Global Vaccination Programs: Challenges Ahead

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ALSO IN THIS ISSUE:NEWSMEMBER NEWSUSER SUPPORT

NEW FEATURES THIS WEEK

Conference Report - Global Vaccines -- What Are the Challenges?

In 2001, 1.5 million deaths occurred among children below 5 years of age that could have been prevented by vaccination. How can we immunize every child, everywhere?Medscape General Medicine 5(4) 2003

Conference Report - II. Investigating New Vaccines: SARS

Sophisticated coronavirus vectors are being refined for use as SARS vaccines.Medscape General Medicine 5(4) 2003

Detection of Mature T-Cell Leukemias by Flow Cytometry Using Anti-T-Cell Receptor VB Antibodies

Evaluation for T-cell monoclonality often is necessary for the diagnosis of T-cell malignancy.Am J Clin Pathol 120(5) 2003

Decreased Response to IL-12 and IL-18 of Peripheral Blood Cells in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic disorder of unknown aetiology primarily affecting joints and leading to their progressive destruction.Arthritis Res Ther 6(1) 2003

FOCUS ON ACID-RELATED DISORDERS

The use of PPIs has dramatically altered management of acid-peptic disorders. Cash, MD, discusses latest findings on clinical applications and outcomes associated with use of both IV and oral

PPIs, in "Proton-Pump Inhibitors: Clinical Applications," a featured

conference report in the Gastroesophageal Reflux Disease Resource

Center.

NEWS

U.N. Puts off Cloning Ban Treaty Talks for a Year

The U.N. General Assembly on Monday decided to put off for a year negotiations for a controversial global treaty banning human cloning that the Bush administration wants to extend to research on stem cells.Reuters Health Information 2003

Red Blood Cells Implicated in Disruption of Coronary Plaques

New research suggests that by contributing free cholesterol, erythrocytes play an important role in the progression of coronary atherosclerotic plaques. This finding helps establish a link between intraplaque hemorrhage and plaque progression.Reuters Health Information 2003

Islet Transplantation May Be Justified for Only Most Severe Type 1 Diabetes

A research team at the US National Institutes of Health suggests that pancreatic islet transplantation may be appropriate only for those patients with severe "end-stage" type 1 diabetes resistant to an optimal treatment regimen.Reuters Health Information 2003

Germ Stem Cell-Derived Sperm Cells Capable of Fertilizing Oocytes

Fertile, male haploid germ cells now join the ranks of cell types that can be generated from embryonic stem cells, scientists in Massachusetts report in the early edition of Nature, available online December 10. Reuters Health Information 2003

Iceland's DeCODE Finds Two More Obesity Genes

Icelandic biotech company deCODE genetics Inc said on Thursday it had isolated two more genes that can predispose people to obesity, offering new targets for drug intervention in the future.Reuters Health Information 2003

EGFR Expression in Breast Cancer Linked to Aggressive Disease

Researchers said on Friday they have found epidermal growth factor receptor, or EGFR, expression in breast tumors is associated with poorer prognosis.Reuters Health Information 2003

BP1 Linked to Aggressive Breast Cancer

Gene is found in 89% of African-American women.Medscape Medical News 2003

Vaccination With Virus-Like Particles Protects Mice From Ebola

Vaccination with Ebola virus-like particles (eVLPs) can completely protect mice from a subsequent challenge with the virus, according to a report published in the December 8th early edition of the Proceedings of the National Academy of Sciences.Reuters Health Information 2003

First Validated Breast Cancer Gene Assay

Score accurately predicts 10-year risk for node-negative, ER-positive women treated with tamoxifen.Medscape Medical News 2003

Animal Studies Indicate That Cocaine and Ecstasy Cause DNA Mutations

Cocaine and Ecstasy not only cause addiction and raise the risk of cancer but also provoke genetic mutations, Italian scientists said on Friday.Reuters Health Information 2003

M. tuberculosis Proteasome Needed for Nitric Oxide Resistance

The proteasome found in Mycobacterium tuberculosis plays a key role in protecting the organism against nitric oxide and other reactive nitrogen intermediates (RNI) produced by the host, new research indicates.Reuters Health Information 2003

Anti-IL-5 Therapy Shows Promise as Treatment for Eosinophilic Dermatitis

Findings from three case reports suggest that mepolizumab, an anti-interleukin-5 (IL-5) antibody, is a safe and effective treatment for eosinophilic dermatitis in patients with elevated IL-5 levels. Reuters Health Information 2003

New Animal Model Could Unlock Secrets of Early Pancreatic Cancer

US researchers have created a murine model of invasive pancreatic ductal cancer that more closely mimics the human disease than previous models. Reuters Health Information 2003

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