Re: Re: Topper blood pressure higher when upright

[Guest guest]

http://www.ndrf.org/orthostat.htm

sue

The normal response for a change in body position, results in a stabilization to the upright position in approximately sixty seconds. During this process, the normal change in heart rate would include an increase in heart rate of 10 to 15 beats per minute, and an increase in diastolic pressure of 10 mm Hg, with only a slight change in systolic pressure.

For those who are afflicted with Orthostatic Intolerance, there is an excessive increase in heart rate upon standing, resulting in the cardiovascular system working harder to maintain blood pressure and blood flow to the brain.

Upright posture also brings about a neurohumoral response, involving a change in the levels of vasopressin, renin, angiotensin and aldosterone levels - all of which are involved in the regulation of blood pressure.

Additionally, arterial baroreceptors, particularly those in the carotid sinus area, play an important role in the regulation of blood pressure and the response to positional changes. As the heart pumps blood to the body, the left atrium is passively filled with blood as a result of the force exerted by venous blood pressure. The baroreceptors in the left atrium respond, proportionately, to the pressure exerted by this venous blood pressure. Thus, a drop in venous blood pressure will trigger a compensatory response to increase blood pressure.

Any disruption in any of these processes, or their coordination, can result in an inappropriate response to an upright position, and can lead to a series of symptoms, and may include syncope.

Let me sleep on this.... In the mean time...

Can anyone else think of what can cause BP and/or pulse to drop reclining

and be more normal when upright???

How long have you been taking the GABA? I just looked it up

http://en.wikipedia.org/wiki/GABA it mentions affecting

neurotransmitters, sections of the brand and gland function.. but doesn't

specify what glands.

I wonder if it's a variable?? Do the docs know you are taking it?

The part where it says it's affecting receptors in the brain... makes me

want to understand it better.

It does seem that it would be affecting adrenal surge, I THINK, if you

are surging later at night... but you'd need tests to see....

I guess I need to know how long you've been taking it... and what dose(S)

for that period of time....

Topper ()

..

[Guest guest]

http://www.ndrf.org/orthostat.htm

sue

The normal response for a change in body position, results in a stabilization to the upright position in approximately sixty seconds. During this process, the normal change in heart rate would include an increase in heart rate of 10 to 15 beats per minute, and an increase in diastolic pressure of 10 mm Hg, with only a slight change in systolic pressure.

For those who are afflicted with Orthostatic Intolerance, there is an excessive increase in heart rate upon standing, resulting in the cardiovascular system working harder to maintain blood pressure and blood flow to the brain.

Upright posture also brings about a neurohumoral response, involving a change in the levels of vasopressin, renin, angiotensin and aldosterone levels - all of which are involved in the regulation of blood pressure.

Additionally, arterial baroreceptors, particularly those in the carotid sinus area, play an important role in the regulation of blood pressure and the response to positional changes. As the heart pumps blood to the body, the left atrium is passively filled with blood as a result of the force exerted by venous blood pressure. The baroreceptors in the left atrium respond, proportionately, to the pressure exerted by this venous blood pressure. Thus, a drop in venous blood pressure will trigger a compensatory response to increase blood pressure.

Any disruption in any of these processes, or their coordination, can result in an inappropriate response to an upright position, and can lead to a series of symptoms, and may include syncope.

Let me sleep on this.... In the mean time...

Can anyone else think of what can cause BP and/or pulse to drop reclining

and be more normal when upright???

How long have you been taking the GABA? I just looked it up

http://en.wikipedia.org/wiki/GABA it mentions affecting

neurotransmitters, sections of the brand and gland function.. but doesn't

specify what glands.

I wonder if it's a variable?? Do the docs know you are taking it?

The part where it says it's affecting receptors in the brain... makes me

want to understand it better.

It does seem that it would be affecting adrenal surge, I THINK, if you

are surging later at night... but you'd need tests to see....

I guess I need to know how long you've been taking it... and what dose(S)

for that period of time....

