Re: - Histame was: Challenging behavior- please offer suggestions!

[Guest guest]

Our ND in Boulder,CO, Steve Parcell (Naturemed), did a neurotransmitter profile

and found that Mia had extremely high excitatory neurotransmitters (the highest

by far that he had ever seen). This and her history (and later testing) revealed

lots of allergies, so with the high ex nt's and allergic response (and

neuropathy and other neurological issues), he recommended Xymogen's Histoxym.

http://www.xymogen.com/2008/formula.asp?code=000247

This had an immediate and significant effect. It calmed Mia a LOT, and she

stopped stumbling and falling down constantly. He explained that it is mainly an

enzyme that digests the excess histamine (and other ex nt's) so that it doesn't

cause vasoconstriction and hyperactivity. After a while I realized that Histame

has the same main ingredient- diamine oxidase derived from pork kidney- but that

I could get it much cheaper from Herbs Pro. We tried the Histame and it had the

same effect (although it doesn't have the Vit C and Calcium that the Histoxym

had).

Around the same time I was diving into the work of Dr. Theoharides and the

occurance of Mast Cell Activation Disorder and Mastocytosis in Autism. Mast

cells release Histamine and other neurotransmitters. IMHO, parasites cause mast

cells to degranulate and release their nt's. Anyway, the halmark of a person who

has significant mast cell activation issues is having a triad of symptoms- brain

(neurological disorder), bladder (pain, control problems, infections), gut

(digestion/absorption issues, diarrhea, constipation). Sounds like Autism to

me:)!

WOW, I am SO interested in hearing about the quercetin colds issue. I will think

on that- I wonder what the catalyst is? I know one thing about Quercetin is, in

the Mast Cell community, some people have very significant negative responses to

different brands because of the source of the Quercetin. I think the citrus

sources are an issue? Grapefruit? I don't remember exactly. We have had great

success with the Thorne brand, and whenever I try another one Mia goes off the

charts hyper/sensitive/crying. Recently I tried a brand that is derived from

Fava beans with the same bad effect. I will try it again in a few weeks, though,

because I don't know of course it if was just a bad day for another reason.

> > >

> > > Our son tries to smash his fingers into solid objects. The frequency

> is increasing as of late. Any ideas. We so appreciate any and all

> responses!

> > >

> > >

> > >

> > > --

> > > Toni

> > >

> > > ------

> > > Mind like a steel trap...

> > > Rusty and illegal in 37 states.

> > >

> >

>

[Guest guest]

We've also done neurotransmitter testing and my son is also very high in excitatory neurotransmitters, including histamine. We have done some of the Neuroscience supplements with some success. Interesting about the xymogen product...RuthOur ND in Boulder,CO, Steve Parcell (Naturemed), did a neurotransmitter profile and found that Mia had extremely high excitatory neurotransmitters (the highest by far that he had ever seen). This and her history (and later testing) revealed lots of allergies, so with the high ex nt's and allergic response (and neuropathy and other neurological issues), he recommended Xymogen's Histoxym.http://www.xymogen.com/2008/formula.asp?code=000247This had an immediate and significant effect. It calmed Mia a LOT, and she stopped stumbling and falling down constantly. He explained that it is mainly an enzyme that digests the excess histamine (and other ex nt's) so that it doesn't cause vasoconstriction and hyperactivity. After a while I realized that Histame has the same main ingredient- diamine oxidase derived from pork kidney- but that I could get it much cheaper from Herbs Pro. We tried the Histame and it had the same effect (although it doesn't have the Vit C and Calcium that the Histoxym had). Around the same time I was diving into the work of Dr. Theoharides and the occurance of Mast Cell Activation Disorder and Mastocytosis in Autism. Mast cells release Histamine and other neurotransmitters. IMHO, parasites cause mast cells to degranulate and release their nt's. Anyway, the halmark of a person who has significant mast cell activation issues is having a triad of symptoms- brain (neurological disorder), bladder (pain, control problems, infections), gut (digestion/absorption issues, diarrhea, constipation). Sounds like Autism to me:)!WOW, I am SO interested in hearing about the quercetin colds issue. I will think on that- I wonder what the catalyst is? I know one thing about Quercetin is, in the Mast Cell community, some people have very significant negative responses to different brands because of the source of the Quercetin. I think the citrus sources are an issue? Grapefruit? I don't remember exactly. We have had great success with the Thorne brand, and whenever I try another one Mia goes off the charts hyper/sensitive/crying. Recently I tried a brand that is derived from Fava beans with the same bad effect. I will try it again in a few weeks, though, because I don't know of course it if was just a bad day for another reason.> > >> > > Our son tries to smash his fingers into solid objects. The frequency> is increasing as of late. Any ideas. We so appreciate any and all> responses!> > > > > >> > >> > > --> > > Toni> > >> > > ------> > > Mind like a steel trap...> > > Rusty and illegal in 37 states.> > >> >>

[Guest guest]

Thanks , much appreciated!

When I first looked into histamine issues (actually only after starting

ketotifen, on friend's recommendation, and seeing great benefits with

it) I've been thinking about low DAO enzyme in autism (imo most likely

due to surpression by retro/viruses) and how nice it would be to have a

supplement degrading enzyme OT - had no idea it actually was available

already LOL. Having said that I'm a bit uneasy about it being derived

from animal tissue...

I've been asking around now since you posted, it looks like not many in

ASD biomed world are using Histame/Diosin or know about it (only one

reply, from someone who hasn't seen any effects). On CFS/ME and allergy

boards more people have tried taking it, with results ranging from

'fantastic' to no effects to negatives - interestingly enough one or two

reported more 'high-histamine' type effects with it...

Yes I agree, Theoharides rocks!

was the nt profile urine one? how reliable is that??

Natasa x

> > > >

> > > > Our son tries to smash his fingers into solid objects. The

frequency

> > is increasing as of late. Any ideas. We so appreciate any and all

> > responses!

> > > >

> > > >

> > > >

> > > > --

> > > > Toni

> > > >

> > > > ------

> > > > Mind like a steel trap...

> > > > Rusty and illegal in 37 states.

> > > >

> > >

> >

>

[Guest guest]

Wow, thanks for all of the information, thoughts, and leads. Yes, we finally

stopped Histame because I just wasn't comfortable with the source. Anything

derived from pork worries me. I need to see what our NT testing was. It was

almost 3 yrs ago, and I don't remember at the moment. Family is in town so I

won't be able to check into it for a few days.

Thanks again so much for sharing.

> > > > >

> > > > > Our son tries to smash his fingers into solid objects. The

> frequency

> > > is increasing as of late. Any ideas. We so appreciate any and all

> > > responses!

> > > > >

> > > > >

> > > > >

> > > > > --

> > > > > Toni

> > > > >

> > > > > ------

> > > > > Mind like a steel trap...

> > > > > Rusty and illegal in 37 states.

> > > > >

> > > >

> > >

> >

>