 5 tablets once a week. The first

week, I didn't feel much different. The second week,

I was a little tired. The third week, major fatigue,

major joint and muscle pain, swollen face. I don't

know if it is a flare or side effects. I have put off

3 days just not wanting to have to get ready to go and

drive to the pharmacy to pick up meds. Hubby gets

home too late to go. I have appt. with rheumy and

instructions to get bloodwork before next appt which

is next week. I just figured it was side effects. I

should also tell you that I take plaquenil twice a day

and prednisone 5 mg. every other day.

My question is, how long did it take you to get rid

of these side effects and for the methotrexate to kick

in and work? Thanks, Georgia

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Hey Georgia. I was just reading some of the side effects of methotrexate and I don't see where it lists some of the effects you are having. Maybe you should call the dr to make sure your not having an allergic reaction to it.

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