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AP & DMARDs

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I have a question about combining other DMARDs with the AP. I have

psoriatic arthritis and have been taking Minocin (100mg daily) for a

2 and a half months. About a month ago I had to start taking

prednisone too because of a very bad flare (maybe a herx reaction?).

I took 20 mg of prednisone for 5 days, then 15 mg for three days, etc

until I tapered down to my current dose: for the last 30 days I have

been averaging between 2 and 3.75 mg, 3 days on 2 or 3 days off,

keeping the flare at a somewhat manageable level. The prednisone is

really effective! But I'm now starting to get concerned about

staying on it for a longer time (worried about long term side effects

such as osteoporosis, diabetes, " moonface " , weight gain) and am

thinking about trying MTX instead. Does anyone have any views about

which concurrent treatment would be better/safer: Minocin and

prednisone or Minocin and MTX? Is prednisone at my low/intermittent

dose likely to cause side effects? (I think I've already gained a

few pounds as a result).

Thanks,

Sharon

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