Topper - 's Labs

March 12, 2006

Here's everything I could dig out of 's immense lab binder since

October that's hormone related.

Ami

TSH: 0.4 - 5.0

fT4: 0.7 - 1.85

TT4: 5.5 - 12.8

10/26 . . . TSH: 14.55 . . . fT4: 1.15

10/29 . . . Parathormone (Intact): <3 . . . TSH: 18.69 . . . fT4:

1.33

11/4 . . . TSH: 2.86 . . . fT4: 1.92

11/10 . . . TSH: ?.?? . . . fT4: 1.27

Somewhere in this vicinity, his levo began being crushed and given

through his G-tube into his stomach. We see how well THAT goes over.

11/22 . . . TSH: 103.29 . . . fT4: 0.89

Obviously THAT wasn't what we want happening, so they begin IV

thyroid instead.

12/6 . . . TSH: 114.42 . . . fT4: 1.18

12/8 . . . TSH: 125.00 . . . Beta hCG Tumor Marker <3 (<5)

12/12 . . . TSH: 67.27 . . . fT4: 1.02 . . . T3: 102 ng/dL . . .

TT4: 7.9 . . . Alpha-Subunit Pituitary Glyco-Protein: 0.57 (Males

<50 - 0.10 - 0.55) . . . Beta hCG Tumor Marker: <3 (<5) . . .

Prolactin: 20 ug/L . . . Adrenal Corticotropin: 20 pg/mL (9 am -

<10 - 50 . . . midnight - <10)

12/13 . . . Aldosterone: 4.4 (4.0 - 44.0) . . . Renin: 1.7 (Children

6 - 10 yrs - 0.5 - 5.9)

12/15 . . . TSH: 61.00 . . . fT4: 1.04 . . . T3: 119

12/19 . . . TSH: 59.30 . . . fT4: 1.42 . . . T3: 180

12/26 . . . TSH: 49.69 . . . fT4: 1.19 . . . T3: 137 . . . TT4: 10.6

1/23 . . . TSH: 48.04 . . . fT4: 6.23

In this range, we begin putting his thyroid med in his tube again,

though in the J-tube this time (into his intestine). Obviously

wasn't working QUITE as well as the IV version due to his lack of

proper absorbtion, but he does start coming back down. And his fT4

starts coming up. Yet he's still way outside normal. It's nuts.

That's all I know.

2/7 . . . TSH: 67.33 . . . fT4: 1.25

2/16 . . . TSH: 31.49 . . . fT4: 2.17

2/26 . . . TSH: 32.32 . . . fT4: 1.68 . . . T3: 172

March 14, 2006

He's had several different antibody tests done along the way, and I

don't have all those labs (we've been playing with various things

over the last 18 months or so, and a lot of stuff is at home, where I

haven't been in almost 7 months). However, I can tell you his

thyroid (anti-thyroid?) antibodies the first time (last Feb?) were

<1.5 (which I was told here basically meant non-existant - not to

worry). They were rechecked here in August, September, something

like that. At that time it was 13, which I was told was too low to

be considered positive.

I did have one person here, (at the hospital, not here the group) say

she thought maybe he'd had Hashi's and we caught it during his

thyroid's last efforts to defend itself (rephrasing however she

worded it). And basically his thryoid was fizzling out by the time

we caught it.

How would the aldosterone/renin thing affect his bp? It's normally

in the 90/60 - 100/70 ish range. Been a bit higher last couple weeks

or so, but he's been in pain and on immunosuppressant meds and such.

So that accounts for a lot of that.

Part of my curiosity with that MRI is not only the spot on his

pituitary, but his pituitary stalk. I'm still not fully convinced

that he does NOT have LCH. His lung and liver diseases, both

uncommon in children, are the same ones you find in children with

LCH. Along with the DI and hypoT.

Ami

>

> Ami

March 14, 2006