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Steroids and hypothyroid?

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Does anyone know how massive amounts of intravenous and oral steroids

can affect the thyroid?

> > Hi -- I love this board. You guys are WONDERFUL!!!

> >

> > Long story short -- I have been on Armour thyroid, 120 mg (2

> grains),

> > taken in a divided dose, twice a day, for 5 years. It's been a

> life

> > saver. A few years ago my doc tested my adrenals, and found I had

> low

> > DHEA, so put me on 5 mg. for about a year. I continued with it,

> then

> > switched to 7-keto, as I've read it's a safer version of DHEA.

> >

> > In the last year I've begun to feel terrible -- crippling

> depression,

> > exhaustion, etc..., had my thyroid panels done, and came up low.

> So I

> > upped my Armour by another 1/2 grain twice a day. After a few

days

> I

> > could really feel it, and began to feel much better.

> >

> > It's been about 2 1/2 weeks, and I'm suddenly being hit by

> exhuastion

> > mid-morning, which lasts until I collapse into bed at 8:00 p.m.

It

> > could just be another flu bug my darling daughter has brought

home

> > from school -- or -- could my adrenals be complaining?

> >

> > I've been taking 25 mg. of 7-keto daily. I just purchased a

bottle

> of

> > Enzymatic Therapy " Fatigued to Fantastic Adrenal Stress-End " --

> which

> > contains Vit. C, Vit. B6, Pantothenic acid, Adrenal Polypeptide

> > Fractions, Betaine, L-Tyrosine, Licorice root extract, and

Adrenal

> > Cortex Extract (bovine). Should I take this too?

> >

> > And -- I also picked up " Thyroid and L-Tyrosine Complex " by the

> same

> > company. It contains Vit. B12, potassium iodide, magnesium, zinc,

> > copper, manganese, molybdenum, L-tyrosine, multi-glandular comlex

> > (liver, lung, pancreas, heart, kidney, spleen), Thyroid Extract

> > (thyroxin-free). I haven't taken this yet, am not sure I

shouldn't

> > just take it back to the health food store -- since I'm trying to

> > find my optimum Armour dose. But do you guys have any opinions on

> > this product?

> >

> > I have an appt. to see the assistant of my impossible-to-see-

> before-6-

> > months-I-don't-take-insurance-money-up-front-bow-at-my-throne

> doctor

> > (gee, do ya think I'm a bit hostile???) in a couple weeks. I want

> to

> > make sure I'm doing the right thing.

> >

> > I had an anaphylactic allergic reaction in June, went to the

> hospital

> > and did lots of intravenous and oral steroids. My skin has been

> acne-

> > riddled ever since (which I haven't had for over 20 years). I

> guess I

> > should get my cortisol and DHEA levels checked again -- but I

> don't

> > think I'm low in cortisol.. guess I don't know.

> >

> > Any comments are greatly appreciated!!!

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> Does anyone know how massive amounts of intravenous and oral

steroids

> can affect the thyroid?

the only thing i am thinking is that it shut down your adrenals and

they are still trying to get back to producing the amount of hormones

they need to, and so therefore are very stressed Thyroid and adrenal

function are very closely connected.

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Massive doses of steroids, slow down thyroid function. Too little

slows it and too much slows it. They cause decrease thyroid

stimulation hormone (TSH), decreased production of the thyroid

gland, and decreased thyroid binding globulin, the protein that

transports thryoid in the blood. These changes should be reversed

within weeks after disontinuing steroids.

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Massive doses of steroids, slow down thyroid function. Too little

slows it and too much slows it. They cause decrease thyroid

stimulation hormone (TSH), decreased production of the thyroid

gland, and decreased thyroid binding globulin, the protein that

transports thryoid in the blood. These changes should be reversed

within weeks after disontinuing steroids.

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Massive doses of steroids, slow down thyroid function. Too little

slows it and too much slows it. They cause decrease thyroid

stimulation hormone (TSH), decreased production of the thyroid

gland, and decreased thyroid binding globulin, the protein that

transports thryoid in the blood. These changes should be reversed

within weeks after disontinuing steroids.

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Do you have a reference for that? I have had major problems with

steroids!

Thanks

> Massive doses of steroids, slow down thyroid function. Too little

> slows it and too much slows it. They cause decrease thyroid

> stimulation hormone (TSH), decreased production of the thyroid

> gland, and decreased thyroid binding globulin, the protein that

> transports thryoid in the blood. These changes should be reversed

> within weeks after disontinuing steroids.

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  • 4 weeks later...

Hi, Just ran across your comment about steroids. I also would add

that large doses of steroids create an artificial stress situation in

the body and cause a switch in the conversion of T4 to T3 and result

in more conversion the RevT3, which is physiologically inactive. The

T4-RevT3 conversion is energy conversing (as oppposed to the T3-T3

conversion reaction) and results in a preponderance on the inactive

RevT3 at the cellular level.

> Massive doses of steroids, slow down thyroid function. Too little

> slows it and too much slows it. They cause decrease thyroid

> stimulation hormone (TSH), decreased production of the thyroid

> gland, and decreased thyroid binding globulin, the protein that

> transports thryoid in the blood. These changes should be reversed

> within weeks after disontinuing steroids.

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Hi, Just ran across your comment about steroids. I also would add

that large doses of steroids create an artificial stress situation in

the body and cause a switch in the conversion of T4 to T3 and result

in more conversion the RevT3, which is physiologically inactive. The

T4-RevT3 conversion is energy conversing (as oppposed to the T3-T3

conversion reaction) and results in a preponderance on the inactive

RevT3 at the cellular level.

> Massive doses of steroids, slow down thyroid function. Too little

> slows it and too much slows it. They cause decrease thyroid

> stimulation hormone (TSH), decreased production of the thyroid

> gland, and decreased thyroid binding globulin, the protein that

> transports thryoid in the blood. These changes should be reversed

> within weeks after disontinuing steroids.

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Hi, Just ran across your comment about steroids. I also would add

that large doses of steroids create an artificial stress situation in

the body and cause a switch in the conversion of T4 to T3 and result

in more conversion the RevT3, which is physiologically inactive. The

T4-RevT3 conversion is energy conversing (as oppposed to the T3-T3

conversion reaction) and results in a preponderance on the inactive

RevT3 at the cellular level.

> Massive doses of steroids, slow down thyroid function. Too little

> slows it and too much slows it. They cause decrease thyroid

> stimulation hormone (TSH), decreased production of the thyroid

> gland, and decreased thyroid binding globulin, the protein that

> transports thryoid in the blood. These changes should be reversed

> within weeks after disontinuing steroids.

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