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Re: oxalate theory

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Clive Solomons a physican researcher is who came up with this theory

many years ago. The Vulvar Pain Foundation

http://www.vulvarpainfoundation.org/vpfnewsletter.htm is a grassroots

organization that supports and promotes a low oxalate diet and

CaCitrate to bind oxalates as a effective treatment. Oxalates are

needlelike in structure similar to the fibers in thistles and it is

believed that the oxalates are irritating to the vulvar tissue and

aggravate the surrounding areas of the urethra when excreted in the

urine. Calcium citrate is supposed to bind the oxalates so they can be

excreted without this irriation and over time allow the tissue to

heal. He also relates oxalates to " burning tongue " syndrome as a

similar condition. I don't think anyone knows why the body becomes

over sensitive to the oxalates. I met him at a Vulvar pain seminar.

Very nice gentle man.

>

> Just wondering if anyone has read why the oxalates in urine process

starts.

> I am thinking that high oxalates in my urine may be a contributing

factor to

> my pain, but wonder why this starts? Does anyone know?

>

> C

> **************New year...new news. Be the first to know what is

making

> headlines. (http://www.aol.com/?ncid=emlcntaolcom00000026)

>

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Just to throw my 2cents in : I started the calcitrate supplements and the calendula/estrace cream and have noticed a HUGE difference as far as my level of discomfort/pain- it has only been a couple of weeks now so i am hoping for greater improvement in the weeks to come. I have been a sufferer for years and decided to try this treatment since I had nothing to lose!

KL

Subject: Re: oxalate theoryTo: VulvarDisorders Date: Monday, January 5, 2009, 9:35 PM

Clive Solomons a physican researcher is who came up with this theory many years ago. The Vulvar Pain Foundation http://www.vulvarpa infoundation. org/vpfnewslette r.htm is a grassroots organization that supports and promotes a low oxalate diet and CaCitrate to bind oxalates as a effective treatment. Oxalates are needlelike in structure similar to the fibers in thistles and it is believed that the oxalates are irritating to the vulvar tissue and aggravate the surrounding areas of the urethra when excreted in the urine. Calcium citrate is supposed to bind the oxalates so they can be excreted without this irriation and over time allow the tissue to heal. He also relates oxalates to "burning tongue" syndrome as a similar condition. I don't think anyone knows why the body becomes over sensitive to the oxalates. I

met him at a Vulvar pain seminar. Very nice gentle man.>> Just wondering if anyone has read why the oxalates in urine process starts. > I am thinking that high oxalates in my urine may be a contributing factor to > my pain, but wonder why this starts? Does anyone know?> > C> ************ **New year...new news. Be the first to know what is making > headlines. (http://www.aol. com/?ncid= emlcntaolcom0000 0026)>

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http://en.wikipedia.org/wiki/Oxalobacter_formigenes

Oxalobacter formigenes is an oxalate-degrading anaerobic bacterium

that colonizes the large intestine in humans. While the human colon is

normally cultivated by these bacteria, they can be lost due to

antibiotic treatment with quinolones (however, not penicillin or

Bactrim). In people lacking the bacterium, calcium oxalate is not

degraded in the intestinal tract, and kidney stones can recur.[1]

Research is being conducted on its use as a treatment to prevent the

formation of calcium-oxalate kidney stones.

Also see:

http://www.oxthera.com/pr.php?no=0

Oxthera is a product which has been researched and hopefully will

replace the oxalobacter formigenes in the gut,

Ora

>Just wondering if anyone has read why the oxalates in urine process starts.

>I am thinking that high oxalates in my urine may be a contributing factor to

>my pain, but wonder why this starts? Does anyone know?

>

>C

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This might be interesting.

http://www.greatplainslaboratory.com.../oxal-test.pdf

and

http://www.lowoxalate.info/

and

The following is a quote and also a comment from a poster on a forum:

Quote:

Where do oxalates come from?

Oxalates are present in a lot of plants and fruit that we eat and in virtually

all seeds and nuts. Ordinarily, the gut won't absorb much of the oxalate from

the diet, and the oxalate will be metabolized by the flora or just leave the

body with the stool. Under other conditions, a lot of the dietary oxalate is

absorbed. Overabsorption is far more likely to occur when the tight junctions

between the cells which line the gut open up and let molecules pass through

between the cells in a condition called the " leaky gut " which is similar to a

condition in the bladder with open junctions called the " leaky bladder " .

comment:

And WHY do people have " tight junction dysfunction, " as Dr. Alessio Fasano

states in his PubMed studies? It's all due to gluten/gliadin! So oxalates are

harmless UNLESS we have a leaky gut. Or that's what I'm getting here...

(The leaky gut is caused by the damage gluten causes in the gut apparently

according to Dr. Fassano, who is a well known doctor and author in this field.)

Arline

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I was metabolizing oxalates better when I was on liver herbs

(although those gave me a lot of problems too, so I don't recommend

herbs for those of us with vulvodynia sicne we are very sensitive

people.) I got an oxalate problem after antibiotics, so the

oxalobacter theory seemed correct to me, but as I said, I wasn't

nearly as effected when I was taking herbs. So I think it's more of

just a detox problem.

>

> This might be interesting.

>

> http://www.greatplainslaboratory.com.../oxal-test.pdf

>

> and

>

> http://www.lowoxalate.info/

>

> and

>

> The following is a quote and also a comment from a poster on a

forum:

>

>

>

>

> Quote:

> Where do oxalates come from?

>

> Oxalates are present in a lot of plants and fruit that we eat and

in virtually all seeds and nuts. Ordinarily, the gut won't absorb

much of the oxalate from the diet, and the oxalate will be

metabolized by the flora or just leave the body with the stool. Under

other conditions, a lot of the dietary oxalate is absorbed.

Overabsorption is far more likely to occur when the tight junctions

between the cells which line the gut open up and let molecules pass

through between the cells in a condition called the " leaky gut " which

is similar to a condition in the bladder with open junctions called

the " leaky bladder " .

>

> comment:

> And WHY do people have " tight junction dysfunction, " as Dr. Alessio

Fasano states in his PubMed studies? It's all due to gluten/gliadin!

So oxalates are harmless UNLESS we have a leaky gut. Or that's what

I'm getting here...

>

> (The leaky gut is caused by the damage gluten causes in the gut

apparently according to Dr. Fassano, who is a well known doctor and

author in this field.)

>

> Arline

>

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