Guest guest Posted April 6, 2010 Report Share Posted April 6, 2010 Wont the toxocity only happen if ferritin gets very high? Or??Sendt fra min iPhoneDen 6. apr. 2010 kl. 14.05 skrev "rainbow00brite" : > Sure TIBC is low in range. This means that there is little > Transferrin (protein that binds Iron to make Ferritin) left > to safely bind Iron. Unbound Iron in the blood is TOXIC & is > what has potential to deposit in Organs (damaging them) & > also causes oxidation & free radicals. How does one go about raising their TIBC? ~Rainbow~ 30 year old Female 5'6" 136lbs Dx: Hashi's, AF, Wheat Sensitivity Rx/OTC: Cynomel 68.75mcg, HC 27.5mg, Florinef 1tab, Potassium 90mEq, Sea Salt 3/4tsp My Log and Labs: http://tinyurl.com/pvgjmb My Blog: http://hyporainbow.wordpress.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2010 Report Share Posted April 6, 2010 I do (or did) have very low progesterone. About the same time I started having the problems was when my days 14-28 came along and I was using progesterone cream. Could it be possible that the HC/T3 treatment has left me not needing as much progesterone? Interesting you mention anxiety and sex hormones. I had a total emotional breakdown yesterday! It was real bad.... I decreased the HC by 2.5mg and forgot to take the Erfa. The test was done in the morning, not fasting. I only had coffee, I take no iron supplements. And was done prior to starting the HC/T3 treatment. Maybe I should test again. > > > > > > I've been on HC/T3 for almost 4 months. I can't seem to be able to increase the T3. Symptoms,pressure in chest,shortness of breath, throat tightness, anxiety and just grumpy. (I did have increased stress during this time also) My dosage is very low. Dr seems to think my adrenals are stabilized and the extra thyroid is causing anxiety. He's instructed me to start weaning off the HC, then to try increasing the T3. > > > > > > I would like some opinions on this. I was Stage 5 adrenal fatique. > > > > > > Last months Labs are: > > > Free T4 -.73 (.82-1.77) > > > TSH - 3.170 (.450-4.500) > > > Reverse T3 - 120pg (90-350) > > > Free T3 - 3.2pg (2.0-4.4) > > > > > > Test prior to starting HC/T3: > > > Free T4 - 1.67 (.8-1.18) > > > TSH - .01 (.40-4.50) > > > Reverse T3 - 47ng (11-32) > > > Free T3 - 374 (230-420) > > > > > > Temps are stable at 98.4 > > > Pulse is 80. > > > > > > Current Dosage HC 22.5, Erfa 60mg, T3 25mcg > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2010 Report Share Posted April 6, 2010 Hi >>>Wont the toxocity only happen if ferritin gets very high?<<<< No Iron Toxicity is related to ability of body to SAFELY store it as Ferritin. That is related to Transferrin levels (which binds Iron to form Ferritin), stomach acidity, Iron ingestion, Liver health, and rate iron is absorbed (HH folks absorb a lot, Celiacs may absorb little, PA folks often have trouble with BOTH B12 & Iron). If Transferrin is low for whatever reason then ability to bind iron is reduced too. eg. genetic mutations, antibodies, Liver disease, etc. Transferrin may be INCREASED by body to increase Ferritin stores when you have infection as body is protecting you (removing free iron from blood). Transferrin may be DECREASED if you are Iron Anemic so body can take it from blood & use in Red Cell production. In Hemochromatosis it's true that Ferritin may get very high. That's dangerous NOT because of the Ferritin itself but because it shows high Iron loading & likely FREE Iron depositing in organs, brain, muscles, joints etc. That's why Iron loading is dxed using saturation & transferrin levels as well as Ferritin levels. It's Iron deposits that are dangerous NOT Ferritin. Lethal Lee Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2010 Report Share Posted April 7, 2010 Is transferrin an important blood test to have run? I've never had it before so was just curious if it tells a story that the typical iron panel tests would not necessarily tell. Also, not sure if you saw my previous question, but I was wondering how a person gets their TIBC up? Mine used to be fine, but was abysmal on my latest panel..along with low iron, iron sat and UIBC: 01.12.09 Iron TIBC - 355 (range 228 - 438) 07.09.09 Iron TIBC - 264 (range 250 - 450) 09.16.09 Iron TIBC - 331 (range 250 - 450) 02.22.10 Iron TIBC - 175 L (range 250 - 450) ~Rainbow~ 30 year old Female 5'6 " 136lbs Dx: Hashi's, AF, Wheat Sensitivity Rx/OTC: Cynomel 68.75mcg, HC 27.5mg, Florinef 1tab, Potassium 90mEq, Sea Salt 3/4tsp My Log and Labs: http://tinyurl.com/pvgjmb My Blog: http://hyporainbow.wordpress.com > > Hi > > >>>Wont the toxocity only happen if ferritin gets very high?<<<< > > No Iron Toxicity is related to ability of body to SAFELY store it as Ferritin. > > That is related to Transferrin levels (which binds Iron to form Ferritin), stomach acidity, Iron ingestion, Liver health, and rate iron is absorbed (HH folks absorb a lot, Celiacs may absorb little, PA folks often have trouble with BOTH B12 & Iron). > > If Transferrin is low for whatever reason then ability to bind iron is reduced too. eg. genetic mutations, antibodies, Liver disease, etc. > Transferrin may be INCREASED by body to increase Ferritin stores when you have infection as body is protecting you (removing free iron from blood). Transferrin may be DECREASED if you are Iron Anemic so body can take it from blood & use in Red Cell production. > > In Hemochromatosis it's true that Ferritin may get very high. > That's dangerous NOT because of the Ferritin itself but because it shows high Iron loading & likely FREE Iron depositing in organs, brain, muscles, joints etc. That's why Iron loading is dxed using saturation & transferrin levels as well as Ferritin levels. > > It's Iron deposits that are dangerous NOT Ferritin. > > Lethal Lee > Quote Link to comment Share on other sites More sharing options...
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