Guest guest Posted October 24, 2005 Report Share Posted October 24, 2005 Hi Pierre, It's the inquistive one here with some questions for you. 1. How many mg does 0.2g protein/day equal? 2. What does HbA1C mean when it's elevated in a urinalysis? 3. Is a urine protein/ creatinine ratio of 1.7 good or bad? 4. Is a urine dipstick result for protein of 30mg anything to be concerned about? 5. If a patient presents with hematuria but no loss in kidney function and then years down the road they develop the urine protein, how does a doctor differentiate the hematuria being from something else verses a symptom of kidney disease? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 0.2 grams per day is 200 mg. If that's protein per day (in a 24 hour urine collection, that's higher than normal range, but still very low). HbA1C is for diabetes. I'm not familiar with it myself. A protein/creatinine ratio of 1.7 is on the high side of moderate. It could be better. Some nephs might want to actively lower it. I don't know about the urine dipstik result. It really doesn't mean anything given the protein/creatinine ratio you already have which is way more meaningful. As to question #5: Well, they would never know for sure, except if the hematuria shows red blood cell casts. When there are red blood cell casts, you know the blood is from the glomerulonephritis, but these may not necessarily be there even if it is. If they aren't, you just don't know. You assume it's from the kidneys, but it could just as easily be from somewhere else in the urinary tract. This is one reason many people intially end up with a urologist performing a cystoscopy. Pierre Pierre > Hi Pierre, > > It's the inquistive one here with some questions for you. > > 1. How many mg does 0.2g protein/day equal? > 2. What does HbA1C mean when it's elevated in a urinalysis? > 3. Is a urine protein/ creatinine ratio of 1.7 good or bad? > 4. Is a urine dipstick result for protein of 30mg anything to be concerned > about? > 5. If a patient presents with hematuria but no loss in kidney function and > then years > down the road they develop the urine protein, how does a doctor > differentiate > the hematuria being from something else verses a symptom of kidney > disease? > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 Pierre as usual was dead keen, with the exception of HbA1C.....which a) has no meaning as measured in urine (even if you could easily, which you can't) and is the glycosylated hemoglobin product of glucose condensation with native hemoglobin (via the Malliard browning reaction....same one you use to make a roux for gravy with flour (starch) & butter (fat and protein)). Pierre is dead right this is for diabetes.....high blood sugar levels over time lead to more HbA1C than " normal, " and provide a historical perspective (out to 180 days or so) as to how long an individual might have had high blood sugar. 180 days being the lifetime of an RBC in normal circulation (btw, for us with poor kidney function, we get anemic via two mechanisms....myelosuppression from urea (derivatives of which have been used for years on cancer victims) and accelerated RBC destruction). As usual, more than anyone wanted to know Cheers, Bart Re: Pierre 0.2 grams per day is 200 mg. If that's protein per day (in a 24 hour urine collection, that's higher than normal range, but still very low). HbA1C is for diabetes. I'm not familiar with it myself. A protein/creatinine ratio of 1.7 is on the high side of moderate. It could be better. Some nephs might want to actively lower it. I don't know about the urine dipstik result. It really doesn't mean anything given the protein/creatinine ratio you already have which is way more meaningful. As to question #5: Well, they would never know for sure, except if the hematuria shows red blood cell casts. When there are red blood cell casts, you know the blood is from the glomerulonephritis, but these may not necessarily be there even if it is. If they aren't, you just don't know. You assume it's from the kidneys, but it could just as easily be from somewhere else in the urinary tract. This is one reason many people intially end up with a urologist performing a cystoscopy. Pierre Pierre > Hi Pierre, > > It's the inquistive one here with some questions for you. > > 1. How many mg does 0.2g protein/day equal? > 2. What does HbA1C mean when it's elevated in a urinalysis? > 3. Is a urine protein/ creatinine ratio of 1.7 good or bad? > 4. Is a urine dipstick result for protein of 30mg anything to be concerned > about? > 5. If a patient presents with hematuria but no loss in kidney function and > then years > down the road they develop the urine protein, how does a doctor > differentiate > the hematuria being from something else verses a symptom of kidney > disease? > > > > To edit your settings for the group, go to our Yahoo Group home page: http://groups.yahoo.com/group/iga-nephropathy/ To unsubcribe via email, iga-nephropathy-unsubscribe Visit our companion website at www.igan.ca. The site is entirely supported by donations. If you would like to help, go to: http://www.igan.ca/id62.htm Thank you Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 Thanks, Bart - I had wondered why, during the time my son had prednisone induced diabetes, they were so eager to monitor glycosylated hemoglobin. Now I know... Betsy > Pierre as usual was dead keen, with the exception of > HbA1C.....which a) has > no meaning as measured in urine (even if you could easily, which > you can't) > and is the glycosylated hemoglobin product of glucose > condensation with > native hemoglobin (via the Malliard browning reaction....same one > you use to > make a roux for gravy with flour (starch) & butter (fat and protein)). > > Pierre is dead right this is for diabetes.....high blood sugar > levels over > time lead to more HbA1C than " normal, " and provide a historical > perspective > (out to 180 days or so) as to how long an individual might have had > high > blood sugar. > > 180 days being the lifetime of an RBC in normal circulation (btw, > for us > with poor kidney function, we get anemic via two > mechanisms....myelosuppression from urea (derivatives of which have > been > used for years on cancer victims) and accelerated RBC destruction). > > As usual, more than anyone wanted to know > > Cheers, Bart > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 A;though Bart gave an unbelievable description, may I place it in layman;s terms. HbA1C or just A1C is the defining number us diabetics live and die by. It tells us the long term (180 days) control of our sugars. A simple blood glucose (BG) is just a snapshot. And a normal BG should be between 80-120. And to be honest, because I am on insulin, I can make a single BG anything I want for my labwork An A1C is done every 3 months. A simple example is as follows: a non-diabetic should have an A1c under 6. 