Re: question for those who have been on SCD for a long time - AJ

[Guest guest]

To: AJ (scd_diet@...), posted Fri May 1, 2009, 1:13pm (PDT)

Hi,

Thank you for the interesting info' on why Ebringer implicates Kp (Klebsiella pneumonia) as possible cause for Crohn's and Ulcerative Colitis. I've read your email several times and think I understand the majority of what you've written.

However, when you have time, I have a few questions:

1. Does Kp produce the de-branching enzyme that it uses to attack a complex starch (like amylopectin) or is that particular enzyme produced by another component?

2. You've written, "If I eat more cashews, almonds, and peanuts, my stool gets loose and I can culture Kp. If I do not, the bacteria don't show up."

Does this mean, those of us who follow SCD, should be careful how many cashews, almonds, and peanuts we consume? And if "yes", what is too much?

Info' available on 8-track cassette and stone tablets? If you have any tapes on beta, I may be interested.

Well wishes to all. ferna, UC/CD, SCD 95, 06, No Meds

Can't afford a new spring wardrobe? Go shopping in your closet instead!

[Guest guest]

Sorry to hear you spent 6-12 hours reading my stuff more than once.

Your questions:

1) Kp produces pullulanase- the de-branching enzyme- to attack amylopectin, yes.

Some of the proteins used in making pullulanase (pulA and pulD secretion

proteins) as well as klebsiella nitrogenase may have the same sequence. The

literature is a little thick and tough for me to determine who thinks what.

Also note there's been another, more recent paper in which various

bifidobacteria may produce pullulan-degrading enzymes. Now, they don't come

right out and say " pullulanase, " but the implication is there. If accurate, this

could explain why bifidobacteria are no-no on the Gottschall diet: they may

produce enzymes that are sufficiently similar to those from Klebsiella

pneumoniae to act as triggers (!).

Also note there are enough differences between enzymes that while pullulanase

from Kp may be sensitizing, the enzyme from another organism may not. Just tiny

differences may be enough. However, the reverse may be true: pullulanase from

OTHER organisms *might* be enough to sensitize the immune system. It's not the

enzyme itself causing the sensitization- but the code in its molecular

structure.

2) I believe I kind of answered this in the previous email which you probably

received just now, or will receive soon. Different people, different

sensitivities. But there is an explanation for all these differences- we're just

not there yet in terms of science. Peanuts and cashews are my " problem " species.

Almonds seem to be OK, same as pecans.

-AJ

> Thank you for the interesting info' on why Ebringer implicates Kp (Klebsiella

pneumonia) as possible cause for Crohn's and Ulcerative Colitis.? I've read your

email several times and think I understand the majority of what you've written.

>

> However, when you have time, I have a few questions:

>

> 1.? Does Kp produce the de-branching enzyme that it uses to attack a complex

starch (like amylopectin) or is that particular enzyme produced by another

component?

>

> 2.? You've written, " If I eat more cashews, almonds, and peanuts, my stool

gets loose and I can culture Kp.? If I do not, the bacteria don't show up. "

>

> Does this mean, those of us who follow SCD, should be careful how many

cashews, almonds, and peanuts we consume?? And if " yes " , what is too much?

>

> Info' available on 8-track cassette and stone tablets?? If you have any tapes

on beta, I may be interested.

> ?

> Well wishes to all.? ferna, UC/CD, SCD 95, 06, No Meds

>