Re: Going for a blood test. When to take my meds??

[Guest guest]

Hi,

I've been reading your comments.. and have learned so much. Can you

tell me what FNA is all about? I do have hashi according to an

antibodies test they've done and I'm just curious if that shows just

an inflamation situation or would that be a true test for hashi's.

Also does FNA distinguish to the point of graves vs hashi's?

Thanks Connie

> >

> > Hi Kats,

> >

> > How did you get all your allergies diagnosed, particularly the

> food dye

> > ones?

> > I would love to have that done but don¹t have a clue where to

> start.

> > I live in Texas and tell doctors I have allergies and they

> prescribe Zyrtec

> > or Flonase and that¹s the end of it.

> >

> > What is PTU and what were you allergic to that you had to stop

> doing for the

> > test?

> >

> > How¹s your immune system and I wonder why you have so many

> allergies to so

> > many things in the environment..?

> > Were you sick often as a child or frail?

> >

> > Your labs look ³normal² to me and in good ranges but for the TPO

> which is

> > just about out of range and would point to Hashis, wouldn¹t it?

> >

> > Sue

> >

> I am healthy, never really sick as a child either, very

athletic..my

> allergies started in Grade 10 doing an experiment in chem class

that

> involved different heat sources and reactions to sulphur..put me

in

> the hospital for 4 days. For the other allergies it is a matter of

> keeping a food diary and yeah unfortunately I have been to the

> hospital more than once with an allergic reaction..other than

> allergies never sick unless it is a sinus infection from the

> allergies. But most of my allergies are digested so hives, swollen

> lips, swollen face..this is how they usually tell if it is

something

> you have eaten or something in the air..

>

> my allergist does what he calls challenge tests.. usually if I can

> suspect it he will then give me the substance starting off in

small

> increments and slowly increasing the amount to see if I have a

> reaction..

>

> My last one was to see if I was still allergic to codiene.. I was

> given 1mg every 15 mins for 2 doses and then 2 mgs every 15

> mins..til I hit 8 mgs..that was the end of it for me..hives.

>

> PTU is like Tapazole, an anti thyroid drug,it is meant to slow the

> production of the thyroid down..I was on a low dose just to try

and

> stop the flucuating. I was allergic to PTU did not have to stop it

> for a test but because even taking it with Benadryl my body

reacted

> to it.

>

> My labs are normal..My FT4 is at the top of the range, it swings

> back and forth between being at the top end and being just over.

> This is why I am playing the wait and see game.

>

> TPO is seen in both Hashi's and Grave's although with Hashi's it

is

> seen normally at a much higher number. TPO is an enxyme in the

> thyroid, during thyroid inflammation and also during the cell

> destruction seen in Hashi's TPO is released into the blood

stream..

> Being that TPO is not suppose to enter the blood stream the body

> reccognizes it as foriegn and produces antibodies against it. TPO

in

> sense is an inflammatory marker for the thyroid.

>

> This is from the Thyroid manager on FNA's and what my ENDO has

gone

> on..

> Benign Cytology

> Aspirates obtained from multinodular goiters, benign

microfollicular

> adenoma, or normal thyroid are referred to as " colloid nodules "

and

> show loosely cohesive sheaths of follicular epithelium, colloid,

> blood, and rare macrophages. Colloid nodules contain an abundance

of

> colloid with sparse follicular cells. There is considerable

> variation in the number of cells as well as the type and amount of

> colloid present.

>

> Another benign diagnosis is Hashimoto's thyroiditis; it has a

fairly

> characteristic pattern on FNA smears, showing hypercellularity

with

> lymphocytes, Hürthle cells, and minimal or no colloid

>

> This is what my Biopsy report says..

> follicular epithelium, colloid, blood, and rare macrophages.

>

> So no lympocytes or hurthle cells means no Hashi's and the thyroid

> is normal..

