INHERITED? AGGIE, LETS Talk

[Guest guest]

Hi everyone, I was wondering if anyone knew if IGA Neph. is

inherited or Could I possible pass it on to my Child or future

children ?

Also I have been diagn with Kidney disiese for over 6 yr.s

my latest Creatine was 2.0 last month with a blood test performed by

my Dr. What Stage is that considered Stage 3 ? if so what could

possible be my current kidney Function ? 50% 60 70 ?? does anyone

have a clue ?

I may be going to get a biopsy soon to confirm my IGA diagnoses.

My nephrologist suspects this after noticing red blood cells in my

urine sample at my last visit a few days ago.

I feel great most of the time, try to exercise ie a recumbent bike &

treadmill, along with light weights, stetches and sit-ups.

and I have been eating less Sat fats less sodium and and more lowfat

veget. types of food. I still could do better but I'm excited about

losing some weight and feeling better & looking better.

I must also add that my mother died when I was a year and 1/2 years

old of Lupus, the dr. seems to think that I probably do not have

that since males tend to have it rarely passed to them ? any

feedback on this would be appreciated.

I hope I did not seem tooo long winded. I am from Texas

home of Texas ATM University is anyone ever been around these parts

I'm 38 and have been here my whole life, I have been married

since '92 and we have a son who's 6 going into the first grade, he's

a card and such a blessing, speaking of blessings are there any

belivers in the Lord out there ? write me if you can, I have so many

emotional ups and downs trying to make heads or tails of this

Diseise.

[Guest guest]

Hi there,

It is my understanding that IgAN is not a hereditery disease, but someone who

knows more about the disease will have to confirm this. As well, I do not think

you pass it along to your children.

Stage 3 starts when you have a moderately lowered GFR (30-59 ml/min). In order

to find out your GFR you would have to ask your doctor or use one of the online

calculators with your information. Creatinine normally decreases with age but

when it continually delcines it's an indicator of kidney disease. Someone in

the group once told me that roughly 2.0mg of creatinine is equivalent to 50%

function.

I as well have not had a biopsy to confirm my doctor's suspicions, but I have

been told that microscopically examining my urine, it was found that I had many

red blood cells and cast, some of which were red blood cell casts.

I am not familiar with Lupus, so perhaps someone else is and can help you out

there. I've never been to Texas but I am married with 2 girls and yes I believe

in the Lord. Michigan is my home but I live in Toronto, Canada.

[Guest guest]

Thank you so much for writing me back, I see your name on the posts all the

time. So how long have you had CKD ? Its great to talk to so to speak to another

person with some things in common not just Kidney disfunction. are you a

moderator on this web-service ? are you maybe going to get a biopsy ? Its rainy

here in Texas.

angeldragonfly@...> wrote:Hi there,

It is my understanding that IgAN is not a hereditery disease, but someone who

knows more about the disease will have to confirm this. As well, I do not think

you pass it along to your children.

Stage 3 starts when you have a moderately lowered GFR (30-59 ml/min). In order

to find out your GFR you would have to ask your doctor or use one of the online

calculators with your information. Creatinine normally decreases with age but

when it continually delcines it's an indicator of kidney disease. Someone in

the group once told me that roughly 2.0mg of creatinine is equivalent to 50%

function.

I as well have not had a biopsy to confirm my doctor's suspicions, but I have

been told that microscopically examining my urine, it was found that I had many

red blood cells and cast, some of which were red blood cell casts.

I am not familiar with Lupus, so perhaps someone else is and can help you out

there. I've never been to Texas but I am married with 2 girls and yes I believe

in the Lord. Michigan is my home but I live in Toronto, Canada.

[Guest guest]

Great response - I just wanted to add a couple notes:

Creatinine Clearance declines with loss of kidney function. Serum

Creatinine will increase with loss of kidney function. Creatinine is a

by-product that is removed by the kidneys, hence a decline in kidney

function will allow more creatinine to accumulate in the blood as it is

not being removed by the kidneys. Its important to keep in mind that day

to day serum creatinine levels can fluctuate depending on many factors

(hydration level, physical exertion, diet). The GFR calculated from that

serum creatinine also depends on other factors like size, gender and

muscle mass, so it is difficult to estimate without factoring those in.

Other people have posted web links that have calculator for GFR, but I

don't have it offhand. A 24hr collection is needed to get a better

estimate for GFR from the creatinine clearance.

Also, as far as I understand, IgAN is not believed to be hereditary,

although there is believed to be some genetic component. This is

evidenced by an uneven distribution of cases among different ethnic

backgrounds.

-

angeldragonfly@...>

Sent by: iga-nephropathy

08/10/2005 03:36 PM

Please respond to iga-nephropathy

To: iga-nephropathy

cc:

Subject: Re: INHERITED? AGGIE, LETS Talk

Hi there,

It is my understanding that IgAN is not a hereditery disease, but someone

who knows more about the disease will have to confirm this. As well, I do

not think you pass it along to your children.

Stage 3 starts when you have a moderately lowered GFR (30-59 ml/min). In

order to find out your GFR you would have to ask your doctor or use one of

the online calculators with your information. Creatinine normally

decreases with age but when it continually delcines it's an indicator of

kidney disease. Someone in the group once told me that roughly 2.0mg of

creatinine is equivalent to 50% function.

I as well have not had a biopsy to confirm my doctor's suspicions, but I

have been told that microscopically examining my urine, it was found that

I had many red blood cells and cast, some of which were red blood cell

casts.

I am not familiar with Lupus, so perhaps someone else is and can help you

out there. I've never been to Texas but I am married with 2 girls and yes

I believe in the Lord. Michigan is my home but I live in Toronto, Canada.

