Re: clindamycin IV & herx reaction

September 15, 2003

In a message dated 9/14/2003 9:15:24 PM Pacific Daylight Time,

pooprstein@... writes:

Has any one had this kind of

reaction and found out that it was the dosage not a herx? Sorry for

the long post!

Sometimes you can be allergic to some antibiotics. I can' t take Miocins.

like Erithomician, etc, and my mama is allergic to pennicillin. But, I can take

the Doxy and I do. Ya know them bugs that are making you sick freak out when

you try and kill em so just think of it as a battle for your body. You are not a

bug buffet. Kick the buggers out and sometimes you got to just hunker down

and let the doctors do their work, if you are not allergic to the antibiotic,

you may feel worse, but sooner or later you will feel better and will get your

life back.

Pritchard

" Those who were seen dancing

were thought to be insane

by those who could not hear the music "

quote by Nietze

September 15, 2003

Thanks for the info and taking the time to respond but I have read all that

and am not sure what you are trying to point out? If you mean the dosage was

too high, I think I agree but my problem is that I am seeing a dr who is

supposed to be really good and actually studied with Dr. Brown so he wants to do

it

Browns way. I guess I'm not really sure what I'm looking for in a response, I

suppose just someone who has had the same experince with the IV and whether

or not they tried it again and what happened.

In a message dated 9/15/2003 8:46:18 AM Eastern Daylight Time,

ellenmccool@... writes:

> Dear Pooprstein,

>

> THIS IS FROM THE FAQ AT <A

HREF= " http://www.rheumatic.org/ " >http://www.rheumatic.org/</A>

>

> " Typically, patients with severe and/or long-standing disease are started

> with a series of daily intravenous clindamycin for five to seven days. (Some

> doctors are using lincocin with equal success.) The first two days, 300 mg. of

> clindamycin would be administered in 250 cc 0.9% saline dripped over a 50 to

> 60 minute period. (D5W is not used because of the yeast overgrowth found in

> most of these patients.) The third and fourth day 600 mg. is given, and the

> fifth and any subsequent days 900 mg. (A. Franco, M.D., a

rheumatologist

> in Riverside, California often prescribes a seven- day series every five

> weeks four times and then reassesses the patient's need. In some of his

patients

> with rheumatoid arthritis, Dr. Franco is substituting Zithromax 250 mg.

> twice daily two days a week in place of the IV clindamycin.) After the initial

> daily series, IVs may be administered weekly, every other week or as the

> physician determines for the individual patient. The IVs are continued until

all

> lab figures return to normal. Lab figures should then be monitored for a time

> to be sure patient remains stable before discontinuing the IVs. For sensitive

> patients, a local anesthetic may be applied to the injection site. "

>

> Ellen McCool

>

> From: <A HREF= " mailto:pooprstein@... " >pooprstein</A>

>

> >> <A

HREF= " mailto:rheumatic " >rheumatic </A>

>> Sent: Monday, September 15, 2003 12:20 AM

>> Subject: rheumatic clindamycin IV & herx reaction

>>

>> I have a question about herxing, hopefully someone has had the same

>> experience...After tons of reading and research I decided to go ahead

>> with the antibiotic therapy. I have a dr. in my area that studied

>> with dr. brown and gives the treatment starting out with IV for 5

>> days. Well, I lasted one day! The IV was 800mg of clindicin (sp?)

>> and as soon as she stuck the needed in my arm I started to have a

>> reaction. On my way home from the office I started to feel so sick

>> that I wanted to jump out of my skin. I read about the herx reaction

>> and did expect to have some side effects but didn't expect what I

>> got...over the next two days my fever went up and down to about 103

>> and I was so weak that I could barely get up to go to the bathroom, I

>> was shaking and could not lay still, & my head was pounding, the

>> weird thing is that I was not having more severe symptoms of my

>> disease, no flares at all I just felt like someone had run me over

>> with a truck. I have palindromic rheumatism and was just diagnosed

>> about 6 months ago and part of me expected to just feel a little

>> nausea because it is so early in my disease. I truely feel like it

>> was some type of overdose reaction to the meds and not a herx. I am

>> so sensitive to any kind of medicine even over the counter cold. the

>> dr thinks I'm crazy and I don't think he believed how unable to

>> function I was. I don't know what to do???He wants me to try it

>> again and I don't know if I can. Has any one had this kind of

>> reaction and found out that it was the dosage not a herx? Sorry for

>> the long post!

