Guest guest Posted December 5, 2004 Report Share Posted December 5, 2004 In a message dated 12/5/2004 7:43:56 A.M. Central Standard Time, bdavis66@... writes: I have had a different experience with warfarin--my INR jumps all over the place which doesn't happen for me with Coumadin. Although it's not scientific evidence my doctor has noted similar problems with some, but not all, his patients on anticoagulants and we agreed that I should take only Coumadin. My pharmacist says that the actual drugs in generics are the same, but it is the fillers, etc. that are different and can cause problems in some people, but again not all. So it appears to be (yet again) an individual thing with us afibbers. Brenta This is exactly what I found out. I was having a hard time getting my INR stabilized and when I was talking to the Cardio. Nurse about it, I asked if she thought it could be because I had been switched from coumadin to warfarin. She was upset to find this out because her office does not prescribe warfarin. I think there was a new nurse in the office who was, sincerely trying to save me some money. When we switched back to coumadin my INR stabilized. I have also read that, while the chemical content is the same, the filler can differ. I think this can effect the rate of absorption---- which still doesn't explain the variable INR. Guy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2004 Report Share Posted December 5, 2004 Here are a couple of spots you may want to look http://www.fda.gov/cder/ogd/ http://www.fda.gov/cder/consumerinfo/generics_q & a.htm I've taken warfarin for a long time. There appears to be no batch to batch variation that I can notice. Bill Manson " If you don't have time to read the comics, you don't have a life. " -- Marcia G. Kennedy Coumadin vs Warfarin Thank goodness you folks are here. Has anyone found an unbiased report on the differences between warfarin and coumadin? I'd like to go on the generic for the cost savings, but then I read articles about how this drug needs to be more precise than most others where a generic is OK. One of the sites that says this is the coaguchek site, owned by Dupont Pharm. Interestingly enough, I see Dupont Pharm. was bought some time ago by Bristol Myers who makes Coumadin. How convenient. Of course, warfarinfo.com shows there is no difference. Help? Web Page - http://www.afibsupport.com List owner: AFIBsupport-owner For help on how to use the group, including how to drive it via email, send a blank email to AFIBsupport-help Nothing in this message should be considered as medical advice, or should be acted upon without consultation with one's physician. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2004 Report Share Posted December 5, 2004 I have had a different experience with warfarin--my INR jumps all over the place which doesn't happen for me with Coumadin. Although it's not scientific evidence my doctor has noted similar problems with some, but not all, his patients on anticoagulants and we agreed that I should take only Coumadin. My pharmacist says that the actual drugs in generics are the same, but it is the fillers, etc. that are different and can cause problems in some people, but again not all. So it appears to be (yet again) an individual thing with us afibbers. Brenta Coumadin vs Warfarin > > > > Thank goodness you folks are here. Has anyone found an unbiased > report on the differences between warfarin and coumadin? I'd like to > go on the generic for the cost savings, but then I read articles > about how this drug needs to be more precise than most others where a > generic is OK. One of the sites that says this is the coaguchek > site, owned by Dupont Pharm. Interestingly enough, I see Dupont > Pharm. was bought some time ago by Bristol Myers who makes Coumadin. > How convenient. Of course, warfarinfo.com shows there is no > difference. > > Help? > > > > > > Web Page - http://www.afibsupport.com > List owner: AFIBsupport-owner > For help on how to use the group, including how to drive it via email, > send a blank email to AFIBsupport-help > > Nothing in this message should be considered as medical advice, or should > be acted upon without consultation with one's physician. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 6, 2004 Report Share Posted December 6, 2004 It's also true that the supplier of warfarin to any given pharmacy changes regularly in a totally unpredictable fashion, so not only do " fillers " change among manufacturers, they change for us all the time. My INR, too, was all over the map on warfarin, then stabilized almost immediately on coumadin. Kathleen (24/7, digoxin, atenolol, coumadin). Incidentally, some HMO's refuse to allow anything but generic warfarin despite these individual patient problems; good medicine, huh? Quote Link to comment Share on other sites More sharing options...
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