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>

> Hello, My name is Tonja, I am 27 years old and found out I have

> hyperthyrodism back in 2002. Since then I have been treated with the

> radioactive pill twice and no longer have the gotier. But I recently

> had my levels checked and was advised that my thyriod levels are

> suppressed. I have no idea what that means. I do not that I get no

slee

> but always fill drained. My muscles are always aching. I feel like my

> body is going through more changes. Is there someone who can answer

my

> questions.

>

> God bless

>

The antibody responsible for Grave's disease can cause you to have a

suppressed TSH regardless of thyroid function. It is very important

that you get monitored.

This report is from Pubmed..

PURPOSE: To characterize the time course of recovery of the

hypothalamic-pituitary-thyroid (HPT) axis by determining the

frequency, onset, duration, and clinical attributes of the central

hypothyroid phase following 131I therapy for Graves' disease and to

examine whether the central hypothyroid phase is due to direct

pituitary thyrotroph suppression or to hypothalamic thyrotropin-

releasing hormone (TRH) deficiency. PATIENTS AND METHODS: Twenty-one

hyperthyroid patients with Graves' disease evaluated at a university

endocrine clinic and treated with radioactive iodine were

prospectively studied. Serial thyroid function levels (serum

thyroxine [T4], free thyroxine [free T4], triiodothyronine [T3], and

thyroid-stimulating hormone [TSH]) were measured and TRH stimulation

tests were performed at 2 to 4 week intervals for all subjects

following 131I treatment. None of the patients was treated with

thionamides after receiving 131I therapy. RESULTS: Nineteen (90%) of

the patients with Graves' disease experienced a transient central

hypothyroid phase defined as the presence of a suppressed or

inappropriately normal TSH level despite a low free T4 level

following 131I treatment. This phase occurred a mean of 62.8 +/- 5.1

days following 131I treatment, persisted for an average of 24.7 +/-

2.4 days, and was not predictive of eventual treatment outcome. All

patients had concordantly low T4 and T3 levels during this period and

exhibited a blunted TSH response to TRH compared to 29 euthyroid

control subjects, suggesting primary feedback suppression at the

level of the pituitary thyrotrophs. The suppressed thyrotrophs

required a minimum of 2 weeks to recover once patients became

hypothyroid. The length of preexisting hyperthyroidism, basal free T4

elevation, and administered dose of 131I failed to predict the

duration of the central hypothyroid phase, although a higher dose of

131I was associated with an earlier onset of central hypothyroidism

(r = -.51, P < 0.05). CONCLUSIONS: Clinicians should be aware of the

delay in the recovery of the HPT axis that occurs in the majority of

patients with Graves' disease treated with 131I and is manifested by

a transient central hypothyroid phase. The blunted TSH response to

TRH stimulation during this period suggests that suppression occurs

primarily at the level of the pituitary thyrotrophs. The use of

sensitive TSH measurements alone to monitor these patients during

this period is not helpful and may be misleading.

With your symptoms that you listed and being POST RAI..my guess is that

although the TSH is suppressed you are hypothyroid. The way to check

this is to have your T4 and T3 tested although make sure they are

tested in the free form so FT4 and FT3.

Kats3boys

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Do you have copies of your labs for us to see?

If they are saying your levels are suppressed they are referring to your

TSH level... that's good... suppression of the gland activity is a good

thing, it minimizes risk of recurrence... but your symptoms are

suggesting that your thyroid hormone levels are still too low... that's

not a good thing... you need a balance... enough replacment hormone to

keep your TSH level down while bring your thyroid hormones up high enough

to allow your body to function in a healthy manner without getting high

enough to cause you to become hyper.

Some questions....

What med are you on now?

How much?

For how long?

When was your last blood test?

When was your last dosage adjustment?

Did they ever tell you what caused you to be hyperthyroid?

Did they treat you with anything before giving you the radiation?

Topper ()

On Thu, 19 Apr 2007 20:12:51 -0000 " stonja19 " stonja19@...>

writes:

> Hello, My name is Tonja, I am 27 years old and found out I have

> hyperthyrodism back in 2002. Since then I have been treated with the

> radioactive pill twice and no longer have the gotier. But I recently

> had my levels checked and was advised that my thyriod levels are

> suppressed. I have no idea what that means. I do not that I get no

> slee

> but always fill drained. My muscles are always aching. I feel like

> my

> body is going through more changes. Is there someone who can answer

> my

> questions.

>

> God bless

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Good Morning,

What med are you on now? Methamoizle

How much? 10mg

For how long? 8 months

When was your last blood test? March 16

When was your last dosage adjustment? March 19 I was taking to pills a

day and the docotors changed it to back to one pill a day.

Did they ever tell you what caused you to be hyperthyroid? NO cause

Did they treat you with anything before giving you the radiation?

I was on sythroid for about a year before the methzmoizle

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>

> Good Morning,

>

> What med are you on now? Methamoizle

> How much? 10mg

> For how long? 8 months

> When was your last blood test? March 16

> When was your last dosage adjustment? March 19 I was taking to

pills a

> day and the docotors changed it to back to one pill a day.

> Did they ever tell you what caused you to be hyperthyroid? NO cause

> Did they treat you with anything before giving you the radiation?

> I was on sythroid for about a year before the methzmoizle

>

You are using tapazole to treat hyper 2 years after RAI?

Do you have your labs from March?

Altough the doc said once a day, the manufactuer reccomends 3 times a

day although at lower doses you can go twice a day..

Now at 2 pills a day do you mena 2-10mg pills or 2-5 mg pills?

Sorry things are a little confusing here.

Kats3boys

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