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Week in Review - Medscape Today MedPulse®

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MIGRAINE: Free Slide Kit and Speaker's NotesThis eight-chapter slide kit includes sections on the different types of headaches, various migraine treatments and treatment strategies and the impact of migraine (such as direct and indirect costs and workplace disability). There are a total of 240 slides.Click here to download. Brought to you by Attack-Migraine.com.

ALSO IN THIS ISSUE:MEMBER NEWSUSER SUPPORT

NEW FEATURES THIS WEEK

THIS WEEK

Policy Decision Options During the First 5 Years Following Certification of Polio Eradication

Authors from Harvard and the CDC explore the policy and programmatic options to be faced by countries following certification of eradication of poliomyelitis.Medscape General Medicine 5(4) 2003

Editorial - Polio and Policy Options

Dr. Foege contributes to the debate surrounding policy and programmatic options to be faced by countries following certification of eradication of poliomyelitis.

Instant Poll - Plans for Medicare Patients

In a Medscape Instant Poll that launched Dec. 15, 66% of respondents said that now that Congress has voted to increase physician payments for Medicare by at least 1.5% in the next two years, they do not plan to make any changes to their volume of Medicare patients. But 24% of respondents said they will continue to limit their Medicare patient volume. As of Dec. 18, a total of 392 respondents had taken part in this poll.

CARDIAC RHYTHM MANAGEMENT

Benefits of Cardiac Resynchronization Therapy Sustained For at Least 24 Months

CRT improves quality of life, functional status, and exercise capacity in heart failure patients and the benefits are sustained through at least 24 months, regardless of disease etiology.Medscape CRM News2003

CARDIOLOGY

HFSA Meeting -- TEN-HMS, COMET, and CHARM Trials

Should digoxin be dropped? Does "diastolic heart failure" really exist? Are the heart and the uterus closely related? Barry Greenberg, MD, reviews both the new and the controversial information presented at the HFSA meeting.Medscape 2003

Subacute Stent Thrombosis and the Sirolimus-Eluting Cypher Stent: A Physician's Perspective

Recent warnings issued by the Food and Drug Administration regarding the risk of subacute stent thrombosis associated with the implantation of the Cypher sirolimus-eluting stent may be overstated.

CRITICAL CARE

Journal Scan

Review articles on morbidity and mortality in ARDS, the cause of mortality in cardiogenic shock, patient outcomes after discharge from a hospital-based weaning unit, end of life in a pediatric ICUMedscape Critical Care 4(2) 2003

DERMATOLOGY

The Management of Regional Lymph Nodes in Cancer

In light of current knowledge, does it make sense to perform surgical dissection of regional lymph nodes in patients with cancer?Br J Dermatol 149(5) 2003

Oral Lichen Planus Part I

Dermatologists, dentists, otorhinolaryngologists, and other specialists who deal with the oral cavity must be aware of this disease so they can diagnose, treat, and keep these patients under observation.

Netherton Syndrome

A 17-year-old Egyptian patient presented to the dermatology clinic of Al-Ain Hospital with a complaints of pruritic dry skin and short brittle hair since early infancy.

DIABETES & ENDOCRINOLOGY

Peripheral Arterial Disease in People With Diabetes

It is important to diagnose PAD in patients with diabetes to elicit symptoms, prevent disability and limb loss, and identify patients at high risk of MI, stroke, and death.Diabetes Care 26(12) 2003

Insulin is Required for Prandial Ghrelin Suppression in Humans

The role played by insulin in postprandial regulation of plasma ghrelin concentrations may have a physiologic and clinical impact in modulating the feeling of hunger.

Thyroid Hormone Action on Brain Development and Function

Do thyroid hormone receptors have an impact on behavior?

FAMILY MEDICINE

ACP/AAFP Issues Guidelines for Management of Atrial Fibrillation

The joint commission made six recommendations for internists and family physicians to manage patients with atrial fibrillation, except for those cases occurring after surgery or MI.Medscape Medical News2003

GASTROENTEROLOGY

Surgical Management of Achalasia

Brant Oelschlager, MD, and A. Pellegrini, MD, discuss and demonstrate, the surgical approach to a 37-year-old woman with a 2-year history of progressive dysphagia to both solids and liquids.Medscape General Medicine 5(4) 2003

Journal Scan - Acid-Related Disorders

Learn about long-term endoscopic surveillance of patients with Barrett's esophagus, deciding which patients with reflux symptoms require endoscopy, and more.

HIV/AIDS

Conference Report - Antiretroviral Therapy Update From the 9th European AIDS Conference

When should clinicians start therapy and what should they use? What should one do next when there is a need or desire to modify therapy?Medscape General Medicine 5(4) 2003

Counterfeit Antiretroviral Drugs

HIV clinicians in the developing world have yet another challenge: screening out counterfeit antiretrovirals.