Topper ()

..

[Guest guest]

http://www.ndrf.org/orthostat.htm

sue

The normal response for a change in body position, results in a stabilization to the upright position in approximately sixty seconds. During this process, the normal change in heart rate would include an increase in heart rate of 10 to 15 beats per minute, and an increase in diastolic pressure of 10 mm Hg, with only a slight change in systolic pressure.

For those who are afflicted with Orthostatic Intolerance, there is an excessive increase in heart rate upon standing, resulting in the cardiovascular system working harder to maintain blood pressure and blood flow to the brain.

Upright posture also brings about a neurohumoral response, involving a change in the levels of vasopressin, renin, angiotensin and aldosterone levels - all of which are involved in the regulation of blood pressure.

Additionally, arterial baroreceptors, particularly those in the carotid sinus area, play an important role in the regulation of blood pressure and the response to positional changes. As the heart pumps blood to the body, the left atrium is passively filled with blood as a result of the force exerted by venous blood pressure. The baroreceptors in the left atrium respond, proportionately, to the pressure exerted by this venous blood pressure. Thus, a drop in venous blood pressure will trigger a compensatory response to increase blood pressure.

Any disruption in any of these processes, or their coordination, can result in an inappropriate response to an upright position, and can lead to a series of symptoms, and may include syncope.

Let me sleep on this.... In the mean time...

Can anyone else think of what can cause BP and/or pulse to drop reclining

and be more normal when upright???

How long have you been taking the GABA? I just looked it up

http://en.wikipedia.org/wiki/GABA it mentions affecting

neurotransmitters, sections of the brand and gland function.. but doesn't

specify what glands.

I wonder if it's a variable?? Do the docs know you are taking it?

The part where it says it's affecting receptors in the brain... makes me

want to understand it better.

It does seem that it would be affecting adrenal surge, I THINK, if you

are surging later at night... but you'd need tests to see....

I guess I need to know how long you've been taking it... and what dose(S)

for that period of time....

Topper ()

..

[Guest guest]

http://www.ndrf.org/orthostat.htm

sue

The normal response for a change in body position, results in a stabilization to the upright position in approximately sixty seconds. During this process, the normal change in heart rate would include an increase in heart rate of 10 to 15 beats per minute, and an increase in diastolic pressure of 10 mm Hg, with only a slight change in systolic pressure.

For those who are afflicted with Orthostatic Intolerance, there is an excessive increase in heart rate upon standing, resulting in the cardiovascular system working harder to maintain blood pressure and blood flow to the brain.

Upright posture also brings about a neurohumoral response, involving a change in the levels of vasopressin, renin, angiotensin and aldosterone levels - all of which are involved in the regulation of blood pressure.

Additionally, arterial baroreceptors, particularly those in the carotid sinus area, play an important role in the regulation of blood pressure and the response to positional changes. As the heart pumps blood to the body, the left atrium is passively filled with blood as a result of the force exerted by venous blood pressure. The baroreceptors in the left atrium respond, proportionately, to the pressure exerted by this venous blood pressure. Thus, a drop in venous blood pressure will trigger a compensatory response to increase blood pressure.

Any disruption in any of these processes, or their coordination, can result in an inappropriate response to an upright position, and can lead to a series of symptoms, and may include syncope.

Let me sleep on this.... In the mean time...

Can anyone else think of what can cause BP and/or pulse to drop reclining

and be more normal when upright???

How long have you been taking the GABA? I just looked it up

http://en.wikipedia.org/wiki/GABA it mentions affecting

neurotransmitters, sections of the brand and gland function.. but doesn't

specify what glands.

I wonder if it's a variable?? Do the docs know you are taking it?

The part where it says it's affecting receptors in the brain... makes me

want to understand it better.

It does seem that it would be affecting adrenal surge, I THINK, if you

are surging later at night... but you'd need tests to see....

I guess I need to know how long you've been taking it... and what dose(S)

for that period of time....

Topper ()

..