[Guest guest]

It's a rainy day here in Toronto as well and very humid.

You see my name on posts all the time because I'm new here and trying to learn

all the in's and out's of this disease without overloading my brain on medical

terms and 'what if's'. No, I am not a moderator, far far from it. I know

Pierre and are moderators, who else I haven't learned that yet.

I have been assumed to have IgAN for just over 4 years now. I often wonder

though if it has been with me since I was a teenager, with having the blood in

urine. As I'm told this is a relatively new disease in the medical world and

there are alot of doctors unfamiliar with it, so who knows.

I am going to ask my nephrologist at my next appointment about a biopsy as that

would confirm whether I actually do have IgAN or some other form of kidney

disease. I am followed every 6 months. I guess you don't know how often you'll

see your nephrologist yet?

Keep us posted when you do and don't hesitate to ask questions, we're all here

to help each other.

)

[Guest guest]

Ha Ha! Someone hasn't read www.igan.ca :-)

Most of what we know about whether IgAN is hereditary or not is posted on

http://www.igan.ca/id43.htm . Anything beyond that is going to be

speculation.

There are a number of IgAN longtimers on here who have children of adult

age. None of the kids inherited the IgAN, but, you never know what the

future holds. My eldest is the same age I was when they first detected signs

of a kidney problem.

Pierre

[Guest guest]

Hi fellow Texan! I lived in Tyler, Tx for 19 yrs. Moved back to

Oregon in 2003. I believe in the Lord and miss the Southern Baptist

church we used to belong to!! My 11 yr old son was diagnosed with

Igan in July. I more than he have dealt with the ups and downs and

even being angry with God, so I understand. Blade has really taken

this quite well I think because he doesn't feel badly. He just has a

few annoying symptoms right now.

Glad you were led to this group. Read the sister website. It has so

much info!!! There are a lot of amazing people here that will make

you feel right at home and answer any questions you may have!

Take Care

Kristi ~ Mom of Blade 11yo

> Hi everyone, I was wondering if anyone knew if IGA Neph. is

> inherited or Could I possible pass it on to my Child or future

> children ?

>

> Also I have been diagn with Kidney disiese for over 6 yr.s

> my latest Creatine was 2.0 last month with a blood test performed

by

> my Dr. What Stage is that considered Stage 3 ? if so what could

> possible be my current kidney Function ? 50% 60 70 ?? does anyone

> have a clue ?

>

> I may be going to get a biopsy soon to confirm my IGA diagnoses.

> My nephrologist suspects this after noticing red blood cells in my

> urine sample at my last visit a few days ago.

>

> I feel great most of the time, try to exercise ie a recumbent bike

&

> treadmill, along with light weights, stetches and sit-ups.

> and I have been eating less Sat fats less sodium and and more

lowfat

> veget. types of food. I still could do better but I'm excited about

> losing some weight and feeling better & looking better.

>

> I must also add that my mother died when I was a year and 1/2 years

> old of Lupus, the dr. seems to think that I probably do not have

> that since males tend to have it rarely passed to them ? any

> feedback on this would be appreciated.

>

> I hope I did not seem tooo long winded. I am from Texas

> home of Texas ATM University is anyone ever been around these parts

> I'm 38 and have been here my whole life, I have been married

> since '92 and we have a son who's 6 going into the first grade,

he's

> a card and such a blessing, speaking of blessings are there any

> belivers in the Lord out there ? write me if you can, I have so

many

> emotional ups and downs trying to make heads or tails of this

> Diseise.

[Guest guest]

Thank you Jeff

The stress of everyday life without a child with a kidney disease is bad

enough. I am still waiting for the feeling that some people speak about on

this list. “The new normal”. Haven’t found it yet, but still looking and

waiting.

God Bless

Cathy……Jennell’s Mom

_____

From: iga-nephropathy

[mailto:iga-nephropathy ] On Behalf Of Jeff Shrimpton

Sent: Thursday, August 11, 2005 10:06 AM

To: iga-nephropathy

Subject: RE: INHERITED? AGGIE, LETS Talk

Hi Cathy, I hope your ok, I can't imagine the stress you must go thru, when

its your child.

talk to you later

Cathy Waelty cwaelty@...> wrote:

Hi meandyou,

I am a strong believer in the Lord. Without him I don’t know what I would

do. Although I do have weak days whereas turning to him is sometimes hard (

I went through the question “why my daughter” and laws very mad at that time

) but thankfully I find him again. My daughter is 16 ½ yrs old and was

diagnosed with Igan and HSP last February.

God Bless

Cathy……Jennell’s Mom

_____

_____

[Guest guest]

your welcome, God Bless you to

Cathy Waelty cwaelty@...> wrote:Thank you Jeff

The stress of everyday life without a child with a kidney disease is bad

enough. I am still waiting for the feeling that some people speak about on

this list. “The new normal”. Haven’t found it yet, but still looking and

waiting.

God Bless

Cathy……Jennell’s Mom

_____

From: iga-nephropathy

[mailto:iga-nephropathy ] On Behalf Of Jeff Shrimpton

Sent: Thursday, August 11, 2005 10:06 AM

To: iga-nephropathy

Subject: RE: INHERITED? AGGIE, LETS Talk

Hi Cathy, I hope your ok, I can't imagine the stress you must go thru, when

its your child.

talk to you later

Cathy Waelty cwaelty@...> wrote:

Hi meandyou,

I am a strong believer in the Lord. Without him I don’t know what I would

do. Although I do have weak days whereas turning to him is sometimes hard (

I went through the question “why my daughter” and laws very mad at that time

) but thankfully I find him again. My daughter is 16 ½ yrs old and was

diagnosed with Igan and HSP last February.

God Bless

Cathy……Jennell’s Mom

_____

_____