>

> Although a high TPO in the 100's or higher usually indicates

> Hashimoto's I know some on the Grave's board that have TPO's in

the

> 1000's, and any medical source that I find reliable with

scientific

> background have all said FNA is the only true test for Hashimoto's

> although up until a few years ago TPO was believed to be the test

> for it, now it is seen only as an inflammatory marker of the

thyroid.

>

> Kats3boys

>

[Guest guest]

Hi Kats,

My TPO is >1000 so I have hashis, hypo and goiter, no nodules.

On the allergies, that makes sense, if you swell or get hives, you are allergic.

So that would be different than an intolerance or sensitivity to, such as lactose, right?

I get bloated and gassy if I have even half a glass of milk for example.

Sometimes I have noticed though, that I get hives or my lips get itchy and “tight” and I always wondered what that was...am thinking now it’s a mild allergy so I will keep a look out for that.

Sounds like you have done a TON of research on this — you have an amazing amount of info!

Overall, what do you want to do as far as treatment? I know you are playing the waiting game, but why are you “swinging” so much with hyper to hypo? That has to feel pretty bad.

Sue

>

> Hi Kats,

>

> How did you get all your allergies diagnosed, particularly the

food dye

> ones?

> I would love to have that done but don’t have a clue where to

start.

> I live in Texas and tell doctors I have allergies and they

prescribe Zyrtec

> or Flonase and that’s the end of it.

>

> What is PTU and what were you allergic to that you had to stop

doing for the

> test?

>

> How’s your immune system and I wonder why you have so many

allergies to so

> many things in the environment..?

> Were you sick often as a child or frail?

>

> Your labs look “normal” to me and in good ranges but for the TPO

which is

> just about out of range and would point to Hashis, wouldn’t it?

>

> Sue

>

I am healthy, never really sick as a child either, very athletic..my

allergies started in Grade 10 doing an experiment in chem class that

involved different heat sources and reactions to sulphur..put me in

the hospital for 4 days. For the other allergies it is a matter of

keeping a food diary and yeah unfortunately I have been to the

hospital more than once with an allergic reaction..other than

allergies never sick unless it is a sinus infection from the

allergies. But most of my allergies are digested so hives, swollen

lips, swollen face..this is how they usually tell if it is something

you have eaten or something in the air..

my allergist does what he calls challenge tests.. usually if I can

suspect it he will then give me the substance starting off in small

increments and slowly increasing the amount to see if I have a

reaction..

My last one was to see if I was still allergic to codiene.. I was

given 1mg every 15 mins for 2 doses and then 2 mgs every 15

mins..til I hit 8 mgs..that was the end of it for me..hives.

PTU is like Tapazole, an anti thyroid drug,it is meant to slow the

production of the thyroid down..I was on a low dose just to try and

stop the flucuating. I was allergic to PTU did not have to stop it

for a test but because even taking it with Benadryl my body reacted

to it.

My labs are normal..My FT4 is at the top of the range, it swings

back and forth between being at the top end and being just over.

This is why I am playing the wait and see game.

TPO is seen in both Hashi's and Grave's although with Hashi's it is

seen normally at a much higher number. TPO is an enxyme in the

thyroid, during thyroid inflammation and also during the cell

destruction seen in Hashi's TPO is released into the blood stream..

Being that TPO is not suppose to enter the blood stream the body

reccognizes it as foriegn and produces antibodies against it. TPO in

sense is an inflammatory marker for the thyroid.

This is from the Thyroid manager on FNA's and what my ENDO has gone

on..

Benign Cytology

Aspirates obtained from multinodular goiters, benign microfollicular

adenoma, or normal thyroid are referred to as " colloid nodules " and

show loosely cohesive sheaths of follicular epithelium, colloid,

blood, and rare macrophages. Colloid nodules contain an abundance of

colloid with sparse follicular cells. There is considerable

variation in the number of cells as well as the type and amount of

colloid present.

