my husband discovered he has PSC

[Guest guest]

Hello,

My name is Sally, and I am from Israel.

My husband, Amos, is 31 years old and we discovered he

has PSC almost 2 years ago.

He is taking pills on a daily basis 7x ursolit 300 mg'

and 3x metrogyl 250 mg'.

lately we found out that there is no blood flow in the

portal vein inside the liver. we are worried and

should see the doctor next week.

did anyone had this problem before? and how can it be

solved?

We would appreciate all information you have.

best wishes,

Sally

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[Guest guest]

Hi Sally;

Welcome to the group. I'm very sorry to hear about your husband's PSC

and portal vein blood flow problems. It is possible that your

husband's sclerosing cholangitis could be caused by an obstruction of

the portal vein, as described in this article:

Sclerosing Cholangitis: A Focus On Secondary Causes

Rupert Abdalian and E. Heathcote

HEPATOLOGY 2006; 44:1063-1074.

http://usagiedu.com/articles/ssc/ssc.pdf

(look under the section called " portal biliopathy " )

If your husband does not have inflammatory bowel disease (most PSC

patients do have ulcerative colitis, Crohn's or indeterminate

colitis) then this might be another reason for suspecting

a " secondary " cause of your husband's sclerosing cholangitis. This

would certainly be something to bring up with your husband's doctor

next week.

I hope that the portal vein obstruction can be resolved. IF this is

the cause of your husbands's sclerosing cholangitis, then you should

be encouraged that overcoming the portal vein obstruction may lead

to " partial or complete regression of bile duct abnormalities " , as

described in the article above.

Best regards,

Dave

(father of (22); PSC 07/03; UC 08/03)