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For those of you who are more understanding of lab stuff...on my

flowsheet from the Nephrologist office, there is a section that

says 'Renal' with 3 tests under it...Urea, Cr, UP.

Are these tests from blood or the 24-hr urine?

Also, under the UP heading are 2 numbers written like a

fraction...ie: 0.33/9.3...any idea what these numbers mean and their

unit value?

Thanks,

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Hi ,

Urea is the same thing as BUN (blood urea nitrogen). This is a waste

product from produced by the body (just like creatinine) from muscle

activity, chemical reactions, etc. Like creatinine, this becomes elevated

if the kidneys are not working properly. This is from the blood specimen.

Cr is creatinine. This is also from the blood specimen.

I am not sure about UP (best guess is urine protein - but that is a GUESS).

CY

Renal testing

> For those of you who are more understanding of lab stuff...on my

> flowsheet from the Nephrologist office, there is a section that

> says 'Renal' with 3 tests under it...Urea, Cr, UP.

>

> Are these tests from blood or the 24-hr urine?

>

> Also, under the UP heading are 2 numbers written like a

> fraction...ie: 0.33/9.3...any idea what these numbers mean and their

> unit value?

>

> Thanks,

>

>

>

>

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

>

> To unsubcribe via email,

> iga-nephropathy-unsubscribe

> Visit our companion website at www.igan.ca. The site is entirely supported

> by donations. If you would like to help, go to:

> http://www.igan.ca/id62.htm

>

> Thank you

>

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Thanks Cy...I am assuming the same thing as you mentioned but I wanted to

clarify that I wasn't missing something for things found via the blood and

urine.

Now I just have to figure out if the " UP " means urine protein than what the 2

different numbers are.

Oh...and one other question...alb is albumin found in blood...so would this 'UP'

be the proteinuria found in urine, if infact 'UP' stands for urine protein?

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Hi ,

Albumin is a very small protein. Because it is so small, it is the first to

leak into the urine when there is very, very mild kidney damage. It is

measured in blood to get an idea of nutritional intake, and it is measured

in urine to track the potential for diabetic nephropathy in diabetics. The

one in blood in regularly checked in IgAN and ESRD patients, but there is no

basis to know what purpose measuring albumin in urine serves in anyone but

people who have diabetes. Still, sometimes it's there in the lab results

anyway.

Pierre

Re: Renal testing

> Thanks Cy...I am assuming the same thing as you mentioned but I wanted to

> clarify that I wasn't missing something for things found via the blood and

> urine.

>

> Now I just have to figure out if the " UP " means urine protein than what

> the 2 different numbers are.

>

> Oh...and one other question...alb is albumin found in blood...so would

> this 'UP' be the proteinuria found in urine, if infact 'UP' stands for

> urine protein?

>

>

>

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Albumen isn't necessarily tested in just serum - frequently docs measure

microalbumen in urine as well.

If is stands for urine protein, it refers to protein in the urine. As you

surmised, this is what we refer to as " proteinuria " when the values are

abnormal. I wouldn't read too much into this value because a spot test for

urine protein is pretty meaningless by itself. It's affected by many

factors such as hydration, time of day, etc. That is why doing a protein

creatinine ratio (or an albumen creatinine ratio) or a 24 hour specimen is

neccessary.

Cy

Re: Renal testing

> Thanks Cy...I am assuming the same thing as you mentioned but I wanted to

> clarify that I wasn't missing something for things found via the blood and

> urine.

>

> Now I just have to figure out if the " UP " means urine protein than what

> the 2 different numbers are.

>

> Oh...and one other question...alb is albumin found in blood...so would

> this 'UP' be the proteinuria found in urine, if infact 'UP' stands for

> urine protein?

>

>

>

>

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My values are based upon a 24-hr urine.

Is there a formula for doing a serum creatinine to a urine protein ratio?

....maybe this is the bottom number under my urine protein values...maybe my

doctor has already done it.

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There is no such thing as a serum creatinine to urine protein ratio. You

can calculate a protein/creatinine ratio by dividing urine protein by urine

creatinine. This is only done with spot samples. It's worth checking that

your units match.

I assumed that the creatinine you referred to was serum creatinine because

it appeared next to BUN (typical lab sheets report serum creatinine next to

BUN). If you want to double check on this however, a normal creatinine for

a kid is somewhere around 0.5 ish. What values did the lab sheet indeicate?