>>

>> To unsubscribe, email: <A

HREF= " mailto:rheumatic-unsubscribeegroups " >rheumatic-unsubscribe@...\

m</A>

>>

September 15, 2003

hi.....i get the clindamycin IV's every 4 weeks for 5 days at 900 mg. when i

began getting them i infused them much too quickly and got a headache and

reeeeeeeeally tired. i guess i could say flu like. now that i get them slower

i

do not get the headache but i still feel tired. i hope this helps. ask me

any questions....i have gotten the course of 5 days times now.

rachael

September 15, 2003

Dear Pooprstein,

THIS IS FROM THE FAQ AT http://www.rheumatic.org/

" Typically, patients with severe and/or long-standing disease are started with a

series of daily intravenous clindamycin for five to seven days. (Some doctors

are using lincocin with equal success.) The first two days, 300 mg. of

clindamycin would be administered in 250 cc 0.9% saline dripped over a 50 to 60

minute period. (D5W is not used because of the yeast overgrowth found in most of

these patients.) The third and fourth day 600 mg. is given, and the fifth and

any subsequent days 900 mg. (A. Franco, M.D., a rheumatologist in

Riverside, California often prescribes a seven- day series every five weeks four

times and then reassesses the patient's need. In some of his patients with

rheumatoid arthritis, Dr. Franco is substituting Zithromax 250 mg. twice daily

two days a week in place of the IV clindamycin.) After the initial daily series,

IVs may be administered weekly, every other week or as the physician determines

for the individual patient. The IVs are continued until all lab figures return

to normal. Lab figures should then be monitored for a time to be sure patient

remains stable before discontinuing the IVs. For sensitive patients, a local

anesthetic may be applied to the injection site. "

Ellen McCool

From: pooprstein

rheumatic

Sent: Monday, September 15, 2003 12:20 AM

Subject: rheumatic clindamycin IV & herx reaction

I have a question about herxing, hopefully someone has had the same

experience...After tons of reading and research I decided to go ahead

with the antibiotic therapy. I have a dr. in my area that studied

with dr. brown and gives the treatment starting out with IV for 5

days. Well, I lasted one day! The IV was 800mg of clindicin (sp?)

and as soon as she stuck the needed in my arm I started to have a

reaction. On my way home from the office I started to feel so sick

that I wanted to jump out of my skin. I read about the herx reaction

and did expect to have some side effects but didn't expect what I

got...over the next two days my fever went up and down to about 103

and I was so weak that I could barely get up to go to the bathroom, I

was shaking and could not lay still, & my head was pounding, the

weird thing is that I was not having more severe symptoms of my

disease, no flares at all I just felt like someone had run me over

with a truck. I have palindromic rheumatism and was just diagnosed

about 6 months ago and part of me expected to just feel a little

nausea because it is so early in my disease. I truely feel like it

was some type of overdose reaction to the meds and not a herx. I am

so sensitive to any kind of medicine even over the counter cold. the

dr thinks I'm crazy and I don't think he believed how unable to

function I was. I don't know what to do???He wants me to try it

again and I don't know if I can. Has any one had this kind of

reaction and found out that it was the dosage not a herx? Sorry for

the long post!

To unsubscribe, email: rheumatic-unsubscribeegroups

September 15, 2003

Hi again. Well, my daughter (systemic SD since 8/2000) has undergone the I.V.'s

several times, but initially they were given at the lower dose and were worked

up to the 900 mg dose. Now, when she has them occasionally, they are at the

higher dose - 900 mg usually. The only side effect she has experienced is the

metallic taste in her mouth. Someone else here needs to advise you about what

may be the reason you are experiencing these problems.

Ellen

rheumatic clindamycin IV & herx reaction