HIV-1-Infected Antiretroviral-Treated Patients With Prolonged Partial Viral Suppression

Achieving and maintaining undetectable viremia is the goal of antiretroviral therapy (ART), but a significant proportion of HIV-1-infected patients do not attain this goal.

HEMATOLOGY-ONCOLOGY

Advances in the Management of Essential Thrombocythemia and Polycythemia Vera

Dr. M. Fruchtman, of the Mount Sinai Medical Center in New York, discusses some of the latest therapeutic options being studied in the management of ET and PV.Medscape 2003

INFECTIOUS DISEASES

Journal Scan - Infectious Diseases

VRE control in livestock; linezolid vs vancomycin in nosocomial pneumonia; community-acquired MRSA skin infections; malaria prophylaxis; West Nile update; ventilator pneumonia decision analysis & moreMedscape Infectious Diseases 5(2) 2003

Comparative Molecular and Microbiologic Diagnosis of Bacterial Endocarditis

According to the earliest published report on the subject, the prevalence of blood culture-negative endocarditis once ranged from 2.5% to 31%.

INTERNAL MEDICINE

Fitness Important for Cardiovascular Health

The protective role of fitness was independent of other cardiovascular risk factors except for weight, according to a longitudinal population cohort study.Medscape Medical News2003

Microalbuminuria Linked to Cardiac Risk in Hypertensive Patients With LVH

Based on the prospective LIFE study, the investigators suggest that detection of microalbuminuria in hypertensive patients may help the clinician decide when to start therapy.

MOLECULAR MEDICINE

Commentary - Neuroethics: How To Leave the Cave Without Going Astray

"I am much more than my genes, they are not my essence, they are not my soul; is then my consciousness, my brain me?" Experts discuss identity at the American Society of Neuroscience meeting.Medscape General Medicine 5(4) 2003

Commercial Enzyme Immunoassays and Genital Infections With Herpes Simplex Virus Types 1 or 2

Most patients with genital herpes are unaware of their infection status, partly because the disease can be mild or mistaken for other syndromes by clinicians and patients.

MONEY & MEDICINE

No IT Revolution Yet, But Forces Amassing

Much of the healthcare industry is still a long way from the technological sophistication commonplace in most other industries. What forces are holding hospitals and doctors back?Medscape Money & Medicine 4(2) 2003

Journal Scan - Patient Safety

Read this month's Journal Scan to learn more about how hospitals rank their medication safety practices, the link between surgeries and mortality, and more.

The Medicare World From Both Sides: A Conversation With Tom Scully

The CEO of the nation's largest health insurer, Medicare, defends the Bush Administration's focus on the private sector as the way forward for Medicare.

NEUROLOGY & NEUROSURGERY

Ergoloid Mesylates for Dementia

Do these agents have utility in the management of Alzheimer's disease or other dementias?Medscape Neurology & Neurosurgery 5(2) 2003

Spontaneous Intracranial Hypotension Often Misdiagnosed

Failure to recognize this condition may cause significant delay in treatment and risks of mistreatment.

Microendoscopic Discectomy for Recurrent Disc Herniations

Recurrent lumbar disc disease (reherniation on the same side and at the same level where a previous discectomy had been performed) can present a formidable challenge in the treatment of patients with radiculopathy.

NURSING

Conference Coverage - National Association of Neonatal Nurses

Topics covered include the latest research on neonatal skin care, prevention of premature birth, and the future of neonatal nursing.Medscape 2003

Sleep Problems in Pediatric Practice: Clinical Issues for the Pediatric Nurse Practitioner

Learn about the resources available to help with pediatric sleep problems in clinical practice.

Alternating Acetaminophen and Ibuprofen in the Febrile Child

Despite the long-term practice of alternating acetaminophen and ibuprophen in febrile children, what is the evidence base for this practice?

OB/GYN AND WOMEN'S HEALTH

Conference Report - American Association of Gynecologic Laparoscopists 32nd Annual Meeting

Highlights of the meeting included discussion of medical and surgical procedures for fibroid treatment, endometrial ablation techniques, and the new hysteroscopic method of sterilization. Medscape Ob/Gyn & Women's Health 8(2) 2003

Achieving Equity in Women's and Perinatal Health

The large disparities between different racial and ethnic groups with regard to women's and perinatal health outcomes in the United States was the topic of this year's symposium, Autumn in New York.

OPHTHALMOLOGY

Conference Coverage - American Academy of Ophthalmology Meeting

Topics under debate included the uses of intravitreal corticosteroids as treatment for retinal disease, aggressive therapy for ocular inflammatory disease and more.Medscape 2003

Clostridial Endophthalmitis After Cornea Transplantation

Endophthalmitis is a severe condition caused by inflammation of the ocular cavity that often is associated with infection of the internal structures of the eye.