Cy

Re: Renal testing

> My values are based upon a 24-hr urine.

>

> Is there a formula for doing a serum creatinine to a urine protein ratio?

> ...maybe this is the bottom number under my urine protein values...maybe

> my doctor has already done it.

>

>

>

>

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Cy:

I'm not familiar with everyone on this website yet so please tell me how you fit

into IgAN? You seem to know a whole bunch of information.

Okay on the ratio question. I wasn't reading results from a typical lab

printout...it's off a flowsheet from the Nephrologist that he uses so there are

no test names or units in which the value is recorded at. If I was allowed my

results directly how they come from the lab I wouldn't have so many questions as

to what my results mean because it would all be there in black and white for me.

I am trying to find out what numbers on this flowsheet are important to look at

as far as knowing how IgAN is progressing in me. I would have asked my

Nephrologist if I had been given my results at the time of my appointment but

they were mailed to me a week later on this flowsheet which means jack to

someone who isn't in the medical field.

Under the flowsheets heading of 'Haematology' he tests my Hb, WBC and Plt. I

know what all those are, their values and ranges. Then under the heading

'Renal' there is Urea, Cr and UP. I am trying to figure out what these 3 things

are, what their values are and 2 of the 3 of them I've found the normal ranges

on.

Under the 'UP' column he has written in two numbers each time my blood/ 24-hr

urine has been tested. The top number is always a decimal number, then there is

a line and then another decimal number. It looks like how a fraction is

written. The top number is always 0.XX and the bottom number is always higher

than 7.XX.

Also, when doctors or internet sources say to have a certain something checked

regularly, do you know if there is a certain timeframe that 'regularly' refers

to? I've noticed that although I'm on a statin, my doctor has failed to test my

liver...isn't that something that should be 'regularly' done? Like atleast once

a year or more?

Thanks for your help,

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Hi ,

I'm not sure what your doc was getting at in that UP column. I can

certainly see why you thought it might be a protein creatinine ratio, but

this is not commonly expressed as a fraction. Why don't you give your

neph's office a call and ask?

As you surmised, " regularly " can mean many things. My son used to do

regular labs every two weeks - which changed to regular labs every month -

which changed to regular labs every two months. Checking for liver damage

involves assaying for alkaline phosphatase. This test is common to many

different chem panels - so it may have been done without you knowing about

it (I'm not saying it was - I'm just saying it might have been).

I am a moderator on this site. My 14 year old son has MPGN - a renal

disease that is similar to IgAN in many respects only more extreme

Unfortunately, there are no email lists or Yahoo groups for MPGN - given

the rarity of MPGN, those would be very short lists indeed! Many years ago,

I used to do medical research. Presently, I'm more involved in scientific

policy issues.

Cy

Re: Renal testing

> Cy:

>

> I'm not familiar with everyone on this website yet so please tell me how

> you fit into IgAN? You seem to know a whole bunch of information.

>

> Okay on the ratio question. I wasn't reading results from a typical lab

> printout...it's off a flowsheet from the Nephrologist that he uses so

> there are no test names or units in which the value is recorded at. If I

> was allowed my results directly how they come from the lab I wouldn't have

> so many questions as to what my results mean because it would all be there

> in black and white for me.

>

> I am trying to find out what numbers on this flowsheet are important to

> look at as far as knowing how IgAN is progressing in me. I would have

> asked my Nephrologist if I had been given my results at the time of my

> appointment but they were mailed to me a week later on this flowsheet

> which means jack to someone who isn't in the medical field.

>

> Under the flowsheets heading of 'Haematology' he tests my Hb, WBC and Plt.

> I know what all those are, their values and ranges. Then under the

> heading 'Renal' there is Urea, Cr and UP. I am trying to figure out what

> these 3 things are, what their values are and 2 of the 3 of them I've

> found the normal ranges on.

>

> Under the 'UP' column he has written in two numbers each time my blood/

> 24-hr urine has been tested. The top number is always a decimal number,

> then there is a line and then another decimal number. It looks like how a

> fraction is written. The top number is always 0.XX and the bottom number

> is always higher than 7.XX.

>

> Also, when doctors or internet sources say to have a certain something

> checked regularly, do you know if there is a certain timeframe that

> 'regularly' refers to? I've noticed that although I'm on a statin, my

> doctor has failed to test my liver...isn't that something that should be

> 'regularly' done? Like atleast once a year or more?

>

> Thanks for your help,

>

>

>

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