RE: Recent (and ongoing) LDN IBD findings

[Guest guest]

My LDN research has been only slightly more extensive, though I

did manage to find references to the medical research:

http://tinyurl.com/d4ck7t

" Low-dose naltrexone therapy improves active Crohn's disease "

http://tinyurl.com/d7k9pb

" The opioid antagonist naltrexone improves murine inflammatory

bowel disease "

I came across a variety of discussion boards offering personal

opinions and experiences:

http://tinyurl.com/dektkl

http://tinyurl.com/d3xna4

http://tinyurl.com/dmrust

I have not yet tried LDN, but as I finish tapering off of my

latest round of Prednisone (to get my UC flare under control) I

will probably try to obtain a prescription for LDN as an

experiment. Personally, having been on SCD for 5 months now, I

am willing to give it 2 to 3 years to work, but in the meantime

if there is an alternative to Prednisone steroid to keep my UC

flares in remission then I'll try it... and LDN is supposedly a

drug with very little side effects.

cmd@...

Re: [ulcerative_Colitis] Re: Recent (and ongoing) LDN IBD findings

I just spent about 15 minutes looking up LDN and was unable to find really

anything other than anecdotal sites saying it has no side effects and works

great. If you have an actual medical site that discusses it, I'd like to

look at it, but sorry, it's hard to give credibility to something that

appears to not really have any documentation.

As far as your comments about remicade never working, if that's the

argument, then there are NO drugs that " work " for UC, because there are no

drugs that cure UC. All drugs carry the possibility that they won't work

after a certain time frame. That doesn't mean they just don't work. It

means that the disease is very individual, and what works long-term for one

person might not work for another. I've been on Colazal for 3 1/2 years,

and have been in remission for most of that time. If I have a flare up,

that doesn't mean that Colazal didn't work at all. It most certainly has.

Amy

[ulcerative_Colitis] Recent (and ongoing) LDN IBD findings

> To: btvc-scd , pecanbread ,

> ulcerative_colitis

> Date: Monday, April 13, 2009, 3:19 PM

>

> I inquired about the status of the latest U.S. study involving

> the use of low dose naltrexone to treat Crohn's and colitis, as I

> am interested in perhaps trying LDN to help keep my IBD/UC flares

> in remission, and the following is the feedback that I received

> (this is being shared with her consent):

>

> ----------------------------------------------------------

>

> We are currently studying naltrexone in Crohn's disease and our

> studies can be found on www.clinicaltrials.gov

>

> I hold the license through an IND# from the FDA to treat subjects

> with IBD. I have treated some patients with ulcerative colitis

> with success but we currently are not conducting a trial. Our

> publication in Immunotoxicology Journal last year supports that

> it should work in UC and the rationale for the dosing.

>

> I know that Remicade does not work in UC.

>

>

> Jill , MD

>

> ----------------------------------------------------------

>

>