ORTHOPAEDICS

Giant-Cell Tumor of the Tendon Sheath

A 63-year old man presents with a long-standing soft-tissue mass at the volar aspect of his right PIP joint.Appl Radiol 32(10) 2003

PEDIATRICS

Overview of the CDC Growth Charts

The three self-directed, interactive training modules included in this activity are designed to enhance expertise in using and interpreting BMI-for-age growth charts. Medscape 2003

Journal Scan - Child and Adolescent Psychiatry

The association between maternal smoking and ADHD is the subject of one of many studies covered in this month's Journal Scan.

PHARMACOTHERAPY

Systemic Antifungal Therapy: New Options, New Challenges

The frequency of invasive mycoses has increased dramatically during the past 2 decades owing to medical advances.Pharmacotherapy 23(11) 2003

Continuous Versus Intermittent Infusion of Piperacillin-Tazobactam

The use of continuous infusion as a means of administering piperacillin tazobactam was more cost-efficient than intermittent infusion of the drug.

PRIMARY CARE

Antireflux Surgery in the Era of Proton-Pump Inhibitors

This comprehensive article updates us on the pros and cons of antireflux surgery and medical management of gastroesophageal reflux disease.Medscape Gastroenterology 5(2) 2003

How to Boost Your Bottom Line With An Office Procedure

Adding joint and soft-tissue injection to your practice can pay off in more ways than one.

PSYCHIATRY

Side Effects in the Treatment of Bipolar Affective Disorder

Many, if not most, bipolar patients require multiple medications in order to effectively control their symptoms.Medscape Psychiatry & Mental Health 8(2) 2003

Bipolar Depression: 6 Questions

Treatment of bipolar disorder depression is complicated. Studies suggest that people with bipolar disorder spend up to 33% of their adult lives in depression.

Journal Scan - Psychiatry

Binge eating, arthritis and depression, and delirium are among the topics discussed in this month's Journal Scan.

PUBLIC HEALTH & PREVENTION

Research and Practice - Environmental Tobacco Smoke

A study indicates for the first time that both cumulative lifetime and recent environmental tobacco smoke exposures increase the risk of adult-onset asthma.

Am J Public Health 93(12) 2003

PULMONARY MEDICINE

Inhaled Steroids in Steroid-Resistant Asthma

Are inhaled steroids still indicated in cases of proven steroid-resistant asthma?Medscape Pulmonary Medicine 5(2) 2003

RADIOLOGY

Journal Scan - Radiology

Do large uterine fibroids place the patient at higher risk in cases in which uterine artery embolization (UAE) is undertaken? Read about this and more.

Medscape Radiology 4(2) 2003

Disseminated Nocardia Asteroides Infection With Pulmonary and Cerebral Abscesses

A 42-year-old man who has undergone a pancreatic and renal transplant 6 months earlier presents to his primary caregiver with a persistent cough and onset of hallucinations.

RHEUMATOLOGY

Juvenile Polyarticular Arthritis Associated With Persistent Parvovirus B19 Infection

Use of IVIG to treat parvovirus B19-triggered polyarticular rheumatic disease of childhood might offer an opportunity to improve this disabling condition.Arthritis Res Ther 6(1) 2003

New Horizons in TNF Inhibition - Topic 1: Treating Ankylosing Spondylitis

Examine the full spectrum of management issues for ankylosing spondylitis, including diagnosis, disease scoring systems, and treatment.

Interferon-b-1a (Avonex) in Patients With Rheumatoid Arthritis

No one therapy or combination of therapies works for all patients, patients who do respond rarely achieve remission, therapy can lose efficacy over time, and side effects can limit the utility of any therapy.

TRANSPLANTATION

Conference Coverage - American Society of Nephrology Renal Week 2003

Experts discuss risk of cardiovascular disease and death in patients with chronic kidney disease, severe hyperparathyroidism, metabolic and immunologic complications in renal transplantation, and more.Medscape 2003

Journal Scan

Preventing bone loss with vitamin D, MMF-induced reversal of GFR loss in children with chronic allograft nephropathy, use of candesartan cilexetil in renal transplant patients, and more.

UROLOGY

Erectile Dysfunctions

Normal aging, as well as psychogenic, vascular, neurogenic, and endocrinologic causes and/or those due to structural abnormalities of the penis should be considered when evaluating details to determine its probable cause. SKINmed 2(6) 2003

Fracture of the Testicle

A healthy 22-year-old man presented to the emergency department 30 minutes following acute scrotal trauma.

RA DISEASE AND IMMUNE RESPONSE

Do rheumatoid arthritis patients have a polarized immune response? Review findings on the selective accumulation of Th1 and Th0 cells

in inflamed synovium. Read "Decreased Response to IL-12 and IL-18 of Peripheral Blood Cells in Rheumatoid Arthritis," a featured article

in the Rheumatoid Arthritis Resource Center.

MEMBER NEWS

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