synoval lining inflamation

[Guest guest]

Dolores and Mike,

 

here is a little info on the problem I told you I have with my hands.

 

Key proteins identified in inflammation of joints

     Hopkins medical researchers have found a key link in the

chain reaction that causes inflammation of the lining of the

joints in arthritis. The discovery may aid the search for drugs

that suppress or control these events before the joints are

damaged.

     The scientists found that activation of two types of

molecules called G-proteins is part of a cascade of signals that

causes the lining of the joints to become inflamed. The reaction

begins when bradykinin, a small protein, binds with special

receptors on the outside of the cells making up the lining of the

joints. The G-proteins are in the cellular " skin " of this lining,

called the synovium, which is rich in bradykinin receptors.

     " This study provides the first direct evidence that

G-proteins connect the pathways to bradykinin receptors in human

synovial cells, " said Helen , the study's lead author.

" Now the goal is to develop strategies to block the pathways and

to develop new anti-inflammatory drugs that can do that job. "

     Currently available anti-inflammatory drugs for the most

part have been disappointing, making it logical to investigate

other ways to prevent or control inflammation, said. 

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anyway, Burl and I had a great time in Corpus Christi and it was nice seeing you

and you doing so well. I am looking forward of getting well too soon. Guess as I

told you I am a little impatient and want to get well now, but I can wait a

little while longer.

We got home before 11 am this morning. No problem with the weather.

Take care,

Eva and Burl