Another benign diagnosis is Hashimoto's thyroiditis; it has a fairly

characteristic pattern on FNA smears, showing hypercellularity with

lymphocytes, Hürthle cells, and minimal or no colloid

This is what my Biopsy report says..

follicular epithelium, colloid, blood, and rare macrophages.

So no lympocytes or hurthle cells means no Hashi's and the thyroid

is normal..

Although a high TPO in the 100's or higher usually indicates

Hashimoto's I know some on the Grave's board that have TPO's in the

1000's, and any medical source that I find reliable with scientific

background have all said FNA is the only true test for Hashimoto's

although up until a few years ago TPO was believed to be the test

for it, now it is seen only as an inflammatory marker of the thyroid.

Kats3boys

[Guest guest]

Hi Kats,

My TPO is >1000 so I have hashis, hypo and goiter, no nodules.

On the allergies, that makes sense, if you swell or get hives, you are allergic.

So that would be different than an intolerance or sensitivity to, such as lactose, right?

I get bloated and gassy if I have even half a glass of milk for example.

Sometimes I have noticed though, that I get hives or my lips get itchy and “tight” and I always wondered what that was...am thinking now it’s a mild allergy so I will keep a look out for that.

Sounds like you have done a TON of research on this — you have an amazing amount of info!

Overall, what do you want to do as far as treatment? I know you are playing the waiting game, but why are you “swinging” so much with hyper to hypo? That has to feel pretty bad.

Sue

>

> Hi Kats,

>

> How did you get all your allergies diagnosed, particularly the

food dye

> ones?

> I would love to have that done but don’t have a clue where to

start.

> I live in Texas and tell doctors I have allergies and they

prescribe Zyrtec

> or Flonase and that’s the end of it.

>

> What is PTU and what were you allergic to that you had to stop

doing for the

> test?

>

> How’s your immune system and I wonder why you have so many

allergies to so

> many things in the environment..?

> Were you sick often as a child or frail?

>

> Your labs look “normal” to me and in good ranges but for the TPO

which is

> just about out of range and would point to Hashis, wouldn’t it?

>

> Sue

>

I am healthy, never really sick as a child either, very athletic..my

allergies started in Grade 10 doing an experiment in chem class that

involved different heat sources and reactions to sulphur..put me in

the hospital for 4 days. For the other allergies it is a matter of

keeping a food diary and yeah unfortunately I have been to the

hospital more than once with an allergic reaction..other than

allergies never sick unless it is a sinus infection from the

allergies. But most of my allergies are digested so hives, swollen

lips, swollen face..this is how they usually tell if it is something

you have eaten or something in the air..

my allergist does what he calls challenge tests.. usually if I can

suspect it he will then give me the substance starting off in small

increments and slowly increasing the amount to see if I have a

reaction..

My last one was to see if I was still allergic to codiene.. I was

given 1mg every 15 mins for 2 doses and then 2 mgs every 15

mins..til I hit 8 mgs..that was the end of it for me..hives.

PTU is like Tapazole, an anti thyroid drug,it is meant to slow the

production of the thyroid down..I was on a low dose just to try and

stop the flucuating. I was allergic to PTU did not have to stop it

for a test but because even taking it with Benadryl my body reacted

to it.

My labs are normal..My FT4 is at the top of the range, it swings

back and forth between being at the top end and being just over.

This is why I am playing the wait and see game.

TPO is seen in both Hashi's and Grave's although with Hashi's it is

seen normally at a much higher number. TPO is an enxyme in the

thyroid, during thyroid inflammation and also during the cell

destruction seen in Hashi's TPO is released into the blood stream..

Being that TPO is not suppose to enter the blood stream the body

reccognizes it as foriegn and produces antibodies against it. TPO in

sense is an inflammatory marker for the thyroid.

This is from the Thyroid manager on FNA's and what my ENDO has gone

on..