6=an average blood sugar of 120. . 7=an average blood sugar of 150. 8=an average blood sugar of 180 9=an average blood sugar of 210 10=an average blood sugar of 240 Also, a nickname for this test amongst us diabetics is the " cheat test " . If you tell your Dr you are checking your sugars regularly and that they are normal (80-120), and you have this test and it comes back 8.8, he knows you are lying. Sharon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 HbA1C is a measurement of your sugar level over a period of time. My husband has diabetes and He will usually get this blood test done every 3 months. I can not remember what the ranges are for normal and high though, I'm sorry. Pam Pierre Lachaine pgl-groups@...> wrote: 0.2 grams per day is 200 mg. If that's protein per day (in a 24 hour urine collection, that's higher than normal range, but still very low). HbA1C is for diabetes. I'm not familiar with it myself. A protein/creatinine ratio of 1.7 is on the high side of moderate. It could be better. Some nephs might want to actively lower it. I don't know about the urine dipstik result. It really doesn't mean anything given the protein/creatinine ratio you already have which is way more meaningful. As to question #5: Well, they would never know for sure, except if the hematuria shows red blood cell casts. When there are red blood cell casts, you know the blood is from the glomerulonephritis, but these may not necessarily be there even if it is. If they aren't, you just don't know. You assume it's from the kidneys, but it could just as easily be from somewhere else in the urinary tract. This is one reason many people intially end up with a urologist performing a cystoscopy. Pierre Pierre > Hi Pierre, > > It's the inquistive one here with some questions for you. > > 1. How many mg does 0.2g protein/day equal? > 2. What does HbA1C mean when it's elevated in a urinalysis? > 3. Is a urine protein/ creatinine ratio of 1.7 good or bad? > 4. Is a urine dipstick result for protein of 30mg anything to be concerned > about? > 5. If a patient presents with hematuria but no loss in kidney function and > then years > down the road they develop the urine protein, how does a doctor > differentiate > the hematuria being from something else verses a symptom of kidney > disease? > > > > To edit your settings for the group, go to our Yahoo Group home page: http://groups.yahoo.com/group/iga-nephropathy/ To unsubcribe via email, iga-nephropathy-unsubscribe Visit our companion website at www.igan.ca. The site is entirely supported by donations. If you would like to help, go to: http://www.igan.ca/id62.htm Thank you Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 Hi Betsy, After your son was off the prednisone did the diabetes go away? My husband has diabetes and I am worried about it. I have been on Prednisone almost two months now and my Neph has ne scheduled for blood test next week and is testing for diabetes also. I was unaware that it was a side effect of the pred up until then. Pam c.com> wrote: Thanks, Bart - I had wondered why, during the time my son had prednisone induced diabetes, they were so eager to monitor glycosylated hemoglobin. Now I know... Betsy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 Well taken Tigger I do run along at the mouth and miss the point sometimes Bart Re: Pierre A;though Bart gave an unbelievable description, may I place it in layman;s terms. HbA1C or just A1C is the defining number us diabetics live and die by. It tells us the long term (180 days) control of our sugars. A simple blood glucose (BG) is just a snapshot. And a normal BG should be between 80-120. And to be honest, because I am on insulin, I can make a single BG anything I want for my labwork An A1C is done every 3 months. A simple example is as follows: a non-diabetic should have an A1c under 6. 6=an average blood sugar of 120. . 7=an average blood sugar of 150. 8=an average blood sugar of 180 9=an average blood sugar of 210 10=an average blood sugar of 240 Also, a nickname for this test amongst us diabetics is the " cheat test " . If you tell your Dr you are checking your sugars regularly and that they are normal (80-120), and you have this test and it comes back 8.8, he knows you are lying. Sharon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 Pam, He was on high dosage prednisone after a flare-up, and as the dosage was tapered down, the diabetes went away. Af first he was injecting insulin, then he just took Avandia, and then finally was able to stop the Avandia. Not everyone is so sensitive to prednisone, but he apparently is one of the unlucky ones. Betsy > Hi Betsy, > > After your son was off the prednisone did the diabetes go away? My > husband has diabetes and I am worried about it. I have been on > Prednisone almost two months now and my Neph has ne scheduled for > blood test next week and is testing for diabetes also. I was > unaware that it was a side effect of the pred up until then. > > Pam > Quote Link to comment Share on other sites More sharing options...
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