ACEI Raising Creatinine and Other ?s

[Guest guest]

Hi all,

I just had my 6 month checkup with my neph. Everything was pretty

much in line with my last labs. My hematuria was 10-20 RBCs/HPF and

no proteinuria on the dipstick test. My creatinine did inch up from

1.1 to 1.2 which I know is still not that bad. However, I was put on

20mg of Lisinopril since the last time I had labwork done and I've

started working out with weights again in the last few weeks. It

didn't cross my mind to ask if either the Lisinopril and/or the

weightlifting could cause an increase. I thought I remember reading

somewhere (maybe on this board) that an ACE Inhibitor can artificially

raise your creatinine a bit. Is this true?

Also, my albumin/creatine ratio (I think that's what it was) was a bit

high (32.4 where < 20 is normal). That was the first time this area

was flagged on the report. Is this of much significance?

thanks!

Jack

[Guest guest]

Yes, when you start on or increase the dose of an ACE inhibitor, it's almost

expected that serum creatinine will go up a bit. If it goes up a lot, the

drug may have to be discontinued, but moderate increases are not

significant, since it's not a real decline in kidney function, just a

reflection that the drug is working (less blood pressure through the

glomeruli, less apparent kidney function). This is NOT the same as when a

drug actually causes acute renal failure.

Pierre

ACEI Raising Creatinine and Other ?s

> Hi all,

>

> I just had my 6 month checkup with my neph. Everything was pretty

> much in line with my last labs. My hematuria was 10-20 RBCs/HPF and

> no proteinuria on the dipstick test. My creatinine did inch up from

> 1.1 to 1.2 which I know is still not that bad. However, I was put on

> 20mg of Lisinopril since the last time I had labwork done and I've

> started working out with weights again in the last few weeks. It

> didn't cross my mind to ask if either the Lisinopril and/or the

> weightlifting could cause an increase. I thought I remember reading

> somewhere (maybe on this board) that an ACE Inhibitor can artificially

> raise your creatinine a bit. Is this true?

>

> Also, my albumin/creatine ratio (I think that's what it was) was a bit

> high (32.4 where < 20 is normal). That was the first time this area

> was flagged on the report. Is this of much significance?

>

> thanks!

>

> Jack

>

[Guest guest]

Hi Jack,

The fact that your creatinine went from 1.1 to 1.2 is probably not

significant and in fact is in the normal range for a male. That coupled with

the fact

that you have no protein are both great indicators. The Lisinopril could

have caused that slight increase, and it could also be that you were a bit more

dehydrated with this blood draw.

Overall, it looks like good news.

In a message dated 6/30/2005 8:22:52 A.M. Pacific Daylight Time,

tettnanger7@... writes:

Hi all,

I just had my 6 month checkup with my neph. Everything was pretty

much in line with my last labs. My hematuria was 10-20 RBCs/HPF and

no proteinuria on the dipstick test. My creatinine did inch up from

1.1 to 1.2 which I know is still not that bad. However, I was put on

20mg of Lisinopril since the last time I had labwork done and I've

started working out with weights again in the last few weeks. It

didn't cross my mind to ask if either the Lisinopril and/or the

weightlifting could cause an increase. I thought I remember reading

somewhere (maybe on this board) that an ACE Inhibitor can artificially

raise your creatinine a bit. Is this true?

Also, my albumin/creatine ratio (I think that's what it was) was a bit

high (32.4 where < 20 is normal). That was the first time this area

was flagged on the report. Is this of much significance?

thanks!

Jack

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