Guest guest Posted November 21, 2007 Report Share Posted November 21, 2007 http://jcem.endojournals.org/cgi/content/abstract/77/2/404 -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2007 Report Share Posted November 22, 2007 Does it make adrenals more responsive in a good or worsening way? > > Basically that aspirin makes the whole adrenal system more responsive, > but overall has little effect oin cortiosl levels. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2007 Report Share Posted November 22, 2007 It soulds to me more like ti sensitizes the adrenals as it doesn't create more cortiosl. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2007 Report Share Posted November 22, 2007 Valarie, I have always wondered but really had no one I could ask: If candita is aan issue,could hormone receptor cites be gunked up and maybe the aspirin helps clean them off? I do not do the aspirin therapy my doctors are now advising,but it might be helpful for some things. Yes,I am very thankful for you and all the members. You are a miracle and helping many others with your knowledge and experience. Have a wonderful holiday. Best Regards,Pat Re: AF & aspirin Basically that aspirin makes the whole adrenal system more responsive, but overall has little effect oin cortiosl levels. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.503 / Virus Database: 269.16.2/1143 - Release Date: 11/21/2007 10:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2007 Report Share Posted November 22, 2007 Well I am no help here as I have not heard of this aspirin therapy of which you speak. Candida is a normal fungus of the human body and onyl becomes a problem when our temps are off and our immune systems too weak to keep it in check at normal levels and it proliferates to become a problem. I have not heard of Candida blocking receptors. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2007 Report Share Posted November 26, 2007 --- At 07:04 AM 11/21/2007, pary82 wrote: > >How does aspirin affect adrenals, does anyone have info about this? >Thank you!! " In the body, nitric oxide is synthesized from arginine and oxygen by the enzyme nitric oxide synthase (NOS) and requires the presence of calcium for its production. NOS synthesizes NO depending on the availability of L-arginine [...] In the adrenal gland, NOS is highly concentrated in a web of neurons that stimulate adrenal cells to make adrenaline. " from: http://biologyofkundalini.com/article.php?story=NitricOxide " When hypomagnesia is present, or/and the ratio magnesium/calcium is low (lots of calcium, relatively low magnesium levels), the excess calcium levels will cause excess calcium influx into all living cells. This is because magnesium, can only act as a calcium-channel blocker if it is in the right balance with calcium. The calcium influx will cause nitric oxide (NO) synthesis inside the cells. The NO suppresses the adrenals, causing adrenal sufficiency. The low cortisol levels will further increase NO synthesis. This is because the low cortisol levels are making the immune system hyper. This means upregulated nitric oxide and other cytokines. The increased nitric oxide levels will further depress the adrenals. Vicious Cycle. " from: http://www.newtreatments.org/cfs " Aspirin is a nitric oxide inhibitor Aspirin is a nitric oxide inhibitor and can be of great value to people with inflammatory illness. (Taking three aspirin can relieve severe bouts of fatigue within thirty minutes.) " from: http://web.archive.org/web/19990831011545/www.seaquake.com/licorice.html --- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2007 Report Share Posted November 26, 2007 --- the following is from: List of Vitamins Nutrients, Herbs and Drugs Used to Recover From Chronic Fatigue Syndrome and Fibromyalgia! by Captain <http://web.archive.org/web/19991011230652/http://www.seaquake.com/cfs-fm-recove\ ry/meds1.html> " Using a NO inhibitor, such as aspirin, just before exercising will help to lower NO [nitric oxide] production and should relieve most of the post-exercise fatigue. More on aspirin can be found below. [...] Aspirin Special note: Aspirin is a great agent for temporary relief of fatigue in CFS/FM. However, if you suffer a lot of food related headaches, you do not want to take a lot of aspirin or other similar drugs because you likely have leaky gut syndrome and these agents will only increase the problems from the leaky gut! But if you do not have a lot of headaches, aspirin reduces NO levels (abstract) >> <http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve & db=PubMed & list_uids=75355\ 24> and may be a great drug to use when you must. Nitric oxide regulates the production of cyclooxygenase (COX), the enzyme that converts arachidonic acid to prostaglandins. COX is known to exist in two separate forms, called COX-1 and COX-2. While both forms catalyse the same reactions, COX-1 is a constitutive enzyme and its activity is not markedly changed once the cell is fully grown. -2 is inducible and its activity is several fold increased following the exposure of body cells to a number of stimuli and its contribution in the process of inflammation is now well documented. Older nonsteroidal anti-inflammatory drugs like aspirin and indomethacin are non selective inhibitors of COX activity and therefore, can break the NO pathway and reduce the hypotensive effects of excessive nitric oxide and prostaglandin production. The next time you notice severe fatigue, try three or four plain aspirin. If fatigue is relieved within 30 minutes, you'll know you're on the right tract in following this program to reduce your NO levels. Licorice protects the stomach from high-doses of aspirin. Still, high-doses are not recommended for long periods. Try to reduce NO levels by the other means and take only two or three aspirin as needed. Aspirin comes in handy when exercising. Increasing the heart rate and the physical flow of blood through the vessels stimulates NO " primed " immune cells in the blood to release high levels of nitric oxide resulting in increased symptoms after exercise. However, two aspirin taken before you start your activity will serve to counter the increase in NO and prevent the flare after exercise. Aspirin is a prostaglandin inhibitor and will help relieve neurally mediated hypotension if the person is properly hydrated and not suffering from low blood volume. (see below) In addition, prostaglandin is upregulated by the low cortisol levels found in CFS. Prostaglandin can lead to sodium loss and reduced water retention, also noted in CFS. Therefore, the difficulty you have in retaining fluids should be markedly improved by taking aspirin. Matter of fact, you should be able to notice improved fluid retention several hours after taking aspirin if you also drink plenty of fluids. One or two tablets per day will not hurt you unless you are allergic to aspirin. You body can also grow accustomed to taking the drug by starting one tablet per day and slowly increasing the dose to two. " --- the following is from: Chronic Fatigue and Fibromyalgia - A nitric oxide vicious cycle http://www.newtreatments.org/cfs Eating lots of carbohydrates will cause excess magnesium excretion, which will result in a low magnesium/calcium ratio Not enough magnesium left to act as calcium channel blocker, result: Increased calcium influx Calcium influx will cause excess NO production High NO levels will suppress adrenal hormone production Low adrenal hormone levels will further increase high NO, inducing a viscous cycle Other ways to start the NO vicious cycle Of course, the magnesium deficiency is just one way to start the vicious cycle. Any condition that causes excess NO will be able to start the vicious cycle. Think of intestinal bacteria, a viral infection, zinc deficiency, low antioxidant status, elevated stress levels for prolonged times. How does adrenal insufficiency cause low blood pressure, hyperkalemia and sodium deficiency ? The adrenals produce cortisol, but also aldosterone, which regulates blood pressure, sodium and potassium balance. Low levels of aldosterone will cause the hyperkalemia, the sodium deficiency and the low blood pressure. Besides that, NO is a potent vasodilator. Excess NO levels in the blood will cause low blood pressure. " --- Quote Link to comment Share on other sites More sharing options...
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