Guest guest Posted May 2, 2007 Report Share Posted May 2, 2007 I read this on the website www.altsupportthyroid.org " Hypothyroid patients are usually unable to convert inactive T4 into acitve T3, owing to a lack of 5'-deiodinase in liver and kidneys. " My assumption is that this results in a normal or low TSH becasue the pituitary senses enough T4. Is that correct? What happens to the T4 if it's not being converted? I'm trying to learn as much as I can. Please forgive me if this has already been asked and answered. Thanks, Lori Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2007 Report Share Posted May 2, 2007 > > I read this on the website www.altsupportthyroid.org > > " Hypothyroid patients are usually unable to convert inactive T4 into > acitve T3, owing to a lack of 5'-deiodinase in liver and kidneys. " > > My assumption is that this results in a normal or low TSH becasue the > pituitary senses enough T4. Is that correct? > > What happens to the T4 if it's not being converted? > > I'm trying to learn as much as I can. Please forgive me if this has > already been asked and answered. > > Thanks, Lori > 80% of all hypo patients have no conversion issues. For the other 20% the above statement is one of many possibilities..most T4 is converted to T3 in the liver..but 95% of all T4 is bound and most T3 is also bound. Blanket statements like above ( meaning all) hypo..have this problem is misleading. The thyroid produces TBG..this is thyroid binding globin.. it can be effected by medications, estrogen levels, genetics etc. An easy way to tell if you are converting or not converting is to have the doc run T4 and T3 in the free versions..if your T3 is low but you T4 is at the high end of the range then you know you have conversion issues.. Some older essays that we do not like to see the dcos run are actually useful in cases of conversion issues..things like Total T4 and Reverse T3 will let you know if all the T4 is bound or if most of it is free but the body is converting to reverse T3 instead? TBG can also be tested. Kats3boys Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2007 Report Share Posted May 2, 2007 Thank you for your response. My T3 is 2.9 range 2.3-4.2 T4 1.23 range .61-1.76 TSH .11 range .35-5.5 These are from a blood test done in March. I'm waiting on my Armour to get here to help boost my T3's. I'm currently on Levoxyl and think I might need to keep a little of that with the Armour. We'll see how I feel. Lori Re: Am I on the right track? >> I read this on the website www.altsupportthyroid.org > > "Hypothyroid patients are usually unable to convert inactive T4 into > acitve T3, owing to a lack of 5'-deiodinase in liver and kidneys."> > My assumption is that this results in a normal or low TSH becasue the > pituitary senses enough T4. Is that correct?> > What happens to the T4 if it's not being converted?> > I'm trying to learn as much as I can. Please forgive me if this has > already been asked and answered.> > Thanks, Lori>80% of all hypo patients have no conversion issues. For the other 20% the above statement is one of many possibilities..most T4 is converted to T3 in the liver..but 95% of all T4 is bound and most T3 is also bound.Blanket statements like above ( meaning all) hypo..have this problem is misleading.The thyroid produces TBG..this is thyroid binding globin.. it can be effected by medications, estrogen levels, genetics etc.An easy way to tell if you are converting or not converting is to have the doc run T4 and T3 in the free versions..if your T3 is low but you T4 is at the high end of the range then you know you have conversion issues..Some older essays that we do not like to see the dcos run are actually useful in cases of conversion issues..things like Total T4 and Reverse T3 will let you know if all the T4 is bound or if most of it is free but the body is converting to reverse T3 instead?TBG can also be tested.Kats3boys Quote Link to comment Share on other sites More sharing options...
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