Guest guest Posted January 7, 2006 Report Share Posted January 7, 2006 Hi, Just ordered my sons Td Ldn... it should get to me by wed or thursday... will keep you posted if we see any major gains in a ffew weeks...Initially many kids have sleep issues.. wake early, or get sick... bpody finally recognises an underlying virus & is dealing with it & then come the improvements In speech & social domains.... & eye contact & sensory issues too I've read. Hopeful. Xena > > Reports such as these need to be reviewed with cation. This is a " drug " with > potential side effects, and really has NOT been well studied in children. > Benign treatments (like fish oil- which we should be getting more of anyway > through a healthy diet that rarely exists in the typical US household these > days) really have no downside (but I read everything I could on it to make > sure - as even " benign supplements " can sometimes have serious adverse > effects). But when you are talking about using new and unproven drugs on > children, one needs to really proceed with caution - and should be > investigated as part of a clinical study. Not all liver toxicity is > reversible. A study of 15 children with autism does not insure that child > number 20 won't suffer from serious liver damage or something else > unexpected. Sounds like it is still too early in the game to know its safe > and effective. Think of the tens of thousands of patients who used vioxx > before Merck pulled it from the market. It will often take years before true > adverse events are realized. Another example...a new non-steroidal eczema > cream increases the risk of malignant skin cancer in children - a side > effect not known until post marketing experience. Yet everyone was so > excited to use a " non-steroidal " cream for this typically benign but very > annoying condition. One cannot compare living with eczema vs. skin cancer - > and most would not have risked it for their child had they known. Can blame > the drug company either - as they didn't know originally. The cure must not > be more dangerous than the condition it is treating. > > This may or may not turn out to be an exciting new treatment. But it is not > without risk. - > > The below info was not in children...but rather from older alcoholic > individuals. Its possible that this group was at increased risk due to > pre-existing liver damage...but no way to tell... > > ---------------------------------------------------------------------------- > ----------- > > What are the side effects of naltrexone? > > In the largest study, the most common side effect of naltrexone affected > only a small minority of people and included the following: nausea (10%), > headache (7%), dizziness (4%), fatigue (4%), insomnia (3%), anxiety (2%), > and sleepiness (2%). These side effects were usually mild and of short > duration. As treatment for alcoholism, naltrexone side effects, > predominantly nausea, have been se vere enough to discontinue the medication > in 5-10% of the patients starting it. For most other patients side effects > are mild or of brief duration. One serious possibility is that naltrexone > can have toxic effects on the liver. Blood tests of liver function are > performed prior to the onset of treatment and periodically during treatment > to determine whether naltrexone should be started and whether it should be > discontinued if the relatively rare side effect of liver toxicity is taking > place. > > 9. Do I need to get blood tests while I'm on naltrexone? How often? > > To ensure that naltrexone treatment is safe, blood tests should be obtained > prior to initial treatment. Following that, retesting generally occurs at > monthly intervals for the first three months, with less frequent testing > after that point. More frequent testing may be requested depending on the > health of your liver prior to beginning treatment. Blood tests are needed to > make sure that liver function is adequate prior to taking naltrexone and to > evaluate whether naltrexone is having adverse effects on the liver. > > > Quote Link to comment Share on other sites More sharing options...
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