Benign Cytology

Aspirates obtained from multinodular goiters, benign microfollicular

adenoma, or normal thyroid are referred to as " colloid nodules " and

show loosely cohesive sheaths of follicular epithelium, colloid,

blood, and rare macrophages. Colloid nodules contain an abundance of

colloid with sparse follicular cells. There is considerable

variation in the number of cells as well as the type and amount of

colloid present.

Another benign diagnosis is Hashimoto's thyroiditis; it has a fairly

characteristic pattern on FNA smears, showing hypercellularity with

lymphocytes, Hürthle cells, and minimal or no colloid

This is what my Biopsy report says..

follicular epithelium, colloid, blood, and rare macrophages.

So no lympocytes or hurthle cells means no Hashi's and the thyroid

is normal..

Although a high TPO in the 100's or higher usually indicates

Hashimoto's I know some on the Grave's board that have TPO's in the

1000's, and any medical source that I find reliable with scientific

background have all said FNA is the only true test for Hashimoto's

although up until a few years ago TPO was believed to be the test

for it, now it is seen only as an inflammatory marker of the thyroid.

Kats3boys

[Guest guest]

>

> Hi,

>

> I've been reading your comments.. and have learned so much. Can you

> tell me what FNA is all about? I do have hashi according to an

> antibodies test they've done and I'm just curious if that shows just

> an inflamation situation or would that be a true test for hashi's.

> Also does FNA distinguish to the point of graves vs hashi's?

>

> Thanks Connie

>

FNA is a fine needle autopsy in which the ENDO in his office draws

small tissue samples from the thyroid.. generally it is done on

nodules to detect cell changes, but it can also be done on a normal or

enlarged thyroid with out nodules.

With Hashimoto's the antibodies attack the thyroid, causing damage to

the thyroid, this damage causes high TPO antibodies as TPO is released

from the thyroid during antibody attacks.

With Hashimoto's they look for lack of Colloid and lymphocyte

infiltration..to my knowledge this is the only auto immune test that

can be picked up by FNA. Other thyroid disorders are also diagnosed by

FNA but not Grave's that I know of..

Kats3boys

[Guest guest]

>

> Hi Kats,

>

> My TPO is >1000 so I have hashis, hypo and goiter, no nodules.

>

> On the allergies, that makes sense, if you swell or get hives,

you are

> allergic.

>

> So that would be different than an intolerance or sensitivity to,

such as

> lactose, right?

> I get bloated and gassy if I have even half a glass of milk for

example.

>

> Sometimes I have noticed though, that I get hives or my lips get

itchy and

> ³tight² and I always wondered what that was...am thinking now it¹s

a mild

> allergy so I will keep a look out for that.

>

> Sounds like you have done a TON of research on this ‹ you have an

amazing

> amount of info!

>

> Overall, what do you want to do as far as treatment? I know you

are playing

> the waiting game, but why are you ³swinging² so much with hyper to

hypo?

> That has to feel pretty bad.

>

> Sue

>

>

I actually have not had the hypo swing yet.. just the hyper and

normal and back and forth.. for treatment I just want my allergies

to go away..if work gets worse I may have to quit due to allergies

and it would be nice to not be sitting here sweating and shakey and

to be able to exercise with out worrying about my heart trate..

I think a partial may be the way to go if I had no other options.

Kats3boys

[Guest guest]

Kat

Your Hashis testing still says that you could be, mainly because of the low reading at the top of the range for the TPO (the 34, in a range that goes to 35), Hashi's, no matter what they are telling you. Is it possible for an FNA to tell the whole story on Hashis? I thought that actually physically looking at the gland was what tells the whole story there. I don't think that all Hashis sufferers experience exactly the same things at different points in time, in the same order. Could be that, because your thyroid disorder was discovered at an earlier point in time, the Hashis may simply be at an earlier stage. It would be nice if you could have both those antibody tests run a couple of times a yr to see the metamorphosis of what could easily still be Hashis.

..